SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jt4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWH_A_PEMA501_1
(HEMOGLOBIN ALPHA
CHAIN)		 5jt4 CYTOCHROME C'
(Achromobacter
xylosoxidans) 		4 / 6 ALA A 114
LYS A 117
ASP A 121
ALA A 122
 None
 0.41A 1iwhA-5jt4A:
undetectable		 1iwhA-5jt4A:
23.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT6_B_DESB128_1
(TRANSTHYRETIN)		 5jt4 CYTOCHROME C'
(Achromobacter
xylosoxidans) 		4 / 5 LEU A  18
ALA A  16
LEU A  51
SER A  52
 None
HEC  A 201 (-3.4A)
None
None
 1.14A 1tt6B-5jt4A:
undetectable		 1tt6B-5jt4A:
23.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YLD_A_ASCA130_0
(CYTOCHROME C')		 5jt4 CYTOCHROME C'
(Achromobacter
xylosoxidans) 		5 / 5 ALA A  20
GLY A 113
CYH A 116
LYS A 117
HIS A 120
 ASC  A 202 ( 3.3A)
ASC  A 202 (-3.9A)
HEC  A 201 (-1.9A)
None
HEC  A 201 (-3.2A)
 0.35A 2yldA-5jt4A:
24.9		 2yldA-5jt4A:
99.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YLG_A_ASCA130_0
(CYTOCHROME C')		 5jt4 CYTOCHROME C'
(Achromobacter
xylosoxidans) 		4 / 5 ALA A  16
CYH A 116
LYS A 117
HIS A 120
 HEC  A 201 (-3.4A)
HEC  A 201 (-1.9A)
None
HEC  A 201 (-3.2A)
 1.36A 2ylgA-5jt4A:
25.1		 2ylgA-5jt4A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2YLG_A_ASCA130_0
(CYTOCHROME C')		 5jt4 CYTOCHROME C'
(Achromobacter
xylosoxidans) 		5 / 5 ALA A  20
GLY A 113
CYH A 116
LYS A 117
HIS A 120
 ASC  A 202 ( 3.3A)
ASC  A 202 (-3.9A)
HEC  A 201 (-1.9A)
None
HEC  A 201 (-3.2A)
 0.29A 2ylgA-5jt4A:
25.1		 2ylgA-5jt4A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DQT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5jt4 CYTOCHROME C'
(Achromobacter
xylosoxidans) 		4 / 7 PHE A  79
GLU A  71
SER A  74
TRP A  73
 HEC  A 201 (-4.4A)
None
None
None
 1.19A 3dqtA-5jt4A:
undetectable
3dqtB-5jt4A:
2.2		 3dqtA-5jt4A:
15.09
3dqtB-5jt4A:
15.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3ZWI_A_ASCA156_0
(CYTOCHROME C')		 5jt4 CYTOCHROME C'
(Achromobacter
xylosoxidans) 		5 / 5 ALA A  20
GLY A 113
CYH A 116
LYS A 117
HIS A 120
 ASC  A 202 ( 3.3A)
ASC  A 202 (-3.9A)
HEC  A 201 (-1.9A)
None
HEC  A 201 (-3.2A)
 0.36A 3zwiA-5jt4A:
24.9		 3zwiA-5jt4A:
99.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4CIP_A_ASCA130_0
(CYTOCHROME C')		 5jt4 CYTOCHROME C'
(Achromobacter
xylosoxidans) 		4 / 4 ALA A  20
GLY A 113
CYH A 116
HIS A 120
 ASC  A 202 ( 3.3A)
ASC  A 202 (-3.9A)
HEC  A 201 (-1.9A)
HEC  A 201 (-3.2A)
 0.10A 4cipA-5jt4A:
25.0		 4cipA-5jt4A:
99.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5J_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5jt4 CYTOCHROME C'
(Achromobacter
xylosoxidans) 		4 / 7 PHE A  79
GLU A  71
SER A  74
TRP A  73
 HEC  A 201 (-4.4A)
None
None
None
 1.26A 4k5jA-5jt4A:
undetectable
4k5jB-5jt4A:
undetectable		 4k5jA-5jt4A:
14.38
4k5jB-5jt4A:
14.38
