SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jrm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD508_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5jrm ENDO-1,4-BETA-XYLANA
SE
(Fusarium
oxysporum) 		4 / 6 PHE A  35
ASN A  29
ILE A 172
GLY A  50
 None
 1.11A 1oniD-5jrmA:
undetectable
1oniF-5jrmA:
undetectable		 1oniD-5jrmA:
21.54
1oniF-5jrmA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_F_RBFF204_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 5jrm ENDO-1,4-BETA-XYLANA
SE
(Fusarium
oxysporum) 		4 / 8 TYR A 114
ARG A 140
GLU A  90
VAL A 107
 None
None
None
SO4  A 203 (-4.1A)
 1.16A 2fl5E-5jrmA:
undetectable
2fl5F-5jrmA:
undetectable		 2fl5E-5jrmA:
21.72
2fl5F-5jrmA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_B_SALB1305_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5jrm ENDO-1,4-BETA-XYLANA
SE
(Fusarium
oxysporum) 		4 / 5 SER A  56
ARG A  57
PRO A  53
GLY A  54
 None
 1.48A 2y7kB-5jrmA:
undetectable		 2y7kB-5jrmA:
21.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4T_A_BEZA507_0
(BETA-LACTAMASE VIM-2)		 5jrm ENDO-1,4-BETA-XYLANA
SE
(Fusarium
oxysporum) 		3 / 3 THR A  21
HIS A  45
ASN A  44
 SO4  A 202 (-4.3A)
None
None
 0.92A 5n4tA-5jrmA:
undetectable		 5n4tA-5jrmA:
19.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_A_7V7A201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5jrm ENDO-1,4-BETA-XYLANA
SE
(Fusarium
oxysporum) 		4 / 8 TYR A 117
ARG A 121
GLN A 135
TRP A 137
 None
 0.71A 5tzoA-5jrmA:
27.6		 5tzoA-5jrmA:
47.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5jrm ENDO-1,4-BETA-XYLANA
SE
(Fusarium
oxysporum) 		5 / 12 TRP A  78
TYR A  87
PRO A 125
TRP A 137
TYR A 170
 GOL  A 201 ( 3.7A)
None
GOL  A 201 (-4.1A)
None
None
 0.51A 5tzoA-5jrmA:
27.6		 5tzoA-5jrmA:
47.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5jrm ENDO-1,4-BETA-XYLANA
SE
(Fusarium
oxysporum) 		5 / 12 VAL A  46
TRP A  78
TYR A  87
PRO A 125
TRP A 137
 GOL  A 201 ( 4.7A)
GOL  A 201 ( 3.7A)
None
GOL  A 201 (-4.1A)
None
 0.78A 5tzoA-5jrmA:
27.6		 5tzoA-5jrmA:
47.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5jrm ENDO-1,4-BETA-XYLANA
SE
(Fusarium
oxysporum) 		5 / 12 TRP A  78
TYR A  87
TRP A 137
TYR A 170
GLY A 177
 GOL  A 201 ( 3.7A)
None
None
None
None
 0.80A 5tzoB-5jrmA:
27.6		 5tzoB-5jrmA:
47.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_B_7V7B201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5jrm ENDO-1,4-BETA-XYLANA
SE
(Fusarium
oxysporum) 		5 / 12 VAL A  46
TRP A  78
TYR A  87
TRP A 137
GLY A 177
 GOL  A 201 ( 4.7A)
GOL  A 201 ( 3.7A)
None
None
None
 0.96A 5tzoB-5jrmA:
27.6		 5tzoB-5jrmA:
47.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_B_7V7B201_2
(ENDO-1,4-BETA-XYLANA
SE A)		 5jrm ENDO-1,4-BETA-XYLANA
SE
(Fusarium
oxysporum) 		3 / 3 ARG A 121
PRO A 125
TYR A 178
 None
GOL  A 201 (-4.1A)
None
 0.77A 5tzoB-5jrmA:
27.6		 5tzoB-5jrmA:
47.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_B_7V7B202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5jrm ENDO-1,4-BETA-XYLANA
SE
(Fusarium
oxysporum) 		4 / 8 TYR A 117
ARG A 121
GLN A 135
TRP A 137
 None
 0.59A 5tzoB-5jrmA:
27.6		 5tzoB-5jrmA:
47.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5jrm ENDO-1,4-BETA-XYLANA
SE
(Fusarium
oxysporum) 		5 / 12 TRP A  78
TYR A  87
PRO A 125
TRP A 137
TYR A 170
 GOL  A 201 ( 3.7A)
None
GOL  A 201 (-4.1A)
None
None
 0.51A 5tzoC-5jrmA:
27.5		 5tzoC-5jrmA:
47.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5jrm ENDO-1,4-BETA-XYLANA
SE
(Fusarium
oxysporum) 		5 / 12 VAL A  46
TRP A  78
TYR A  87
PRO A 125
TRP A 137
 GOL  A 201 ( 4.7A)
GOL  A 201 ( 3.7A)
None
GOL  A 201 (-4.1A)
None
 0.80A 5tzoC-5jrmA:
27.5		 5tzoC-5jrmA:
47.50
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5TZO_C_7V7C202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 5jrm ENDO-1,4-BETA-XYLANA
SE
(Fusarium
oxysporum) 		4 / 8 TYR A 117
ARG A 121
GLN A 135
TRP A 137
 None
 0.67A 5tzoC-5jrmA:
27.5		 5tzoC-5jrmA:
47.50