SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jvh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E00_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5jvh 50S RIBOSOMAL
PROTEIN L13
(Deinococcus
radiodurans) 		5 / 12 ILE G  58
ALA G  55
ASN G  84
ALA G 130
VAL G  42
 None
None
None
G  X1149 ( 3.2A)
None
 0.99A 3e00A-5jvhG:
undetectable		 3e00A-5jvhG:
18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FWD_A_BO2A801_1
(TTC1975 PEPTIDASE)		 5jvh 50S RIBOSOMAL
PROTEIN L13
(Deinococcus
radiodurans) 		5 / 9 VAL G  82
VAL G  81
VAL G 131
ILE G 127
ALA G 152
 None
 1.25A 4fwdA-5jvhG:
2.3		 4fwdA-5jvhG:
13.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNU_A_BEZA319_0
(SHKAI2IB)		 5jvh 50S RIBOSOMAL
PROTEIN L13
(Deinococcus
radiodurans) 		4 / 5 GLN G 140
HIS G 145
ILE G  75
ILE G  62
 U  X 566 ( 4.1A)
None
None
None
 1.26A 5dnuA-5jvhG:
undetectable		 5dnuA-5jvhG:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNV_A_BEZA304_0
(SHKAI2IB)		 5jvh 50S RIBOSOMAL
PROTEIN L13
(Deinococcus
radiodurans) 		4 / 5 GLN G 140
HIS G 145
ILE G  75
ILE G  62
 U  X 566 ( 4.1A)
None
None
None
 1.27A 5dnvA-5jvhG:
undetectable		 5dnvA-5jvhG:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_H_CVIH301_0
(REGULATORY PROTEIN
TETR)		 5jvh 50S RIBOSOMAL
PROTEIN L13
(Deinococcus
radiodurans) 		5 / 12 MET G 134
ALA G 130
GLU G 124
LEU G 148
VAL G  88
 G  X1148 ( 3.5A)
G  X1149 ( 3.2A)
None
None
None
 1.35A 5vlmH-5jvhG:
undetectable		 5vlmH-5jvhG:
19.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXL_B_SAMB401_0
(2-(3-AMINO-3-CARBOXY
PROPYL)HISTIDINE
SYNTHASE)		 5jvh 50S RIBOSOMAL
PROTEIN L13
(Deinococcus
radiodurans) 		5 / 12 HIS G  66
VAL G  82
ARG G  61
VAL G  80
ASP G  78
 None
 1.28A 6bxlB-5jvhG:
undetectable		 6bxlB-5jvhG:
18.79