SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5juh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_1
(DNA TOPOISOMERASE II)		 5juh ANTIFREEZE PROTEIN
(Marinomonas
primoryensis) 		4 / 7 THR A  78
TYR A 146
TYR A 151
LEU A 101
 None
 0.99A 1qzrA-5juhA:
undetectable		 1qzrA-5juhA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QZR_B_CDXB901_2
(DNA TOPOISOMERASE II)		 5juh ANTIFREEZE PROTEIN
(Marinomonas
primoryensis) 		4 / 7 THR A  78
TYR A 146
TYR A 151
LEU A 101
 None
 1.01A 1qzrB-5juhA:
undetectable		 1qzrB-5juhA:
18.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB501_1
(HEMOLYTIC LECTIN
CEL-III)		 5juh ANTIFREEZE PROTEIN
(Marinomonas
primoryensis) 		4 / 5 ASP A  73
SER A  48
GLY A  47
ASP A  67
 CA  A 206 (-2.6A)
None
CA  A 207 (-4.3A)
None
 1.07A 3w9tB-5juhA:
undetectable		 3w9tB-5juhA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1003_1
(HEMOLYTIC LECTIN
CEL-III)		 5juh ANTIFREEZE PROTEIN
(Marinomonas
primoryensis) 		4 / 5 ASP A  73
SER A  48
GLY A  47
ASP A  67
 CA  A 206 (-2.6A)
None
CA  A 207 (-4.3A)
None
 1.08A 3w9tC-5juhA:
undetectable		 3w9tC-5juhA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD501_1
(HEMOLYTIC LECTIN
CEL-III)		 5juh ANTIFREEZE PROTEIN
(Marinomonas
primoryensis) 		4 / 5 ASP A  73
SER A  48
GLY A  47
ASP A  67
 CA  A 206 (-2.6A)
None
CA  A 207 (-4.3A)
None
 1.07A 3w9tD-5juhA:
undetectable		 3w9tD-5juhA:
17.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XUE_A_SAMA303_0
(CATECHOL
O-METHYLTRANSFERASE)		 5juh ANTIFREEZE PROTEIN
(Marinomonas
primoryensis) 		5 / 12 ASN A 147
TYR A 146
ILE A 142
ILE A 153
SER A 141
 None
 1.44A 4xueA-5juhA:
undetectable		 4xueA-5juhA:
21.40