SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jsi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JTX_A_CVIA200_0
(HYPOTHETICAL
TRANSCRIPTIONAL
REGULATOR IN QACA
5'REGION)		 5jsi BACTERIORHODOPSIN
(Candidatus
Actinomarina
minuta) 		5 / 12 THR A 193
TYR A 192
ILE A 109
TYR A 113
TYR A  64
 None
None
LYR  A 200 ( 4.8A)
OLC  A 322 ( 3.7A)
None
 1.20A 1jtxA-5jsiA:
2.0		 1jtxA-5jsiA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_A_BEZA349_0
(D-AMINO ACID OXIDASE)		 5jsi BACTERIORHODOPSIN
(Candidatus
Actinomarina
minuta) 		4 / 5 TYR A  70
ILE A 109
ARG A 188
GLY A 175
 None
LYR  A 200 ( 4.8A)
IOD  A 316 (-3.6A)
None
 1.33A 1kifA-5jsiA:
undetectable		 1kifA-5jsiA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_B_BEZB349_0
(D-AMINO ACID OXIDASE)		 5jsi BACTERIORHODOPSIN
(Candidatus
Actinomarina
minuta) 		4 / 5 TYR A  70
ILE A 109
ARG A 188
GLY A 175
 None
LYR  A 200 ( 4.8A)
IOD  A 316 (-3.6A)
None
 1.33A 1kifB-5jsiA:
undetectable		 1kifB-5jsiA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_C_BEZC349_0
(D-AMINO ACID OXIDASE)		 5jsi BACTERIORHODOPSIN
(Candidatus
Actinomarina
minuta) 		4 / 5 TYR A  70
ILE A 109
ARG A 188
GLY A 175
 None
LYR  A 200 ( 4.8A)
IOD  A 316 (-3.6A)
None
 1.34A 1kifC-5jsiA:
undetectable		 1kifC-5jsiA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_D_BEZD349_0
(D-AMINO ACID OXIDASE)		 5jsi BACTERIORHODOPSIN
(Candidatus
Actinomarina
minuta) 		4 / 5 TYR A  70
ILE A 109
ARG A 188
GLY A 175
 None
LYR  A 200 ( 4.8A)
IOD  A 316 (-3.6A)
None
 1.34A 1kifD-5jsiA:
undetectable		 1kifD-5jsiA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_E_BEZE349_0
(D-AMINO ACID OXIDASE)		 5jsi BACTERIORHODOPSIN
(Candidatus
Actinomarina
minuta) 		4 / 5 TYR A  70
ILE A 109
ARG A 188
GLY A 175
 None
LYR  A 200 ( 4.8A)
IOD  A 316 (-3.6A)
None
 1.34A 1kifE-5jsiA:
undetectable		 1kifE-5jsiA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_F_BEZF349_0
(D-AMINO ACID OXIDASE)		 5jsi BACTERIORHODOPSIN
(Candidatus
Actinomarina
minuta) 		4 / 5 TYR A  70
ILE A 109
ARG A 188
GLY A 175
 None
LYR  A 200 ( 4.8A)
IOD  A 316 (-3.6A)
None
 1.33A 1kifF-5jsiA:
undetectable		 1kifF-5jsiA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_G_BEZG349_0
(D-AMINO ACID OXIDASE)		 5jsi BACTERIORHODOPSIN
(Candidatus
Actinomarina
minuta) 		4 / 5 TYR A  70
ILE A 109
ARG A 188
GLY A 175
 None
LYR  A 200 ( 4.8A)
IOD  A 316 (-3.6A)
None
 1.33A 1kifG-5jsiA:
undetectable		 1kifG-5jsiA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIF_H_BEZH349_0
(D-AMINO ACID OXIDASE)		 5jsi BACTERIORHODOPSIN
(Candidatus
Actinomarina
minuta) 		4 / 5 TYR A  70
ILE A 109
ARG A 188
GLY A 175
 None
LYR  A 200 ( 4.8A)
IOD  A 316 (-3.6A)
None
 1.33A 1kifH-5jsiA:
undetectable		 1kifH-5jsiA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T6Z_A_RBFA296_1
(RIBOFLAVIN
KINASE/FMN
ADENYLYLTRANSFERASE)		 5jsi BACTERIORHODOPSIN
(Candidatus
Actinomarina
minuta) 		5 / 11 THR A  88
VAL A  98
VAL A  82
GLU A 146
GLU A  96
 None
 1.33A 1t6zA-5jsiA:
undetectable		 1t6zA-5jsiA:
22.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VE9_A_BEZA352_0
(D-AMINO ACID OXIDASE)		 5jsi BACTERIORHODOPSIN
(Candidatus
Actinomarina
minuta) 		4 / 5 TYR A  70
ILE A 109
ARG A 188
GLY A 175
 None
LYR  A 200 ( 4.8A)
IOD  A 316 (-3.6A)
None
 1.27A 1ve9A-5jsiA:
undetectable		 1ve9A-5jsiA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 5jsi BACTERIORHODOPSIN
(Candidatus
Actinomarina
minuta) 		4 / 5 TYR A  70
ILE A 109
ARG A 188
GLY A 175
 None
LYR  A 200 ( 4.8A)
IOD  A 316 (-3.6A)
None
 1.21A 2du8G-5jsiA:
undetectable		 2du8G-5jsiA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_G_BEZG2352_0
(D-AMINO-ACID OXIDASE)		 5jsi BACTERIORHODOPSIN
(Candidatus
Actinomarina
minuta) 		4 / 5 TYR A 192
ILE A 109
ARG A 188
GLY A 175
 None
LYR  A 200 ( 4.8A)
IOD  A 316 (-3.6A)
None
 1.31A 2du8G-5jsiA:
undetectable		 2du8G-5jsiA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DU8_J_BEZJ3352_0
(D-AMINO-ACID OXIDASE)		 5jsi BACTERIORHODOPSIN
(Candidatus
Actinomarina
minuta) 		4 / 5 TYR A  70
ILE A 109
ARG A 188
GLY A 175
 None
LYR  A 200 ( 4.8A)
IOD  A 316 (-3.6A)
None
 1.22A 2du8J-5jsiA:
undetectable		 2du8J-5jsiA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OAX_E_SNLE5001_2
(MINERALOCORTICOID
RECEPTOR)		 5jsi BACTERIORHODOPSIN
(Candidatus
Actinomarina
minuta) 		4 / 4 LEU A  79
TRP A 169
LEU A 203
MET A  16
 LFA  A 306 ( 4.9A)
LYR  A 200 ( 3.6A)
None
LYR  A 200 ( 4.0A)
 0.99A 2oaxE-5jsiA:
1.0		 2oaxE-5jsiA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1358_1
(PROSTAGLANDIN
REDUCTASE 2)		 5jsi BACTERIORHODOPSIN
(Candidatus
Actinomarina
minuta) 		4 / 6 ASP A  72
TYR A 192
PHE A   9
TYR A  52
 LYR  A 200 ( 4.3A)
None
None
None
 1.21A 2w98A-5jsiA:
undetectable
2w98B-5jsiA:
undetectable		 2w98A-5jsiA:
22.95
2w98B-5jsiA:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E9X_A_NIMA1_1
(LACTOTRANSFERRIN')		 5jsi BACTERIORHODOPSIN
(Candidatus
Actinomarina
minuta) 		4 / 4 GLU A 124
GLY A 115
THR A 117
GLU A 116
 None
None
None
IOD  A 316 (-2.4A)
 0.99A 3e9xA-5jsiA:
undetectable		 3e9xA-5jsiA:
20.18