SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jy9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Q_A_BEZA1501_0
(ANTHRANILATE
SYNTHASE)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		9 / 11 GLU A 240
GLY A 257
THR A 258
GLU A 284
HIS A 321
ARG A 391
GLY A 407
GLU A 420
LYS A 424
 None
ACT  A 503 (-3.2A)
ACT  A 503 (-3.7A)
FE2  A 501 ( 2.7A)
ACT  A 503 ( 4.1A)
ACT  A 502 (-3.5A)
ACT  A 503 (-3.8A)
FE2  A 501 ( 2.8A)
ACT  A 503 ( 2.3A)
 0.28A 1i7qA-5jy9A:
42.6		 1i7qA-5jy9A:
28.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Q_A_BEZA1501_0
(ANTHRANILATE
SYNTHASE)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		5 / 11 GLY A 257
THR A 258
HIS A 321
LEU A 388
ARG A 391
 ACT  A 503 (-3.2A)
ACT  A 503 (-3.7A)
ACT  A 503 ( 4.1A)
None
ACT  A 502 (-3.5A)
 1.16A 1i7qA-5jy9A:
42.6		 1i7qA-5jy9A:
28.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I7Q_C_BEZC1502_0
(ANTHRANILATE
SYNTHASE)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		9 / 10 GLU A 240
GLY A 257
THR A 258
GLU A 284
HIS A 321
ARG A 391
GLY A 407
GLU A 420
LYS A 424
 None
ACT  A 503 (-3.2A)
ACT  A 503 (-3.7A)
FE2  A 501 ( 2.7A)
ACT  A 503 ( 4.1A)
ACT  A 502 (-3.5A)
ACT  A 503 (-3.8A)
FE2  A 501 ( 2.8A)
ACT  A 503 ( 2.3A)
 0.26A 1i7qC-5jy9A:
42.3		 1i7qC-5jy9A:
28.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J8U_A_H4BA429_1
(PHENYLALANINE-4-HYDR
OXYLASE)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		4 / 7 VAL A 222
LEU A 388
LEU A 241
ALA A 292
 None
 0.84A 1j8uA-5jy9A:
undetectable		 1j8uA-5jy9A:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JU6_C_LYAC315_1
(THYMIDYLATE SYNTHASE)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		5 / 10 ILE A  76
ASN A  54
GLY A  99
PHE A 102
ALA A 113
 None
 1.42A 1ju6C-5jy9A:
undetectable		 1ju6C-5jy9A:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_0
(MODIFICATION
METHYLASE RSRI)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		5 / 12 TRP A 337
GLY A 374
SER A 373
ALA A 386
ALA A 387
 None
 1.24A 1nw5A-5jy9A:
undetectable		 1nw5A-5jy9A:
21.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FN1_A_SALA506_1
(SALICYLATE
SYNTHETASE, IRP9)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		11 / 11 ILE A 195
GLU A 240
GLY A 257
THR A 258
GLU A 284
HIS A 321
LEU A 390
ARG A 391
GLY A 407
GLU A 420
LYS A 424
 ACT  A 502 ( 4.8A)
None
ACT  A 503 (-3.2A)
ACT  A 503 (-3.7A)
FE2  A 501 ( 2.7A)
ACT  A 503 ( 4.1A)
ACT  A 502 (-3.5A)
ACT  A 502 (-3.5A)
ACT  A 503 (-3.8A)
FE2  A 501 ( 2.8A)
ACT  A 503 ( 2.3A)
 0.23A 2fn1A-5jy9A:
72.8		 2fn1A-5jy9A:
99.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FN1_B_SALB503_1
(SALICYLATE
SYNTHETASE, IRP9)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		7 / 11 GLY A 257
THR A 258
GLU A 281
HIS A 321
ARG A 391
GLU A 420
LYS A 424
 ACT  A 503 (-3.2A)
ACT  A 503 (-3.7A)
FE2  A 501 ( 4.1A)
ACT  A 503 ( 4.1A)
ACT  A 502 (-3.5A)
FE2  A 501 ( 2.8A)
ACT  A 503 ( 2.3A)
 1.50A 2fn1B-5jy9A:
70.7		 2fn1B-5jy9A:
99.77
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2FN1_B_SALB503_1
(SALICYLATE
SYNTHETASE, IRP9)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		11 / 11 ILE A 195
GLU A 240
GLY A 257
THR A 258
GLU A 284
HIS A 321
THR A 348
ARG A 391
GLY A 407
GLU A 420
LYS A 424
 ACT  A 502 ( 4.8A)
None
ACT  A 503 (-3.2A)
ACT  A 503 (-3.7A)
FE2  A 501 ( 2.7A)
ACT  A 503 ( 4.1A)
None
ACT  A 502 (-3.5A)
ACT  A 503 (-3.8A)
FE2  A 501 ( 2.8A)
ACT  A 503 ( 2.3A)
 0.34A 2fn1B-5jy9A:
70.7		 2fn1B-5jy9A:
99.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_E_SC2E1291_1
(FICOLIN-2)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		4 / 4 ASP A 309
