SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jy5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3003_1
(SERUM ALBUMIN)		 5jy5 THIOREDOXIN
(Cryptococcus
neoformans) 		4 / 6 ILE A  84
LYS A 101
ALA A 104
VAL A  20
 None
 1.00A 1hk1A-5jy5A:
undetectable		 1hk1A-5jy5A:
10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OS6_A_DXCA75_0
(PPCA)		 5jy5 THIOREDOXIN
(Cryptococcus
neoformans) 		4 / 8 ILE A  95
LEU A  99
PHE A  52
GLY A  45
 None
 1.05A 1os6A-5jy5A:
undetectable		 1os6A-5jy5A:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SJ1_X_DXCX75_0
(CYTOCHROME C7)		 5jy5 THIOREDOXIN
(Cryptococcus
neoformans) 		4 / 6 ILE A  95
LEU A  99
PHE A  52
GLY A  45
 None
 0.95A 3sj1X-5jy5A:
undetectable		 3sj1X-5jy5A:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W68_B_VIVB301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5jy5 THIOREDOXIN
(Cryptococcus
neoformans) 		5 / 12 ILE A  69
VAL A  20
ILE A  95
LEU A  99
VAL A  50
 None
 1.10A 3w68B-5jy5A:
undetectable		 3w68B-5jy5A:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HBF_A_DXCA75_0
(PPCA)		 5jy5 THIOREDOXIN
(Cryptococcus
neoformans) 		4 / 7 ILE A  95
LEU A  99
PHE A  52
GLY A  45
 None
 0.97A 4hbfA-5jy5A:
undetectable		 4hbfA-5jy5A:
18.42