SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jxf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		4 / 8 GLY A 635
ALA A 648
THR A 570
HIS A 638
 None
 0.70A 1c9sI-5jxfA:
undetectable
1c9sJ-5jxfA:
undetectable		 1c9sI-5jxfA:
7.11
1c9sJ-5jxfA:
7.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		4 / 7 GLY A 635
ALA A 648
THR A 570
HIS A 638
 None
 0.73A 1c9sT-5jxfA:
0.0
1c9sU-5jxfA:
undetectable		 1c9sT-5jxfA:
7.11
1c9sU-5jxfA:
7.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		4 / 7 GLY A 635
ALA A 648
THR A 570
HIS A 638
 None
 0.70A 1gtfL-5jxfA:
undetectable
1gtfM-5jxfA:
undetectable		 1gtfL-5jxfA:
7.11
1gtfM-5jxfA:
7.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		4 / 8 GLY A 635
ALA A 648
THR A 570
HIS A 638
 None
 0.72A 1gtfN-5jxfA:
undetectable
1gtfO-5jxfA:
undetectable		 1gtfN-5jxfA:
7.11
1gtfO-5jxfA:
7.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXD_A_ACRA734_1
(ALPHA AMYLASE)		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		4 / 6 ASN A 643
HIS A  62
TYR A 267
GLY A 269
 None
 0.99A 1mxdA-5jxfA:
undetectable		 1mxdA-5jxfA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA444_1
(ALPHA AMYLASE)		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		4 / 7 ASN A 643
HIS A  62
TYR A 267
GLY A 269
 None
 1.03A 1mxgA-5jxfA:
undetectable		 1mxgA-5jxfA:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		4 / 7 GLY A 269
PRO A 268
THR A  68
GLY A 642
 None
None
None
ASP  A 802 (-3.8A)
 0.81A 1usqA-5jxfA:
undetectable		 1usqA-5jxfA:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_I_TRPI81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		4 / 8 GLY A 635
ALA A 648
THR A 570
HIS A 638
 None
 0.68A 1utdI-5jxfA:
undetectable
1utdJ-5jxfA:
undetectable		 1utdI-5jxfA:
7.11
1utdJ-5jxfA:
7.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_C_SHHC2652_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		5 / 12 LEU A 611
ILE A 691
GLY A 218
ASP A 209
GLY A 205
 None
 0.91A 1zz1C-5jxfA:
undetectable		 1zz1C-5jxfA:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BNN_B_FCNB1199_1
(EPOXIDASE)		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		4 / 8 TYR A 376
LEU A 542
GLU A 143
ALA A 541
 None
 0.87A 2bnnA-5jxfA:
undetectable
2bnnB-5jxfA:
undetectable		 2bnnA-5jxfA:
14.36
2bnnB-5jxfA:
14.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1321_0
(CHLOROPEROXIDASE)		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		4 / 5 LEU A 452
ASN A 397
VAL A 301
ALA A 297
 None
 1.13A 2cizA-5jxfA:
undetectable		 2cizA-5jxfA:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_A_CLMA1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		4 / 7 GLY A 269
PRO A 268
THR A  68
GLY A 642
 None
None
None
ASP  A 802 (-3.8A)
 0.85A 2jklA-5jxfA:
undetectable		 2jklA-5jxfA:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		4 / 7 GLY A 269
PRO A 268
THR A  68
GLY A 642
 None
None
None
ASP  A 802 (-3.8A)
 0.85A 2jklC-5jxfA:
undetectable		 2jklC-5jxfA:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_D_CLMD1145_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		4 / 7 GLY A 269
PRO A 268
THR A  68
GLY A 642
 None
None
None
ASP  A 802 (-3.8A)
 0.86A 2jklD-5jxfA:
undetectable		 2jklD-5jxfA:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JKL_F_CLMF1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		4 / 7 GLY A 269
PRO A 268
THR A  68
GLY A 642
 None
None
None
ASP  A 802 (-3.8A)
 0.87A 2jklF-5jxfA:
undetectable		 2jklF-5jxfA:
12.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OA1_A_TRPA2003_0
(TRYPTOPHAN
HALOGENASE)		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		5 / 12 PRO A 276
ILE A 545
PHE A 373
TYR A 377
ASN A 540
 None
 1.45A 2oa1B-5jxfA:
undetectable		 2oa1B-5jxfA:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFL_A_5CHA693_1
(LACTOTRANSFERRIN)		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		4 / 4 THR A 570
VAL A 649
GLY A 645
THR A  80
 None
 0.89A 3cflA-5jxfA:
undetectable		 3cflA-5jxfA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_P_TRPP1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		4 / 7 GLY A 367
GLN A 363
VAL A 357
ILE A 545
 None
 0.82A 3fi0P-5jxfA:
undetectable		 3fi0P-5jxfA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LTW_A_HLZA302_1
