SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jxx'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_1
(HIV-1 PROTEASE)		 5jxx ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Moraxella
catarrhalis) 		5 / 10 LEU A 112
ALA A  61
ILE A  45
GLY A  64
ILE A  87
 None
 0.99A 1hsgA-5jxxA:
undetectable		 1hsgA-5jxxA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_2
(HIV-II PROTEASE)		 5jxx ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Moraxella
catarrhalis) 		5 / 9 ALA A  13
ILE A  33
ILE A  26
ILE A   3
ILE A  15
 None
 0.94A 1hshB-5jxxA:
undetectable		 1hshB-5jxxA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_1
(POL POLYPROTEIN)		 5jxx ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Moraxella
catarrhalis) 		5 / 10 LEU A 112
ALA A  61
ILE A  45
GLY A  46
GLY A  64
 None
 1.01A 1k6cA-5jxxA:
undetectable		 1k6cA-5jxxA:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AZY_A_CHDA237_0
(PHOSPHOLIPASE A2,
MAJOR ISOENZYME)		 5jxx ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Moraxella
catarrhalis) 		5 / 11 ILE A  81
ILE A  63
HIS A  94
GLY A 125
LEU A 112
 None
 1.15A 2azyA-5jxxA:
undetectable		 2azyA-5jxxA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM0_A_CHDA151_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5jxx ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Moraxella
catarrhalis) 		5 / 10 ILE A   3
ILE A   9
LYS A  29
GLY A  28
LEU A  39
 None
 1.17A 3em0A-5jxxA:
undetectable		 3em0A-5jxxA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXW_B_017B200_2
(HIV-1 PROTEASE)		 5jxx ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Moraxella
catarrhalis) 		5 / 10 LEU A 112
ALA A  61
ILE A  45
GLY A  64
ILE A  87
 None
 1.02A 3oxwB-5jxxA:
undetectable		 3oxwB-5jxxA:
15.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RET_A_SALA201_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 5jxx ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Moraxella
catarrhalis) 		5 / 10 VAL A 134
ALA A 140
VAL A 124
ILE A 118
ILE A 148
 None
 1.38A 3retA-5jxxA:
undetectable
3retB-5jxxA:
undetectable		 3retA-5jxxA:
16.80
3retB-5jxxA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S45_B_478B201_1
(PROTEASE)		 5jxx ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Moraxella
catarrhalis) 		5 / 9 ALA A  13
ILE A  33
ILE A   8
ILE A   3
ILE A  15
 None
 1.00A 3s45A-5jxxA:
undetectable		 3s45A-5jxxA:
15.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVD_A_SAMA502_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 5jxx ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Moraxella
catarrhalis) 		5 / 12 ILE A 142
ALA A 177
HIS A 145
VAL A 146
ILE A 148
 None
 1.00A 4rvdA-5jxxA:
undetectable		 4rvdA-5jxxA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 5jxx ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Moraxella
catarrhalis) 		5 / 11 ILE A  45
ILE A  51
VAL A  27
ILE A  15
ALA A  19
 None
 0.84A 5lg3A-5jxxA:
undetectable		 5lg3A-5jxxA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_E_Z80E401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 5jxx ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Moraxella
catarrhalis) 		5 / 12 ILE A  45
ILE A  51
VAL A  27
ILE A  15
ALA A  19
 None
 0.86A 5lg3E-5jxxA:
undetectable		 5lg3E-5jxxA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0F_B_DAHB98_0
(MELC
TYROSINASE)		 5jxx ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Moraxella
catarrhalis) 		5 / 11 ASN A  55
VAL A  38
SER A  18
HIS A  54
ASP A  56
 None
 1.47A 5z0fA-5jxxA:
undetectable
5z0fB-5jxxA:
undetectable		 5z0fA-5jxxA:
14.74
5z0fB-5jxxA:
13.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z0G_B_DAHB98_0
(MELC
TYROSINASE)		 5jxx ACYL-[ACYL-CARRIER-P
ROTEIN]--UDP-N-ACETY
LGLUCOSAMINE
O-ACYLTRANSFERASE
(Moraxella
catarrhalis) 		5 / 11 ASN A  55
VAL A  38
SER A  18
HIS A  54
ASP A  56
 None
 1.50A 5z0gA-5jxxA:
undetectable
5z0gB-5jxxA:
undetectable		 5z0gA-5jxxA:
14.74
5z0gB-5jxxA:
13.51