SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jxk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DMI_A_BHSA1610_1
(NITRIC OXIDE
SYNTHASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 8 SER A 146
ARG A 551
ALA A 544
PHE A 150
 None
 1.03A 1dmiA-5jxkA:
undetectable
1dmiB-5jxkA:
undetectable		 1dmiA-5jxkA:
20.36
1dmiB-5jxkA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MEI_A_MOAA600_1
(INOSINE-5'-MONOPHOSP
HATE DEHYDROGENASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 8 ILE A 344
GLU A 673
GLY A 674
ARG A 670
 None
 0.88A 1meiA-5jxkA:
undetectable		 1meiA-5jxkA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_1
(PROTEASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 10 GLY A 583
ALA A 594
VAL A 263
ILE A 689
ILE A 581
 None
 0.90A 1muiA-5jxkA:
undetectable		 1muiA-5jxkA:
8.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW3_A_SAMA500_0
(HISTONE
METHYLTRANSFERASE
DOT1L)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 12 GLY A 665
ALA A 260
PHE A 668
ASN A 640
PHE A 641
 None
 1.34A 1nw3A-5jxkA:
undetectable		 1nw3A-5jxkA:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_A_BEZA502_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 6 ASN A 295
ARG A 670
ILE A 679
GLY A 676
 None
 1.02A 1oniA-5jxkA:
undetectable
1oniB-5jxkA:
undetectable		 1oniA-5jxkA:
12.52
1oniB-5jxkA:
12.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_D_BEZD508_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 6 ASN A 295
ARG A 670
ILE A 679
GLY A 676
 None
 1.09A 1oniD-5jxkA:
undetectable
1oniF-5jxkA:
undetectable		 1oniD-5jxkA:
12.52
1oniF-5jxkA:
12.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_A_SAMA801_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 6 ARG A 660
TYR A 630
ASP A 701
GLU A 662
 None
 1.24A 1rjdA-5jxkA:
undetectable		 1rjdA-5jxkA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_B_SAMB802_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 6 ARG A 660
TYR A 630
ASP A 701
GLU A 662
 None
 1.26A 1rjdB-5jxkA:
undetectable		 1rjdB-5jxkA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RJD_C_SAMC803_1
(CARBOXY METHYL
TRANSFERASE FOR
PROTEIN PHOSPHATASE
2A CATALYTIC SUBUNIT)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 6 ARG A 660
TYR A 630
ASP A 701
GLU A 662
 None
 1.26A 1rjdC-5jxkA:
undetectable		 1rjdC-5jxkA:
20.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDV_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 11 GLY A 583
ALA A 594
VAL A 263
ILE A 689
ILE A 581
 None
 0.81A 1sdvB-5jxkA:
undetectable		 1sdvB-5jxkA:
9.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WU8_C_ADNC502_1
(HYPOTHETICAL PROTEIN
PH0463)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 7 PHE A 668
ASN A  83
ASN A 651
VAL A 656
 None
 1.20A 1wu8A-5jxkA:
undetectable
1wu8C-5jxkA:
undetectable		 1wu8A-5jxkA:
18.32
1wu8C-5jxkA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YMX_A_CFXA1001_2
(BETA-LACTAMASE
CTX-M-9)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 5 CYH A 706
TYR A 101
PRO A 204
SER A 108
 None
 1.14A 1ymxA-5jxkA:
undetectable		 1ymxA-5jxkA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_A_SALA2006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 6 ARG A 694
VAL A 639
LEU A 598
ALA A 631
 CL  A 801 (-3.8A)
None
CL  A 802 (-4.9A)
None
 1.06A 2e1qA-5jxkA:
3.3		 2e1qA-5jxkA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E1Q_C_SALC4006_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 6 ARG A 694
VAL A 639
LEU A 598
ALA A 631
 CL  A 801 (-3.8A)
None
CL  A 802 (-4.9A)
None
 1.04A 2e1qC-5jxkA:
undetectable		 2e1qC-5jxkA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 12 GLU A 712
ILE A 693
LEU A 666
SER A  75
ILE A 713
 None
 1.28A 2e7fA-5jxkA:
undetectable		 2e7fA-5jxkA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 7 VAL A 122
LEU A  73
PHE A 230
THR A  82
 None
 1.14A 2f78A-5jxkA:
undetectable		 2f78A-5jxkA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1004_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 7 VAL A 122
LEU A  73
PHE A 230
THR A  82
 None
 1.12A 2f78B-5jxkA:
undetectable		 2f78B-5jxkA:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_1
