SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jvo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EII_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN II)		 5jvo ARGININE REPRESSOR
(Corynebacterium
pseudotuberculos
is) 		5 / 12 THR A 109
PHE A 155
ARG A 159
LEU A  94
LEU A  87
 None
 1.27A 1eiiA-5jvoA:
undetectable		 1eiiA-5jvoA:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1A_A_AB1A101_1
(MDR769 HIV-1
PROTEASE)		 5jvo ARGININE REPRESSOR
(Corynebacterium
pseudotuberculos
is) 		5 / 11 GLY A 113
ALA A 114
ASP A 136
THR A 132
VAL A 139
 None
None
None
TYR  A 201 (-4.3A)
None
 1.10A 4l1aA-5jvoA:
undetectable		 4l1aA-5jvoA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L6E_B_ACTB401_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT
N6-ADENOSINE-METHYLT
RANSFERASE SUBUNIT
METTL14)		 5jvo ARGININE REPRESSOR
(Corynebacterium
pseudotuberculos
is) 		4 / 6 LEU A  87
ARG A  88
ARG A 160
ARG A 159
 None
 1.03A 5l6eA-5jvoA:
undetectable
5l6eB-5jvoA:
undetectable		 5l6eA-5jvoA:
17.18
5l6eB-5jvoA:
15.03