SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jxm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_CCSA381_0
(ESTROGEN RECEPTOR)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		4 / 5 HIS A  90
GLU A 387
ALA A 385
SER A 383
 None
 1.06A 1errA-5jxmA:
undetectable
1errB-5jxmA:
undetectable		 1errA-5jxmA:
21.88
1errB-5jxmA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_CCSB381_0
(ESTROGEN RECEPTOR)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		3 / 3 GLU A 387
ALA A 385
SER A 383
 None
 0.71A 1errB-5jxmA:
undetectable		 1errB-5jxmA:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GWR_A_ESTA600_1
(OESTROGEN RECEPTOR)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		5 / 10 LEU A 223
LEU A 182
LEU A 152
HIS A 205
LEU A 200
 None
 1.34A 1gwrA-5jxmA:
undetectable		 1gwrA-5jxmA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_A_KANA558_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		4 / 7 SER A  82
ASP A 119
GLU A 112
GLU A  94
 None
None
None
TRS  A 501 (-2.1A)
 1.11A 1knyA-5jxmA:
undetectable
1knyB-5jxmA:
undetectable		 1knyA-5jxmA:
21.57
1knyB-5jxmA:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_A_SALA710_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		4 / 7 VAL A 233
LEU A 223
ALA A 199
LEU A 200
 None
 0.78A 1pthA-5jxmA:
undetectable		 1pthA-5jxmA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PTH_B_SALB711_1
(PROSTAGLANDIN H2
SYNTHASE-1)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		4 / 7 VAL A 233
LEU A 223
ALA A 199
LEU A 200
 None
 0.78A 1pthB-5jxmA:
undetectable		 1pthB-5jxmA:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UYU_B_CAMB1416_0
(CYTOCHROME P450-CAM)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		4 / 8 THR A 143
LEU A 225
VAL A 178
ASP A 137
 None
 1.05A 1uyuB-5jxmA:
undetectable		 1uyuB-5jxmA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRC_A_CAMA420_0
(CYTOCHROME P450-CAM)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		4 / 7 THR A 143
LEU A 225
VAL A 178
ASP A 137
 None
 1.04A 1yrcA-5jxmA:
undetectable		 1yrcA-5jxmA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YRD_A_CAMA420_0
(CYTOCHROME P450-CAM)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		4 / 7 THR A 143
LEU A 225
VAL A 178
ASP A 137
 None
 1.03A 1yrdA-5jxmA:
undetectable		 1yrdA-5jxmA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWT_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		4 / 7 THR A 143
LEU A 225
VAL A 178
ASP A 137
 None
 1.03A 2zwtA-5jxmA:
undetectable		 2zwtA-5jxmA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZWU_A_CAMA422_0
(CAMPHOR
5-MONOOXYGENASE)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		4 / 7 THR A 143
LEU A 225
VAL A 178
ASP A 137
 None
 1.04A 2zwuA-5jxmA:
undetectable		 2zwuA-5jxmA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		4 / 5 GLN A 261
PHE A 265
LEU A 333
PHE A  99
 None
 1.36A 3ablC-5jxmA:
undetectable
3ablJ-5jxmA:
undetectable		 3ablC-5jxmA:
21.17
3ablJ-5jxmA:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DFR_A_MTXA164_1
(DIHYDROFOLATE
REDUCTASE)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		5 / 12 LEU A 203
ALA A 208
LEU A 212
PRO A 219
ALA A 199
 None
 1.08A 3dfrA-5jxmA:
undetectable		 3dfrA-5jxmA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWF_B_CAMB420_0
(CAMPHOR
5-MONOOXYGENASE)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		4 / 7 THR A 143
LEU A 225
VAL A 178
ASP A 137
 None
 1.04A 3fwfB-5jxmA:
undetectable		 3fwfB-5jxmA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FWJ_A_CAMA420_0
(CAMPHOR
5-MONOOXYGENASE)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		4 / 7 THR A 143
LEU A 225
VAL A 178
ASP A 137
 None
 1.05A 3fwjA-5jxmA:
undetectable		 3fwjA-5jxmA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_C_SAMC301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		5 / 12 ARG A 267
THR A 268
ASP A 322
ILE A 362
LEU A 365
 None
 1.30A 3iv6C-5jxmA:
undetectable		 3iv6C-5jxmA:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_A_CAMA423_0
(CYTOCHROME P450)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		5 / 10 THR A  91