(POL POLYPROTEIN)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 12 GLY A 583
ALA A 594
VAL A 263
ILE A 689
ILE A 581
 None
 1.03A 2f81A-5jxkA:
undetectable		 2f81A-5jxkA:
8.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_2
(POL POLYPROTEIN)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 12 GLY A 583
ALA A 594
VAL A 263
ILE A 689
ILE A 581
 None
 0.96A 2f81B-5jxkA:
undetectable		 2f81B-5jxkA:
8.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_2
(PROTEASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 12 GLY A 583
ALA A 594
VAL A 263
ILE A 689
ILE A 581
 None
 0.94A 2ienB-5jxkA:
undetectable		 2ienB-5jxkA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 12 GLU A 712
ILE A 693
LEU A 666
SER A  75
ILE A 713
 None
 1.30A 2ogyA-5jxkA:
undetectable		 2ogyA-5jxkA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OGY_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 12 GLU A 712
ILE A 693
LEU A 666
SER A  75
ILE A 713
 None
 1.34A 2ogyB-5jxkA:
undetectable		 2ogyB-5jxkA:
16.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_A_KLNA1501_1
(CYTOCHROME P450 3A4)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 10 ASP A 678
ARG A 670
ILE A 690
ILE A 581
GLY A  23
 None
 1.37A 2v0mA-5jxkA:
1.8		 2v0mA-5jxkA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_K_CSCK1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 12 LEU A 666
ARG A 660
GLN A 716
PHE A 641
VAL A 263
 None
 1.39A 2vavK-5jxkA:
0.0		 2vavK-5jxkA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAV_K_CSCK1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 12 LEU A 696
ARG A 660
GLN A 716
PHE A 641
VAL A 263
 None
 1.40A 2vavK-5jxkA:
0.0		 2vavK-5jxkA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_G_CSCG1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 12 LEU A 666
ARG A 660
GLN A 716
PHE A 641
VAL A 263
 None
 1.25A 2vaxG-5jxkA:
undetectable		 2vaxG-5jxkA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_G_CSCG1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 12 LEU A 696
ARG A 660
GLN A 716
PHE A 641
VAL A 263
 None
 1.41A 2vaxG-5jxkA:
undetectable		 2vaxG-5jxkA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_H_CSCH1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 12 LEU A 666
ARG A 660
GLN A 716
PHE A 641
VAL A 263
 None
 1.37A 2vaxH-5jxkA:
undetectable		 2vaxH-5jxkA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_H_CSCH1383_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 12 LEU A 696
ARG A 660
GLN A 716
PHE A 641
VAL A 263
 None
 1.49A 2vaxH-5jxkA:
undetectable		 2vaxH-5jxkA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VAX_K_CSCK1385_1
(ACETYL-COA--DEACETYL
CEPHALOSPORIN C
ACETYLTRANSFERASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 12 LEU A 666
ARG A 660
GLN A 716
PHE A 641
VAL A 263
 None
 1.17A 2vaxK-5jxkA:
undetectable		 2vaxK-5jxkA:
21.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_A_ASDA1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 8 TYR A 462
ILE A 400
ARG A 392
LEU A 535
 None
 0.88A 2vctA-5jxkA:
2.9		 2vctA-5jxkA:
14.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_A_FUAA2002_1
(SERUM ALBUMIN)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 9 ILE A  50
PHE A 268
ALA A 659
GLU A 662
 None
 0.64A 2vufA-5jxkA:
3.2		 2vufA-5jxkA:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A2Q_A_ACAA602_1
(6-AMINOHEXANOATE-CYC
LIC-DIMER HYDROLASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 7 ALA A 526
ALA A 525
ALA A 529
GLN A 436
 None
 0.82A 3a2qA-5jxkA:
undetectable		 3a2qA-5jxkA:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 7 ILE A 700
LEU A 697
THR A  82
LEU A  81
 None
 0.83A 3ablA-5jxkA:
2.1
3ablJ-5jxkA:
undetectable		 3ablA-5jxkA:
18.80
3ablJ-5jxkA:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 8 ILE A 700
LEU A 697
THR A  82
LEU A  81
 None
 0.77A 3asnN-5jxkA:
2.0
3asnW-5jxkA:
undetectable		 3asnN-5jxkA:
18.80
3asnW-5jxkA:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_2
(PHOSPHOLIPASE A2)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 6 VAL A 589
VAL A 590
ARG A 587
ARG A 687
 None
 1.04A 3bjwF-5jxkA:
undetectable		 3bjwF-5jxkA:
10.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYX_A_ROCA201_2
(HIV-1 PROTEASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		3 / 3 ARG A 386
VAL A 376
THR A 283
 None
 0.58A 3cyxA-5jxkA:
undetectable		 3cyxA-5jxkA:
8.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_1
(HIV-1 PROTEASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 12 GLY A 583
ALA A 594
VAL A 263
ILE A 689
ILE A 581
 None
 1.01A 3d20A-5jxkA:
undetectable		 3d20A-5jxkA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_A_THHA401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 12 LEU A  81
LEU A  80
ASN A  83
THR A 647
THR A  70
 None
 1.25A 3dcjA-5jxkA:
undetectable
3dcjB-5jxkA:
undetectable		 3dcjA-5jxkA:
16.25
3dcjB-5jxkA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_B_478B200_2
(PROTEASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 10 ALA A 594
VAL A 263
ILE A 689
ALA A 269
ILE A 581
 None
 0.88A 3ekpB-5jxkA:
undetectable		 3ekpB-5jxkA:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_1
(PROTEASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 10 ALA A 594
VAL A 263
ILE A 689
ALA A 269
ILE A 581
 None
 0.96A 3ekpC-5jxkA:
undetectable		 3ekpC-5jxkA:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_2
(PROTEASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 9 ALA A 594
VAL A 263
ILE A 689
ALA A 269
ILE A 581
 None
 1.00A 3ektB-5jxkA:
undetectable		 3ektB-5jxkA:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_2
(PROTEASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 11 GLY A 583
ALA A 594
VAL A 263
ILE A 689
ILE A 581
 None
 1.00A 3ektD-5jxkA:
undetectable		 3ektD-5jxkA:
8.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EQM_A_ASDA601_1
(CYTOCHROME P450 19A1)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 10 ILE A 699
PHE A 698
ASP A 615
VAL A 601
MET A 637
 None
 1.31A 3eqmA-5jxkA:
undetectable		 3eqmA-5jxkA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_1
(HIV-1 PROTEASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 12 GLY A 583
ALA A 594
VAL A 263
ILE A 689
ILE A 581
 None
 0.98A 3lzuA-5jxkA:
undetectable		 3lzuA-5jxkA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MWS_B_017B201_1
(HIV-1 PROTEASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 12 GLY A 583
ALA A 594
VAL A 263
ILE A 689
ILE A 581
 None
 1.03A 3mwsA-5jxkA:
undetectable		 3mwsA-5jxkA:
8.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_2
(PROTEASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 12 GLY A 583
ALA A 594
VAL A 263
ILE A 689
ILE A 581
 None
 0.90A 3ndtD-5jxkA:
undetectable		 3ndtD-5jxkA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_2
(PROTEASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 11 GLY A 583
ALA A 594
VAL A 263
ILE A 689
ILE A 581
 None
 0.85A 3nu3B-5jxkA:
undetectable		 3nu3B-5jxkA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_2
(PROTEASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 10 GLY A 583
ALA A 594
VAL A 263
ILE A 689
ILE A 581
 None
 0.89A 3nu6B-5jxkA:
undetectable		 3nu6B-5jxkA:
8.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_2
(PROTEASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 9 GLY A 583
ALA A 594
VAL A 263
ILE A 689
ILE A 581
 None
 0.94A 3nujB-5jxkA:
undetectable		 3nujB-5jxkA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUO_B_478B478_2
(PROTEASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 9 GLY A 583
ALA A 594
VAL A 263
ILE A 689
ILE A 581
 None
 0.93A 3nuoB-5jxkA:
undetectable		 3nuoB-5jxkA:
8.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_1
(PROTEASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 12 GLY A 583
ALA A 594
VAL A 263
ILE A 689
ILE A 581
 None
 0.93A 3oxcA-5jxkA:
undetectable		 3oxcA-5jxkA:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_2
(PROTEASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 12 GLY A 583
ALA A 594
VAL A 263
ILE A 689
ILE A 581
 None
 0.94A 3tkgD-5jxkA:
undetectable		 3tkgD-5jxkA:
11.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VKX_A_T3A301_1
(PROLIFERATING CELL
NUCLEAR ANTIGEN)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 6 MET A  28
