SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jsz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EE2_B_CHDB1250_0
(ALCOHOL
DEHYDROGENASE)		 5jsz CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN
(Lactobacillus
delbrueckii) 		3 / 3 MET C 139
LEU C 142
SER C 143
 None
 0.49A 1ee2A-5jszC:
undetectable		 1ee2A-5jszC:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_1
(HIV-1 PROTEASE)		 5jsz CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN
(Lactobacillus
delbrueckii) 		5 / 12 GLY C  64
ALA C  65
ASP C  68
ILE C  83
GLY C  84
 None
 0.89A 1hxbA-5jszC:
undetectable		 1hxbA-5jszC:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HM1_B_J3ZB1_1
(ESTROGEN RECEPTOR)		 5jsz CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN
(Lactobacillus
delbrueckii) 		5 / 11 LEU C  19
LEU C  16
GLU C  12
GLY C  52
LEU C  54
 None
 1.20A 3hm1B-5jszC:
undetectable		 3hm1B-5jszC:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UIL_H_QI9H1223_0
(FAB 314.1)		 5jsz CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN
(Lactobacillus
delbrueckii) 		5 / 12 ALA C  65
SER C  67
GLY C  97
LEU C  51
PRO C  93
 None
 1.30A 4uilH-5jszC:
undetectable
4uilL-5jszC:
undetectable		 4uilH-5jszC:
20.94
4uilL-5jszC:
18.87