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JLI_A_ASCA202_0
(CYTOCHROME C')		 5jt4 CYTOCHROME C'
(Achromobacter
xylosoxidans) 		4 / 5 ALA A  16
CYH A 116
LYS A 117
HIS A 120
 HEC  A 201 (-3.4A)
HEC  A 201 (-1.9A)
None
HEC  A 201 (-3.2A)
 1.36A 5jliA-5jt4A:
25.2		 5jliA-5jt4A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JLI_A_ASCA202_0
(CYTOCHROME C')		 5jt4 CYTOCHROME C'
(Achromobacter
xylosoxidans) 		5 / 5 ALA A  20
GLY A 113
CYH A 116
LYS A 117
HIS A 120
 ASC  A 202 ( 3.3A)
ASC  A 202 (-3.9A)
HEC  A 201 (-1.9A)
None
HEC  A 201 (-3.2A)
 0.17A 5jliA-5jt4A:
25.2		 5jliA-5jt4A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JRA_A_ASCA202_0
(CYTOCHROME C')		 5jt4 CYTOCHROME C'
(Achromobacter
xylosoxidans) 		4 / 4 GLY A 113
CYH A 116
LYS A 117
HIS A 120
 ASC  A 202 (-3.9A)
HEC  A 201 (-1.9A)
None
HEC  A 201 (-3.2A)
 0.12A 5jraA-5jt4A:
24.6		 5jraA-5jt4A:
99.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JSL_A_ASCA202_0
(CYTOCHROME C')		 5jt4 CYTOCHROME C'
(Achromobacter
xylosoxidans) 		4 / 4 ALA A  20
GLY A 113
CYH A 116
HIS A 120
 ASC  A 202 ( 3.3A)
ASC  A 202 (-3.9A)
HEC  A 201 (-1.9A)
HEC  A 201 (-3.2A)
 0.07A 5jslA-5jt4A:
25.0		 5jslA-5jt4A:
99.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JT4_A_ASCA202_0
(CYTOCHROME C')		 5jt4 CYTOCHROME C'
(Achromobacter
xylosoxidans) 		4 / 5 ALA A  16
CYH A 116
LYS A 117
HIS A 120
 HEC  A 201 (-3.4A)
HEC  A 201 (-1.9A)
None
HEC  A 201 (-3.2A)
 1.44A 5jt4A-5jt4A:
26.1		 5jt4A-5jt4A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JT4_A_ASCA202_0
(CYTOCHROME C')		 5jt4 CYTOCHROME C'
(Achromobacter
xylosoxidans) 		5 / 5 ALA A  20
GLY A 113
CYH A 116
LYS A 117
HIS A 120
 ASC  A 202 ( 3.3A)
ASC  A 202 (-3.9A)
HEC  A 201 (-1.9A)
None
HEC  A 201 (-3.2A)
 0.02A 5jt4A-5jt4A:
26.1		 5jt4A-5jt4A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VVN_B_H4BB502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5jt4 CYTOCHROME C'
(Achromobacter
xylosoxidans) 		4 / 7 PHE A  79
GLU A  71
SER A  74
TRP A  73
 HEC  A 201 (-4.4A)
None
None
None
 1.22A 5vvnA-5jt4A:
undetectable
5vvnB-5jt4A:
undetectable		 5vvnA-5jt4A:
14.38
5vvnB-5jt4A:
14.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV6_B_H4BB501_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5jt4 CYTOCHROME C'
(Achromobacter
xylosoxidans) 		4 / 7 SER A  74
TRP A  73
PHE A  79
GLU A  71
 None
None
HEC  A 201 (-4.4A)
None
 1.24A 6av6A-5jt4A:
undetectable
6av6B-5jt4A:
undetectable		 6av6A-5jt4A:
18.55
6av6B-5jt4A:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV7_A_H4BA502_1
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5jt4 CYTOCHROME C'
(Achromobacter
xylosoxidans) 		4 / 7 SER A  74
TRP A  73
PHE A  79
GLU A  71
 None
None
HEC  A 201 (-4.4A)
None
 1.18A 6av7A-5jt4A:
undetectable
6av7B-5jt4A:
undetectable		 6av7A-5jt4A:
18.55
6av7B-5jt4A:
18.55