LEU A  35
GLY A  36
VAL A 111
VAL A  93
 None
 0.84A 3lxiA-5jxmA:
undetectable		 3lxiA-5jxmA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LXI_B_CAMB423_0
(CYTOCHROME P450)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		5 / 11 THR A  91
LEU A  35
GLY A  36
VAL A 111
VAL A  93
 None
 0.84A 3lxiB-5jxmA:
undetectable		 3lxiB-5jxmA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SP9_B_IL2B901_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR DELTA)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		5 / 12 LEU A 203
VAL A 233
LEU A 212
HIS A 312
TYR A 380
 None
None
None
None
TRS  A 501 ( 4.5A)
 1.31A 3sp9B-5jxmA:
undetectable		 3sp9B-5jxmA:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRH_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		4 / 7 THR A 143
LEU A 225
VAL A 178
ASP A 137
 None
 1.03A 3wrhA-5jxmA:
undetectable		 3wrhA-5jxmA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRJ_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		4 / 7 THR A 143
LEU A 225
VAL A 178
ASP A 137
 None
 1.05A 3wrjA-5jxmA:
undetectable		 3wrjA-5jxmA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRL_A_CAMA503_0
(CAMPHOR
5-MONOOXYGENASE)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		4 / 7 THR A 143
LEU A 225
VAL A 178
ASP A 137
 None
 1.03A 3wrlA-5jxmA:
undetectable		 3wrlA-5jxmA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WRM_F_CAMF503_0
(CAMPHOR
5-MONOOXYGENASE)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		4 / 7 THR A 143
LEU A 225
VAL A 178
ASP A 137
 None
 1.03A 3wrmF-5jxmA:
undetectable		 3wrmF-5jxmA:
20.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9K_B_CAMB424_0
(CYTOCHROME P450)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		5 / 9 THR A  91
LEU A  35
GLY A  36
VAL A 111
VAL A  93
 None
 0.78A 4c9kB-5jxmA:
undetectable		 4c9kB-5jxmA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_A_CAMA1419_0
(CYTOCHROME P450)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		5 / 12 THR A  91
LEU A  35
GLY A  36
VAL A 111
VAL A  93
 None
 0.82A 4c9lA-5jxmA:
undetectable		 4c9lA-5jxmA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9L_B_CAMB1419_0
(CYTOCHROME P450)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		5 / 12 THR A  91
LEU A  35
GLY A  36
VAL A 111
VAL A  93
 None
 0.82A 4c9lB-5jxmA:
undetectable		 4c9lB-5jxmA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_B_CAMB1420_0
(CYTOCHROME P450)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		5 / 10 THR A  91
LEU A  35
GLY A  36
VAL A 111
VAL A  93
 None
 0.80A 4c9nB-5jxmA:
undetectable		 4c9nB-5jxmA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_A_CAMA423_0
(CYTOCHROME P450)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		5 / 12 THR A  91
LEU A  35
GLY A  36
VAL A 111
VAL A  93
 None
 0.79A 4c9oA-5jxmA:
undetectable		 4c9oA-5jxmA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9O_B_CAMB423_0
(CYTOCHROME P450)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		5 / 12 THR A  91
LEU A  35
GLY A  36
VAL A 111
VAL A  93
 None
 0.81A 4c9oB-5jxmA:
undetectable		 4c9oB-5jxmA:
23.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_A_CAMA423_0
(CYTOCHROME P450)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		5 / 9 THR A  91
LEU A  35
GLY A  36
VAL A 111
VAL A  93
 None
 0.82A 4c9pA-5jxmA:
undetectable		 4c9pA-5jxmA:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9P_B_CAMB423_0
(CYTOCHROME P450)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		5 / 10 THR A  91
LEU A  35
GLY A  36
VAL A 111
VAL A  93
 None
 0.84A 4c9pB-5jxmA:
undetectable		 4c9pB-5jxmA:
24.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_2
(SUGAR KINASE)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		3 / 3 SER A  96
TYR A 380
PRO A 105
 None
TRS  A 501 ( 4.5A)
None
 0.92A 4k8cA-5jxmA:
undetectable		 4k8cA-5jxmA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		3 / 3 SER A  96
TYR A 380
PRO A 105
 None
TRS  A 501 ( 4.5A)
None
 0.88A 4kahA-5jxmA:
undetectable		 4kahA-5jxmA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		3 / 3 SER A  96
TYR A 380
PRO A 105
 None
