SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jvv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QCA_A_FUAA221_1
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5jvv BETA-1,3-GLUCOSYLTRA
NSFERASE
(Paecilomyces
sp.
'thermophila') 		4 / 7 THR B 247
PHE B 285
PHE B  31
LEU B 271
 None
 0.92A 1qcaA-5jvvB:
undetectable		 1qcaA-5jvvB:
24.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CS8_A_BRLA503_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5jvv BETA-1,3-GLUCOSYLTRA
NSFERASE
(Paecilomyces
sp.
'thermophila') 		5 / 12 GLY B  85
ILE B 120
LEU B 198
LEU B 295
LEU B 242
 None
 1.22A 3cs8A-5jvvB:
undetectable		 3cs8A-5jvvB:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL9_A_DR7A100_1
(PROTEASE)		 5jvv BETA-1,3-GLUCOSYLTRA
NSFERASE
(Paecilomyces
sp.
'thermophila') 		4 / 8 ALA B  18
ASP B  17
ILE B 292
THR B 297
 None
 0.78A 3el9A-5jvvB:
undetectable		 3el9A-5jvvB:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HZN_D_ACTD229_0
(OXYGEN-INSENSITIVE
NAD(P)H
NITROREDUCTASE)		 5jvv BETA-1,3-GLUCOSYLTRA
NSFERASE
(Paecilomyces
sp.
'thermophila') 		4 / 4 ASP B 193
GLY B 234
LYS B 235
GLU B 236
 None
 1.28A 3hznD-5jvvB:
undetectable		 3hznD-5jvvB:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O8Z_A_BBIA402_1
(NAD-DEPENDENT
PROTEIN DEACETYLASE
SIRTUIN-3,
MITOCHONDRIAL)		 5jvv BETA-1,3-GLUCOSYLTRA
NSFERASE
(Paecilomyces
sp.
'thermophila') 		4 / 5 PHE B 227
HIS B 135
LEU B 159
PRO B 113
 None
 1.18A 4o8zA-5jvvB:
undetectable		 4o8zA-5jvvB:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BW4_A_SAMA301_0
(16S RRNA
(ADENINE(1408)-N(1))
-METHYLTRANSFERASE)		 5jvv BETA-1,3-GLUCOSYLTRA
NSFERASE
(Paecilomyces
sp.
'thermophila') 		5 / 12 GLY B  30
ASP B  26
PRO B  27
GLU B  77
TRP B 102
 None
 1.12A 5bw4A-5jvvB:
undetectable		 5bw4A-5jvvB:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_A_ACTA1231_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT
PUTATIVE XANTHINE
DEHYDROGENASE YAGT
IRON-SULFUR-BINDING
SUBUNIT)		 5jvv BETA-1,3-GLUCOSYLTRA
NSFERASE
(Paecilomyces
sp.
'thermophila') 		3 / 3 ARG B  75
THR B  28
ASP B  26
 None
 0.88A 5g5gA-5jvvB:
undetectable
5g5gB-5jvvB:
undetectable		 5g5gA-5jvvB:
22.81
5g5gB-5jvvB:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA605_1
(CHITINASE)		 5jvv BETA-1,3-GLUCOSYLTRA
NSFERASE
(Paecilomyces
sp.
'thermophila') 		3 / 3 TRP B 199
ILE B 210
SER B 209
 None
 0.96A 5gqbA-5jvvB:
undetectable		 5gqbA-5jvvB:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Q1S_A_AWYA1103_0
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 5jvv BETA-1,3-GLUCOSYLTRA
NSFERASE
(Paecilomyces
sp.
'thermophila') 		4 / 6 VAL B 186
ILE B 210
LYS B 296
TYR B 294
 None
 1.30A 5q1sA-5jvvB:
undetectable		 5q1sA-5jvvB:
24.23