SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jwy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5jwy PHOSPHATIDYLGLYCEROP
HOSPHATASE B
(Escherichia
coli) 		4 / 7 GLY A 196
ALA A  40
HIS A 163
THR A  47
 None
None
46E  A 301 ( 3.9A)
None
 0.91A 1c9sT-5jwyA:
undetectable
1c9sU-5jwyA:
undetectable		 1c9sT-5jwyA:
13.90
1c9sU-5jwyA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5jwy PHOSPHATIDYLGLYCEROP
HOSPHATASE B
(Escherichia
coli) 		4 / 7 GLY A 196
ALA A  40
HIS A 163
THR A  47
 None
None
46E  A 301 ( 3.9A)
None
 0.90A 1gtfL-5jwyA:
undetectable
1gtfM-5jwyA:
undetectable		 1gtfL-5jwyA:
13.90
1gtfM-5jwyA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S9Q_B_CHDB500_0
(ESTROGEN-RELATED
RECEPTOR GAMMA)		 5jwy PHOSPHATIDYLGLYCEROP
HOSPHATASE B
(Escherichia
coli) 		4 / 4 LEU A 217
VAL A 214
ILE A 218
TRP A 220
 None
 1.48A 1s9qB-5jwyA:
3.7		 1s9qB-5jwyA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_B_CHDB2_0
(LIVER
CARBOXYLESTERASE 1)		 5jwy PHOSPHATIDYLGLYCEROP
HOSPHATASE B
(Escherichia
coli) 		3 / 3 TRP A  52
LYS A 153
PRO A  51
 None
 1.42A 2dqyB-5jwyA:
undetectable		 2dqyB-5jwyA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1303_1
(LYSR-TYPE REGULATORY
PROTEIN)		 5jwy PHOSPHATIDYLGLYCEROP
HOSPHATASE B
(Escherichia
coli) 		4 / 7 PRO A  31
ILE A 143
PRO A 105
TRP A 109
 None
 0.91A 2y7kA-5jwyA:
undetectable		 2y7kA-5jwyA:
23.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_B_DGXB1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 5jwy PHOSPHATIDYLGLYCEROP
HOSPHATASE B
(Escherichia
coli) 		3 / 3 LEU A 237
VAL A 175
ARG A 181
 None
 0.87A 3b0wB-5jwyA:
3.7		 3b0wB-5jwyA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 5jwy PHOSPHATIDYLGLYCEROP
HOSPHATASE B
(Escherichia
coli) 		4 / 8 TRP A  29
TRP A 151
PHE A 106
ARG A 201
 None
 1.33A 3ccfA-5jwyA:
undetectable		 3ccfA-5jwyA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEM_A_ACRA1001_2
(ALPHA-GLUCOSIDASE)		 5jwy PHOSPHATIDYLGLYCEROP
HOSPHATASE B
(Escherichia
coli) 		4 / 5 ILE A 116
TRP A  29
TRP A 151
TRP A 208
 None
 1.34A 3wemA-5jwyA:
0.3		 3wemA-5jwyA:
15.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5jwy PHOSPHATIDYLGLYCEROP
HOSPHATASE B
(Escherichia
coli) 		4 / 8 THR A  47
GLY A 196
ALA A  40
HIS A 163
 None
None
None
46E  A 301 ( 3.9A)
 0.89A 5eezL-5jwyA:
undetectable
5eezV-5jwyA:
undetectable		 5eezL-5jwyA:
13.90
5eezV-5jwyA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5jwy PHOSPHATIDYLGLYCEROP
HOSPHATASE B
(Escherichia
coli) 		4 / 8 THR A  47
GLY A 196
ALA A  40
HIS A 163
 None
None
None
46E  A 301 ( 3.9A)
 0.89A 5ef1L-5jwyA:
undetectable
5ef1V-5jwyA:
undetectable		 5ef1L-5jwyA:
13.90
5ef1V-5jwyA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5jwy PHOSPHATIDYLGLYCEROP
HOSPHATASE B
(Escherichia
coli) 		4 / 8 THR A  47
GLY A 196
ALA A  40
HIS A 163
 None
None
None
46E  A 301 ( 3.9A)
 0.89A 5ef2L-5jwyA:
undetectable
5ef2V-5jwyA:
undetectable		 5ef2L-5jwyA:
13.90
5ef2V-5jwyA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_B_ADNB502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 5jwy PHOSPHATIDYLGLYCEROP
HOSPHATASE B
(Escherichia
coli) 		5 / 12 LEU A 137
THR A 155
HIS A 150
MET A 206
PHE A 106
 None
 1.50A 5v96B-5jwyA:
undetectable		 5v96B-5jwyA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_D_ADND502_1
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 5jwy PHOSPHATIDYLGLYCEROP
HOSPHATASE B
(Escherichia
coli) 		5 / 12 LEU A 137
THR A 155
HIS A 150
MET A 206
PHE A 106
 None
 1.49A 5v96D-5jwyA:
undetectable		 5v96D-5jwyA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_A_ADNA506_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 5jwy PHOSPHATIDYLGLYCEROP
HOSPHATASE B
(Escherichia
coli) 		4 / 6 TRP A 151
LEU A 204
GLU A  33
LEU A  38
 None
 1.20A 5xooA-5jwyA:
undetectable		 5xooA-5jwyA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 5jwy PHOSPHATIDYLGLYCEROP
HOSPHATASE B
(Escherichia
coli) 		4 / 5 LEU A 137
VAL A 133
GLU A 111
LEU A 110
 None
 1.07A 5xooB-5jwyA:
undetectable		 5xooB-5jwyA:
15.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HUP_B_DZPB502_0
(GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT
ALPHA-1,GAMMA-AMINOB
UTYRIC ACID RECEPTOR
SUBUNIT ALPHA-1
GAMMA-AMINOBUTYRIC
ACID RECEPTOR
SUBUNIT BETA-3)		 5jwy PHOSPHATIDYLGLYCEROP
HOSPHATASE B
(Escherichia
coli) 		5 / 11 ILE A 218
LEU A 222
THR A 227
THR A   8
LEU A  15
 None
 1.33A 6hupA-5jwyA:
2.1
6hupB-5jwyA:
undetectable		 6hupA-5jwyA:
16.28
6hupB-5jwyA:
15.44