SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jr9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1N49_D_RITD401_2
(PROTEASE)		 5jr9 NEQ131
(Nanoarchaeum
equitans) 		4 / 6 ASP B 167
GLY B 116
ILE B 115
ILE B 172
 None
 0.91A 1n49D-5jr9B:
undetectable		 1n49D-5jr9B:
16.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 5jr9 NEQ131
(Nanoarchaeum
equitans) 		4 / 8 PHE B  77
LEU B 162
GLY B 116
VAL B  84
 None
 0.92A 2a1oA-5jr9B:
undetectable		 2a1oA-5jr9B:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FCN_B_DVAB35_0
(UBIQUITIN)		 5jr9 NEQ131
(Nanoarchaeum
equitans) 		4 / 6 LEU B  58
GLN B  62
GLU B  64
ILE B  63
 None
 0.97A 2fcnA-5jr9B:
undetectable
2fcnB-5jr9B:
undetectable		 2fcnA-5jr9B:
16.59
2fcnB-5jr9B:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1500_1
(CYTOCHROME P450 3A4)		 5jr9 NEQ131
(Nanoarchaeum
equitans) 		5 / 11 LEU B 148
ILE B 172
MET B  40
GLU B 129
LEU B  89
 None
 1.35A 2v0mA-5jr9B:
undetectable		 2v0mA-5jr9B:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_D_KLND1498_1
(CYTOCHROME P450 3A4)		 5jr9 NEQ131
(Nanoarchaeum
equitans) 		5 / 11 LEU B 148
ILE B 172
MET B  40
GLU B 129
LEU B  89
 None
 1.35A 2v0mD-5jr9B:
undetectable		 2v0mD-5jr9B:
19.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5jr9 NEQ131
(Nanoarchaeum
equitans) 		5 / 12 ALA B  59
GLN B  62
LEU B  80
ILE B  37
LEU B  87
 None
 0.87A 3uvvB-5jr9B:
undetectable		 3uvvB-5jr9B:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_A_MXMA606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5jr9 NEQ131
(Nanoarchaeum
equitans) 		5 / 12 MET B  29
LEU B  55
VAL B 106
LEU B  80
LEU B  87
 None
 1.44A 4m11A-5jr9B:
undetectable		 4m11A-5jr9B:
16.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_A_TLFA601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5jr9 NEQ131
(Nanoarchaeum
equitans) 		3 / 3 LEU B 145
TYR B  92
SER B 126
 None
 0.77A 5iktA-5jr9B:
undetectable		 5iktA-5jr9B:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A60_D_9CRD501_0
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5jr9 NEQ131
(Nanoarchaeum
equitans) 		5 / 12 ALA B  59
GLN B  62
LEU B  80
ILE B  37
LEU B  87
 None
 1.01A 6a60D-5jr9B:
undetectable		 6a60D-5jr9B:
17.59