LEU A 574
PRO A 275
TYR A 274
 None
 1.41A 3vkxA-5jxkA:
undetectable		 3vkxA-5jxkA:
18.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A99_D_MIYD393_1
(TETX2 PROTEIN)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 5 ILE A 128
GLN A  29
ILE A  31
TYR A  51
 None
 1.23A 4a99D-5jxkA:
undetectable		 4a99D-5jxkA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_A_ZMRA1471_1
(NEURAMINIDASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 12 GLU A 286
LEU A 349
ALA A 340
ASN A 295
ARG A 390
 None
 1.47A 4cpzA-5jxkA:
undetectable		 4cpzA-5jxkA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_B_ZMRB1471_1
(NEURAMINIDASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 12 GLU A 286
LEU A 349
ALA A 340
ASN A 295
ARG A 390
 None
 1.49A 4cpzB-5jxkA:
undetectable		 4cpzB-5jxkA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_D_ZMRD1471_1
(NEURAMINIDASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 12 GLU A 286
LEU A 349
ALA A 340
ASN A 295
ARG A 390
 None
 1.43A 4cpzD-5jxkA:
undetectable		 4cpzD-5jxkA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E47_D_SAMD800_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 10 ILE A 690
ALA A 643
GLU A 580
GLY A 593
TRP A 220
 None
 1.48A 4e47D-5jxkA:
1.3		 4e47D-5jxkA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_F_ASWF101_1
(DNA TOPOISOMERASE
2-BETA)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 6 PRO A 655
GLY A 661
ALA A  61
GLN A 261
 None
 1.10A 4g0uA-5jxkA:
undetectable		 4g0uA-5jxkA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0V_D_MIXD101_1
(DNA TOPOISOMERASE
2-BETA)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 6 ARG A 336
GLY A 339
ASN A 296
GLN A 686
 None
 1.27A 4g0vB-5jxkA:
undetectable		 4g0vB-5jxkA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_A_SAMA407_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 8 GLU A 662
ILE A 664
ASP A 267
ILE A 581
 None
 0.90A 4ndnB-5jxkA:
undetectable		 4ndnB-5jxkA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NDN_C_SAMC405_1
(S-ADENOSYLMETHIONINE
SYNTHASE ISOFORM
TYPE-2)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 8 GLU A 662
ILE A 664
ASP A 267
ILE A 581
 None
 0.92A 4ndnD-5jxkA:
undetectable		 4ndnD-5jxkA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OK1_A_198A1001_1
(ANDROGEN RECEPTOR)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 12 LEU A 232
GLY A  78
VAL A  62
ILE A 713
VAL A 258
 None
 1.01A 4ok1A-5jxkA:
undetectable		 4ok1A-5jxkA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OKW_A_198A1001_1
(ANDROGEN RECEPTOR)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 12 LEU A 232
GLY A  78
VAL A  62
ILE A 713
VAL A 258
 None
 1.02A 4okwA-5jxkA:
undetectable		 4okwA-5jxkA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_2
(HIV-1 PROTEASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 9 GLY A 583
ALA A 594
VAL A 263
ILE A 689
ILE A 581
 None
 0.91A 4rvjB-5jxkA:
undetectable		 4rvjB-5jxkA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_2
(HIV-1 PROTEASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 9 GLY A 583
ALA A 594
VAL A 263
ILE A 689
ILE A 581
 None
 0.91A 4rvjD-5jxkA:
undetectable		 4rvjD-5jxkA:
8.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RZV_A_032A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 5 ILE A 271
VAL A 656
PHE A 227
HIS A 646
 None
 1.06A 4rzvA-5jxkA:
2.1		 4rzvA-5jxkA:
17.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 6 LEU A 232
LEU A 120
ILE A 229
PHE A 230
 None
 1.24A 4y4dA-5jxkA:
undetectable		 4y4dA-5jxkA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZXI_A_GLYA1402_0
(TYROCIDINE
SYNTHETASE 3)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 7 ILE A 679
GLY A 676
THR A 278
TRP A 290
 None
 1.11A 4zxiA-5jxkA:
undetectable		 4zxiA-5jxkA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 7 ILE A 700
LEU A 697
THR A  82
LEU A  81
 None
 0.78A 5b1bA-5jxkA:
1.9
5b1bJ-5jxkA:
undetectable		 5b1bA-5jxkA:
18.80
5b1bJ-5jxkA:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 8 PHE A 230
ALA A 202
LEU A  79
LEU A  80
 None
 1.06A 5dzkF-5jxkA:
undetectable
5dzkT-5jxkA:
undetectable		 5dzkF-5jxkA:
17.41
5dzkT-5jxkA:
3.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_A_PAUA602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 7 GLY A 105
SER A 206
TYR A  88
ALA A 203
 None
 0.88A 5e26A-5jxkA:
undetectable
5e26B-5jxkA:
undetectable		 5e26A-5jxkA:
19.57
5e26B-5jxkA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 7 GLY A 105
SER A 206
GLY A 209
TYR A  88
ALA A 203
 None
 1.27A 5e26C-5jxkA:
undetectable
5e26D-5jxkA:
undetectable		 5e26C-5jxkA:
19.57
5e26D-5jxkA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_D_PAUD601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 8 TYR A  88
ALA A 203
GLY A 105
SER A 206
 None
 0.91A 5e26C-5jxkA:
undetectable
5e26D-5jxkA:
undetectable		 5e26C-5jxkA:
19.57
5e26D-5jxkA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 7 ILE A 700
LEU A 697
THR A  82
LEU A  81
 None
 0.83A 5iy5A-5jxkA:
0.3
5iy5J-5jxkA:
undetectable		 5iy5A-5jxkA:
18.80
5iy5J-5jxkA:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 11 ILE A 699
PHE A 698
ASP A 615
VAL A 601
MET A 637
 None
 1.29A 5jkwA-5jxkA:
undetectable		 5jkwA-5jxkA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JKW_A_TESA601_1
(AROMATASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 11 ILE A 699
PHE A 698
ASP A 615
VAL A 601
VAL A 639
 None
 1.43A 5jkwA-5jxkA:
undetectable		 5jkwA-5jxkA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JL7_A_ASDA601_1
(AROMATASE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 10 ILE A 699
PHE A 698
ASP A 615
VAL A 601
MET A 637
 None
 1.29A 5jl7A-5jxkA:
undetectable		 5jl7A-5jxkA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB603_1
(PHIAB6 TAILSPIKE)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		3 / 3 VAL A 308
GLU A 405
GLU A 450
 None
 0.78A 5jsdB-5jxkA:
undetectable
5jsdC-5jxkA:
undetectable		 5jsdB-5jxkA:
20.74
5jsdC-5jxkA:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_0
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 12 ASP A 126
ILE A 124
PRO A 240
PHE A 195
ARG A 196
 None
 1.26A 5k7uA-5jxkA:
undetectable		 5k7uA-5jxkA:
16.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M54_E_TA1E502_1
(TUBULIN BETA-2B
CHAIN)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 12 ASP A  89
HIS A  85
SER A 228
THR A 648
GLY A  67
 None
 1.01A 5m54E-5jxkA:
undetectable		 5m54E-5jxkA:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYE_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 12 LEU A 666
ALA A 202
SER A 108
ARG A 708
GLY A  78
 None
 1.04A 5syeB-5jxkA:
undetectable		 5syeB-5jxkA:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 6 ARG A 254
LYS A  59
LEU A  58
PHE A 576
 None
 1.06A 5w97C-5jxkA:
1.9
5w97J-5jxkA:
undetectable		 5w97C-5jxkA:
14.94
5w97J-5jxkA:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 7 ILE A 700
LEU A 697
THR A  82
LEU A  81
 None
 0.75A 5xdqA-5jxkA:
2.1
5xdqJ-5jxkA:
undetectable		 5xdqA-5jxkA:
18.80
5xdqJ-5jxkA:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 8 ILE A 700
LEU A 697
THR A  82
LEU A  81
 None
 0.80A 5xdxN-5jxkA:
2.0
5xdxW-5jxkA:
undetectable		 5xdxN-5jxkA:
18.80
5xdxW-5jxkA:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 8 ILE A 700
LEU A 697
THR A  82
LEU A  81
 None
 0.81A 5zcoA-5jxkA:
2.8
5zcoJ-5jxkA:
undetectable		 5zcoA-5jxkA:
18.80
5zcoJ-5jxkA:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 8 ILE A 700
LEU A 697
THR A  82
LEU A  81
 None
 0.80A 5zcqN-5jxkA:
1.4
5zcqW-5jxkA:
undetectable		 5zcqN-5jxkA:
18.80
5zcqW-5jxkA:
5.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQ4_A_ADNA401_1
(THERMOSPERMINE
SYNTHASE ACAULIS
PROTEIN)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		5 / 12 GLY A 399
VAL A 528
LEU A 458
ALA A 455
LEU A 305
 None
 0.93A 6bq4A-5jxkA:
undetectable		 6bq4A-5jxkA:
8.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		3 / 3 ARG A 254
LEU A  58
PHE A 576
 None
 0.76A 6nknP-5jxkA:
3.1		 6nknP-5jxkA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5jxk ASP/GLU-SPECIFIC
DIPEPTIDYL-PEPTIDASE
(Porphyromonas
endodontalis) 		4 / 5 ILE A 700
LEU A 697
THR A  82
LEU A  81
 None
 0.93A 6nmpN-5jxkA:
1.7
6nmpW-5jxkA:
undetectable		 6nmpN-5jxkA:
18.80
6nmpW-5jxkA:
5.46