LEU A 255
GLY A 323
ARG A 316
 None
 1.38A 2j2pD-5jy9A:
undetectable
2j2pE-5jy9A:
undetectable		 2j2pD-5jy9A:
17.23
2j2pE-5jy9A:
17.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZM9_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		5 / 9 ALA A 406
TYR A 175
ILE A 408
GLY A 407
ILE A 195
 None
None
None
ACT  A 503 (-3.8A)
ACT  A 502 ( 4.8A)
 1.28A 2zm9A-5jy9A:
undetectable		 2zm9A-5jy9A:
24.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_H_LFXH0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		4 / 6 ARG A  92
GLY A  46
GLU A 230
GLU A  31
 None
 0.97A 3k9fA-5jy9A:
1.0
3k9fB-5jy9A:
1.1
3k9fD-5jy9A:
undetectable		 3k9fA-5jy9A:
22.75
3k9fB-5jy9A:
22.75
3k9fD-5jy9A:
20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OEZ_A_STIA601_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		4 / 5 LYS A 193
VAL A 282
ILE A 409
ARG A 314
 None
 1.39A 3oezA-5jy9A:
undetectable		 3oezA-5jy9A:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA270_0
(PROTEIN SSM1)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		4 / 5 LEU A 213
ARG A  25
LEU A  17
PRO A  18
 None
 1.27A 3onnA-5jy9A:
undetectable		 3onnA-5jy9A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		8 / 12 GLU A 240
GLY A 257
THR A 258
GLU A 284
HIS A 321
ARG A 391
GLU A 420
LYS A 424
 None
ACT  A 503 (-3.2A)
ACT  A 503 (-3.7A)
FE2  A 501 ( 2.7A)
ACT  A 503 ( 4.1A)
ACT  A 502 (-3.5A)
FE2  A 501 ( 2.8A)
ACT  A 503 ( 2.3A)
 0.44A 3r75A-5jy9A:
43.6		 3r75A-5jy9A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		5 / 12 GLY A 257
THR A 258
HIS A 321
ARG A 391
THR A 348
 ACT  A 503 (-3.2A)
ACT  A 503 (-3.7A)
ACT  A 503 ( 4.1A)
ACT  A 502 (-3.5A)
None
 1.12A 3r75A-5jy9A:
43.6		 3r75A-5jy9A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		8 / 12 GLU A 240
GLY A 257
THR A 258
GLU A 284
HIS A 321
ARG A 391
GLU A 420
LYS A 424
 None
ACT  A 503 (-3.2A)
ACT  A 503 (-3.7A)
FE2  A 501 ( 2.7A)
ACT  A 503 ( 4.1A)
ACT  A 502 (-3.5A)
FE2  A 501 ( 2.8A)
ACT  A 503 ( 2.3A)
 0.43A 3r75B-5jy9A:
43.4		 3r75B-5jy9A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		5 / 12 GLY A 257
THR A 258
HIS A 321
ARG A 391
THR A 348
 ACT  A 503 (-3.2A)
ACT  A 503 (-3.7A)
ACT  A 503 ( 4.1A)
ACT  A 502 (-3.5A)
None
 1.10A 3r75B-5jy9A:
43.4		 3r75B-5jy9A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R76_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		8 / 11 GLU A 240
GLY A 257
THR A 258
GLU A 284
HIS A 321
ARG A 391
GLU A 420
LYS A 424
 None
ACT  A 503 (-3.2A)
ACT  A 503 (-3.7A)
FE2  A 501 ( 2.7A)
ACT  A 503 ( 4.1A)
ACT  A 502 (-3.5A)
FE2  A 501 ( 2.8A)
ACT  A 503 ( 2.3A)
 0.45A 3r76A-5jy9A:
43.5		 3r76A-5jy9A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R76_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		5 / 11 GLY A 257
THR A 258
HIS A 321
ARG A 391
THR A 348
 ACT  A 503 (-3.2A)
ACT  A 503 (-3.7A)
ACT  A 503 ( 4.1A)
ACT  A 502 (-3.5A)
None
 1.18A 3r76A-5jy9A:
43.5		 3r76A-5jy9A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R76_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		8 / 11 GLU A 240
GLY A 257
THR A 258
GLU A 284
HIS A 321
ARG A 391
GLU A 420
LYS A 424
 None
ACT  A 503 (-3.2A)
ACT  A 503 (-3.7A)
FE2  A 501 ( 2.7A)
ACT  A 503 ( 4.1A)
ACT  A 502 (-3.5A)
FE2  A 501 ( 2.8A)
ACT  A 503 ( 2.3A)
 0.47A 3r76B-5jy9A:
43.4		 3r76B-5jy9A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R76_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		5 / 11 GLY A 257
THR A 258
HIS A 321
ARG A 391
THR A 348
 ACT  A 503 (-3.2A)
ACT  A 503 (-3.7A)
ACT  A 503 ( 4.1A)
ACT  A 502 (-3.5A)
None
 1.16A 3r76B-5jy9A:
