SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jyj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_A_CHDA1502_0
(FERROCHELATASE)		 5jyj SPERM-EGG FUSION
PROTEIN JUNO
(Mus
musculus) 		5 / 8 MET A  28
PRO A 105
VAL A 123
GLY A 122
TRP A 106
 None
 1.36A 1hrkA-5jyjA:
undetectable		 1hrkA-5jyjA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_A_CHDA502_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5jyj SPERM-EGG FUSION
PROTEIN JUNO
(Mus
musculus) 		4 / 5 MET A  28
PRO A 105
VAL A 123
TRP A 106
 None
 1.48A 2pnjA-5jyjA:
0.0		 2pnjA-5jyjA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA502_0
(FERROCHELATASE)		 5jyj SPERM-EGG FUSION
PROTEIN JUNO
(Mus
musculus) 		4 / 8 MET A  28
VAL A 123
GLY A 122
TRP A 106
 None
 0.99A 2qd3A-5jyjA:
undetectable		 2qd3A-5jyjA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_A_ACTA603_0
(CHOLINE OXIDASE)		 5jyj SPERM-EGG FUSION
PROTEIN JUNO
(Mus
musculus) 		3 / 3 ARG A 199
HIS A 219
SER A 197
 None
 0.86A 4mjwA-5jyjA:
undetectable
4mjwB-5jyjA:
undetectable		 4mjwA-5jyjA:
15.38
4mjwB-5jyjA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_B_ACTB603_0
(CHOLINE OXIDASE)		 5jyj SPERM-EGG FUSION
PROTEIN JUNO
(Mus
musculus) 		3 / 3 SER A 197
ARG A 199
HIS A 219
 None
 0.86A 4mjwA-5jyjA:
undetectable
4mjwB-5jyjA:
undetectable		 4mjwA-5jyjA:
15.38
4mjwB-5jyjA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OGC_B_TA1B601_1
(TUBULIN BETA CHAIN)		 5jyj SPERM-EGG FUSION
PROTEIN JUNO
(Mus
musculus) 		5 / 12 VAL A 216
PHE A  96
THR A 187
GLY A 104
LEU A 103
 None
 1.14A 5ogcB-5jyjA:
undetectable		 5ogcB-5jyjA:
18.87