SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jy7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G72_A_SAMA2001_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)		 5jy7 MALTOKINASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 THR I 313
LEU I 236
VAL I 243
HIS I 244
ALA I 173
 None
 1.41A 2g72A-5jy7I:
undetectable		 2g72A-5jy7I:
22.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A65_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5jy7 MALTOKINASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 MET I 192
ASP I 321
SER I 132
ASN I 133
GLY I 191
 None
 1.31A 3a65A-5jy7I:
undetectable		 3a65A-5jy7I:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VWP_A_ACAA503_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5jy7 MALTOKINASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 MET I 192
ASP I 321
SER I 132
ASN I 133
GLY I 191
 None
 1.33A 3vwpA-5jy7I:
undetectable		 3vwpA-5jy7I:
24.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VWR_A_ACAA601_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5jy7 MALTOKINASE
(Mycolicibacteriu
m
smegmatis) 		5 / 11 MET I 192
ASP I 321
SER I 132
ASN I 133
GLY I 191
 None
 1.32A 3vwrA-5jy7I:
undetectable		 3vwrA-5jy7I:
24.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_B_MRVB1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 5jy7 MALTOKINASE
(Mycolicibacteriu
m
smegmatis) 		4 / 5 TYR I  15
THR I 181
LEU I 190
THR I 134
 None
 1.40A 4mbsB-5jy7I:
undetectable		 4mbsB-5jy7I:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MBS_B_MRVB1101_2
(CHIMERA PROTEIN OF
C-C CHEMOKINE
RECEPTOR TYPE 5 AND
RUBREDOXIN)		 5jy7 MALTOKINASE
(Mycolicibacteriu
m
smegmatis) 		4 / 5 TYR I  83
THR I 181
LEU I 190
THR I 134
 None
 1.47A 4mbsB-5jy7I:
undetectable		 4mbsB-5jy7I:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UAC_A_ACRA501_2
(CARBOHYDRATE ABC
TRANSPORTER
SUBSTRATE-BINDING
PROTEIN, CUT1 FAMILY
(TC 3.A.1.1.-))		 5jy7 MALTOKINASE
(Mycolicibacteriu
m
smegmatis) 		4 / 7 GLU I 232
TRP I 379
ASP I 213
THR I 209
 None
 1.24A 4uacA-5jy7I:
undetectable		 4uacA-5jy7I:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_K_IPHK101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 5jy7 MALTOKINASE
(Mycolicibacteriu
m
smegmatis) 		4 / 6 VAL I 243
HIS I 244
HIS I 302
LEU I 160
 None
 1.47A 5hrqH-5jy7I:
undetectable
5hrqK-5jy7I:
undetectable
5hrqL-5jy7I:
undetectable		 5hrqH-5jy7I:
6.51
5hrqK-5jy7I:
4.09
5hrqL-5jy7I:
6.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_F_SAMF501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 5jy7 MALTOKINASE
(Mycolicibacteriu
m
smegmatis) 		5 / 10 LEU I 319
GLU I 232
GLY I 203
ARG I 235
ALA I 239
 None
 1.09A 5o96E-5jy7I:
undetectable
5o96F-5jy7I:
undetectable		 5o96E-5jy7I:
21.75
5o96F-5jy7I:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XV7_A_EMHA705_1
(SERINE-ARGININE (SR)
PROTEIN KINASE 1)		 5jy7 MALTOKINASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU I 176
GLY I 177
VAL I 193
ALA I 142
PHE I 138
 None
 0.49A 5xv7A-5jy7I:
9.2		 5xv7A-5jy7I:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_A_RFPA502_1
(RIFAMPIN
MONOOXYGENASE)		 5jy7 MALTOKINASE
(Mycolicibacteriu
m
smegmatis) 		5 / 12 HIS I 302
VAL I 172
PHE I 322
MET I 192
GLY I 324
 None
 1.41A 6brdA-5jy7I:
undetectable		 6brdA-5jy7I:
12.02