43.4		 3r76B-5jy9A:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_G_ACTG306_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		3 / 3 ARG A 125
ARG A  92
ASP A  64
 None
 0.96A 3wipG-5jy9A:
undetectable
3wipH-5jy9A:
undetectable		 3wipG-5jy9A:
20.14
3wipH-5jy9A:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_ACTA860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		4 / 5 GLY A 407
ILE A 409
VAL A 179
SER A 412
 ACT  A 503 (-3.8A)
None
None
None
 0.92A 4d33A-5jy9A:
undetectable		 4d33A-5jy9A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		4 / 5 GLY A 407
ILE A 409
VAL A 179
SER A 412
 ACT  A 503 (-3.8A)
None
None
None
 0.94A 4d33B-5jy9A:
undetectable		 4d33B-5jy9A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D39_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		4 / 6 GLY A 407
ILE A 409
VAL A 179
SER A 412
 ACT  A 503 (-3.8A)
None
None
None
 0.97A 4d39B-5jy9A:
undetectable		 4d39B-5jy9A:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_B_ASWB1301_1
(DNA TOPOISOMERASE
2-BETA)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		4 / 7 ILE A 347
GLY A 405
ALA A 256
GLN A 178
 None
ACT  A 502 (-3.4A)
ACT  A 503 (-4.8A)
None
 0.85A 4g0uB-5jy9A:
undetectable		 4g0uB-5jy9A:
18.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_D_MXMD606_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		5 / 12 VAL A 166
ILE A 428
VAL A 393
LEU A 432
TRP A 116
 None
 1.37A 4m11D-5jy9A:
undetectable		 4m11D-5jy9A:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWV_A_BCZA513_1
(NEURAMINIDASE)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		3 / 3 ARG A 223
GLU A 253
ARG A 383
 None
 0.76A 4mwvA-5jy9A:
undetectable		 4mwvA-5jy9A:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V20_A_ACTA1444_0
(CELLOBIOHYDROLASE)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		4 / 5 GLY A 257
THR A 258
GLY A 407
GLU A 281
 ACT  A 503 (-3.2A)
ACT  A 503 (-3.7A)
ACT  A 503 (-3.8A)
FE2  A 501 ( 4.1A)
 0.79A 4v20A-5jy9A:
undetectable		 4v20A-5jy9A:
20.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_A_HFGA702_1
(AMINOACYL-TRNA
SYNTHETASE)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		4 / 4 THR A 348
GLU A 240
THR A 258
HIS A 321
 None
None
ACT  A 503 (-3.7A)
ACT  A 503 ( 4.1A)
 1.48A 5f9zA-5jy9A:
undetectable		 5f9zA-5jy9A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_A_SAMA801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		5 / 12 ILE A  53
GLY A  57
THR A  58
ALA A  60
LEU A  51
 None
 1.23A 5hw4A-5jy9A:
undetectable		 5hw4A-5jy9A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW4_C_SAMC801_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE I)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		5 / 12 ILE A  53
GLY A  57
THR A  58
ALA A  60
LEU A  51
 None
 1.20A 5hw4C-5jy9A:
undetectable		 5hw4C-5jy9A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_A_ADNA401_1
(ADENOSINE KINASE)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		6 / 12 THR A 258
VAL A 319
ILE A 428
ALA A 404
GLY A 405
HIS A 321
 ACT  A 503 (-3.7A)
None
None
ACT  A 502 (-3.8A)
ACT  A 502 (-3.4A)
ACT  A 503 ( 4.1A)
 1.44A 5kb6A-5jy9A:
undetectable		 5kb6A-5jy9A:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_E_CVIE301_1
(REGULATORY PROTEIN
TETR)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		4 / 7 GLN A  26
GLY A  22
GLN A 395
ASP A 207
 None
 1.09A 5vlmE-5jy9A:
undetectable		 5vlmE-5jy9A:
19.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA503_1
(CYTOCHROME P450 2C9)		 5jy9 PUTATIVE SALICYLATE
SYNTHETASE
(Yersinia
enterocolitica) 		5 / 12 LEU A 371
LEU A 212
PRO A 209
THR A 211
LEU A 432
 None
 1.27A 5xxiA-5jy9A:
undetectable		 5xxiA-5jy9A:
21.74