TRS  A 501 ( 4.5A)
None
 0.89A 4kahB-5jxmA:
undetectable		 4kahB-5jxmA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		3 / 3 SER A  96
TYR A 380
PRO A 105
 None
TRS  A 501 ( 4.5A)
None
 0.91A 4kanA-5jxmA:
undetectable		 4kanA-5jxmA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		3 / 3 SER A  96
TYR A 380
PRO A 105
 None
TRS  A 501 ( 4.5A)
None
 0.92A 4kanB-5jxmA:
undetectable		 4kanB-5jxmA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		3 / 3 SER A  96
TYR A 380
PRO A 105
 None
TRS  A 501 ( 4.5A)
None
 0.92A 4kbeA-5jxmA:
undetectable		 4kbeA-5jxmA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		3 / 3 SER A  96
TYR A 380
PRO A 105
 None
TRS  A 501 ( 4.5A)
None
 0.90A 4kbeB-5jxmA:
undetectable		 4kbeB-5jxmA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		3 / 3 SER A  96
TYR A 380
PRO A 105
 None
TRS  A 501 ( 4.5A)
None
 0.91A 4lbgA-5jxmA:
undetectable		 4lbgA-5jxmA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		3 / 3 SER A  96
TYR A 380
PRO A 105
 None
TRS  A 501 ( 4.5A)
None
 0.89A 4lbgB-5jxmA:
undetectable		 4lbgB-5jxmA:
23.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		4 / 5 ASN A 183
ALA A 185
GLY A 160
ASP A 317
 None
 1.00A 4n48A-5jxmA:
undetectable		 4n48A-5jxmA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RTB_A_SAMA501_1
(HYDG PROTEIN)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		3 / 3 GLU A 300
ARG A 371
GLN A 207
 None
 0.86A 4rtbA-5jxmA:
undetectable		 4rtbA-5jxmA:
23.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_K_CHDK103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		5 / 11 ALA A  39
LEU A  43
LEU A 168
ARG A 108
LEU A 170
 None
None
None
TRS  A 501 ( 4.7A)
None
 1.24A 4wg0I-5jxmA:
undetectable
4wg0J-5jxmA:
undetectable
4wg0K-5jxmA:
undetectable		 4wg0I-5jxmA:
4.86
4wg0J-5jxmA:
4.86
4wg0K-5jxmA:
4.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y0P_A_TE4A201_1
(BETA-LACTOGLOBULIN)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		5 / 12 LEU A  46
VAL A  49
VAL A 379
VAL A 377
PHE A  99
 None
 1.14A 4y0pA-5jxmA:
2.1		 4y0pA-5jxmA:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		4 / 7 LEU A  35
PRO A  81
LEU A  76
TYR A 386
 None
 0.99A 4z4fA-5jxmA:
undetectable		 4z4fA-5jxmA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_F_SORF1342_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		4 / 4 ARG A 371
HIS A 205
ALA A 208
GLU A 300
 None
 1.33A 5a06A-5jxmA:
undetectable
5a06F-5jxmA:
0.4		 5a06A-5jxmA:
20.93
5a06F-5jxmA:
20.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5T7B_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		4 / 7 LEU A  35
PRO A  81
LEU A  76
TYR A 386
 None
 0.92A 5t7bA-5jxmA:
undetectable		 5t7bA-5jxmA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		4 / 6 LEU A 164
PHE A 153
PHE A 154
LEU A 129
 None
 1.16A 5x19P-5jxmA:
undetectable		 5x19P-5jxmA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9Y_A_ACTA412_0
(UNCHARACTERIZED
PROTEIN KDOO)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		3 / 3 ARG A 316
PHE A  85
ARG A 290
 TRS  A 501 ( 4.5A)
TRS  A 501 (-3.9A)
None
 1.16A 5y9yA-5jxmA:
undetectable		 5y9yA-5jxmA:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		5 / 10 ARG A 197
VAL A 196
ALA A 193
LEU A 200
LEU A 237
 None
 0.99A 6f5uA-5jxmA:
undetectable
6f5uB-5jxmA:
undetectable		 6f5uA-5jxmA:
12.03
6f5uB-5jxmA:
12.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_C_CHDC307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		4 / 6 GLN A 261
PHE A 265
LEU A 333
PHE A  99
 None
 1.26A 6nmpC-5jxmA:
undetectable
6nmpJ-5jxmA:
undetectable		 6nmpC-5jxmA:
21.17
6nmpJ-5jxmA:
9.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_A_BEZA701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		5 / 11 GLY A 285
LEU A 287
ALA A 292
ALA A 247
PHE A 266
 None
 1.47A 6qgbA-5jxmA:
undetectable		 6qgbA-5jxmA:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6QGB_E_BEZE701_0
(MONO(2-HYDROXYETHYL)
TEREPHTHALATE
HYDROLASE)		 5jxm PRIB
(Streptomyces
sp.
RM-5-8) 		5 / 11 GLY A 285
LEU A 287
ALA A 292
ALA A 247
PHE A 266
 None
 1.45A 6qgbE-5jxmA:
undetectable		 6qgbE-5jxmA:
24.06