SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jxt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_1
(ESTROGEN RECEPTOR)		 5jxt CHROMATIN-REMODELING
COMPLEX ATPASE-LIKE
PROTEIN
(Thermothelomyces
thermophila) 		5 / 12 THR B 566
ALA B 596
ASP B 593
LEU B 575
ILE B 561
 None
 1.25A 1errA-5jxtB:
undetectable		 1errA-5jxtB:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FSL_B_NIOB145_1
(LEGHEMOGLOBIN A)		 5jxt CHROMATIN-REMODELING
COMPLEX ATPASE-LIKE
PROTEIN
(Thermothelomyces
thermophila) 		4 / 8 PHE B 560
TYR B 531
ILE B 561
VAL B 509
 None
 0.69A 1fslB-5jxtB:
undetectable		 1fslB-5jxtB:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G10_A_ACTA301_0
(GLUTATHIONE
S-TRANSFERASE
HOMOLOG)		 5jxt CHROMATIN-REMODELING
COMPLEX ATPASE-LIKE
PROTEIN
(Thermothelomyces
thermophila) 		4 / 6 ILE B 502
TYR B 525
TYR B 531
PHE B 560
 None
 1.23A 4g10A-5jxtB:
undetectable		 4g10A-5jxtB:
21.69