(ARYLAMINE
N-ACETYLTRANSFERASE
NAT)		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		4 / 6 LEU A  77
GLU A 704
PRO A  74
HIS A 700
 None
 1.05A 3ltwA-5jxfA:
undetectable		 3ltwA-5jxfA:
17.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP9_B_IL2B901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		5 / 12 LEU A  79
VAL A 688
PHE A 690
LEU A 707
VAL A 251
 None
 1.27A 3sp9B-5jxfA:
undetectable		 3sp9B-5jxfA:
18.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EQ4_B_SALB601_1
(4-SUBSTITUTED
BENZOATES-GLUTAMATE
LIGASE GH3.12)		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		4 / 8 ARG A 215
VAL A 683
THR A 217
GLY A 202
 None
 0.73A 4eq4B-5jxfA:
undetectable		 4eq4B-5jxfA:
24.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QCK_A_ASDA404_1
(3-KETOSTEROID-9-ALPH
A-MONOOXYGENASE
OXYGENASE SUBUNIT)		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		5 / 12 LEU A 100
ALA A 321
ASN A 210
GLY A 202
ASP A 219
 None
ARG  A 801 (-3.7A)
ARG  A 801 (-2.9A)
None
None
 1.31A 4qckA-5jxfA:
undetectable		 4qckA-5jxfA:
19.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V04_B_0LIB1771_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		5 / 12 ALA A 279
GLU A 333
VAL A 280
CYH A 678
ASP A 670
 None
 0.95A 4v04B-5jxfA:
undetectable		 4v04B-5jxfA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		4 / 8 GLY A 635
ALA A 648
THR A 570
HIS A 638
 None
 0.68A 5eevL-5jxfA:
undetectable
5eevV-5jxfA:
undetectable		 5eevL-5jxfA:
7.11
5eevV-5jxfA:
7.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		4 / 8 GLY A 635
ALA A 648
THR A 570
HIS A 638
 None
 0.68A 5eewL-5jxfA:
undetectable
5eewV-5jxfA:
undetectable		 5eewL-5jxfA:
7.11
5eewV-5jxfA:
7.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		4 / 8 GLY A 635
ALA A 648
THR A 570
HIS A 638
 None
 0.68A 5eezL-5jxfA:
undetectable
5eezV-5jxfA:
undetectable		 5eezL-5jxfA:
7.11
5eezV-5jxfA:
7.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		4 / 8 GLY A 635
ALA A 648
THR A 570
HIS A 638
 None
 0.68A 5ef1L-5jxfA:
undetectable
5ef1V-5jxfA:
undetectable		 5ef1L-5jxfA:
7.11
5ef1V-5jxfA:
7.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		4 / 8 GLY A 635
ALA A 648
THR A 570
HIS A 638
 None
 0.68A 5ef2L-5jxfA:
undetectable
5ef2V-5jxfA:
undetectable		 5ef2L-5jxfA:
7.11
5ef2V-5jxfA:
7.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_L_TRPL101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		4 / 8 GLY A 635
ALA A 648
THR A 570
HIS A 638
 None
 0.68A 5ef3L-5jxfA:
undetectable
5ef3V-5jxfA:
undetectable		 5ef3L-5jxfA:
7.11
5ef3V-5jxfA:
7.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_2
(RIBOFLAVIN
TRANSPORTER RIBU)		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		3 / 3 LYS A 203
ASP A 209
ILE A 691
 ARG  A 801 ( 4.5A)
None
None
 0.91A 5kc4E-5jxfA:
2.8		 5kc4E-5jxfA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_C_SUEC1203_0
(NS3 PROTEASE)		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		5 / 12 HIS A  83
ASP A 219
GLY A 642
SER A 644
VAL A 663
 ARG  A 801 (-3.6A)
None
ASP  A 802 (-3.8A)
ASP  A 802 (-2.5A)
None
 0.89A 6c2mC-5jxfA:
6.1		 6c2mC-5jxfA:
7.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_0
(CYTOCHROME P450 1A1)		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		5 / 12 SER A 199
ASN A 115
PHE A 223
GLY A  85
ASP A  87
 None
 1.26A 6dwnA-5jxfA:
undetectable		 6dwnA-5jxfA:
7.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G1P_B_ACTB403_0
(ADP-RIBOSYLHYDROLASE
LIKE 2)		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		3 / 3 PHE A 560
ARG A 558
GLN A  18
 None
 1.09A 6g1pB-5jxfA:
undetectable		 6g1pB-5jxfA:
18.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GH9_A_MIXA1003_0
(UBIQUITIN
CARBOXYL-TERMINAL
HYDROLASE 15)		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		4 / 5 ASN A 210
GLY A  66
HIS A  83
ASP A 219
 ARG  A 801 (-2.9A)
None
ARG  A 801 (-3.6A)
None
 1.26A 6gh9A-5jxfA:
undetectable		 6gh9A-5jxfA:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HLP_A_GAWA1501_0
(SUBSTANCE-P
RECEPTOR,SUBSTANCE-P
RECEPTOR)		 5jxf ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Flavobacterium
psychrophilum) 		5 / 12 ILE A 154
VAL A 129
THR A 130
ILE A 133
PHE A 174
 None
 1.14A 6hlpA-5jxfA:
undetectable		 6hlpA-5jxfA:
20.29