SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jui'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_A_NFZA1219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5jui CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		4 / 8 TYR A 318
PHE A 352
GLY A 317
THR A 313
 None
 1.01A 1ykiA-5juiA:
undetectable
1ykiB-5juiA:
undetectable		 1ykiA-5juiA:
18.42
1ykiB-5juiA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_B_NFZB2219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5jui CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		4 / 8 THR A 313
TYR A 318
PHE A 352
GLY A 317
 None
 1.03A 1ykiA-5juiA:
undetectable
1ykiB-5juiA:
undetectable		 1ykiA-5juiA:
18.42
1ykiB-5juiA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_C_NFZC3219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5jui CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		4 / 8 TYR A 318
PHE A 352
GLY A 317
THR A 313
 None
 1.05A 1ykiC-5juiA:
undetectable
1ykiD-5juiA:
undetectable		 1ykiC-5juiA:
18.42
1ykiD-5juiA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YKI_D_NFZD4219_1
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5jui CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		4 / 8 THR A 313
TYR A 318
PHE A 352
GLY A 317
 None
 0.98A 1ykiC-5juiA:
undetectable
1ykiD-5juiA:
undetectable		 1ykiC-5juiA:
18.42
1ykiD-5juiA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_C_ACTC1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 5jui CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 TYR A 228
THR A 215
THR A 247
 None
 0.82A 5aoxB-5juiA:
undetectable		 5aoxB-5juiA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_F_ACTF1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 5jui CELL WALL SURFACE
ANCHOR FAMILY
PROTEIN
(Streptococcus
pneumoniae) 		3 / 3 TYR A 228
THR A 215
THR A 247
 None
 0.82A 5aoxE-5juiA:
1.1		 5aoxE-5juiA:
18.44