SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jym'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1H8S_A_AICA1000_1
(MUTANT AL2 6E7P9G)		 5jym ANTIBODY SCFV TSP11
(Mus
musculus) 		10 / 12 TYR B 178
GLN B 231
TYR B 236
PHE B 240
TRP B  33
ASN B  35
VAL B  37
ASN B  50
ALA B  97
TRP B 112
 None
 0.63A 1h8sA-5jymB:
12.8		 1h8sA-5jymB:
40.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_A_NOVA400_2
(DNA GYRASE SUBUNIT B)		 5jym ANTIBODY SCFV TSP11
(Mus
musculus) 		3 / 3 ASN B  56
PHE B  29
VAL B  72
 None
 0.84A 1kijA-5jymB:
undetectable		 1kijA-5jymB:
18.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_A_PNXA1435_1
(CHITINASE)		 5jym ANTIBODY SCFV TSP11
(Mus
musculus) 		4 / 6 TYR B 236
GLY B 173
SER B 171
ARG B 192
 None
 1.18A 2a3cA-5jymB:
undetectable		 2a3cA-5jymB:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3C_B_PNXB2434_1
(CHITINASE)		 5jym ANTIBODY SCFV TSP11
(Mus
musculus) 		4 / 6 TYR B 236
GLY B 173
SER B 171
ARG B 192
 None
 1.22A 2a3cB-5jymB:
undetectable		 2a3cB-5jymB:
20.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FSU_A_C2FA995_0
(5,10-METHYLENETETRAH
YDROFOLATE REDUCTASE)		 5jym ANTIBODY SCFV TSP11
(Mus
musculus) 		5 / 12 GLN B   6
GLN B  82
LEU B  20
THR B 116
LEU B  70
 None
 1.40A 3fsuA-5jymB:
undetectable		 3fsuA-5jymB:
20.59
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 5jym ANTIBODY SCFV TSP11
(Mus
musculus) 		4 / 5 VAL B   2
TYR B  27
ARG B  98
TYR B 111
 None
 0.34A 4m7kH-5jymB:
22.2		 4m7kH-5jymB:
49.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UMD_A_YMZA3801_1
(60S RIBOSOMAL
PROTEIN L28
28S RIBOSOMAL RNA
60S RIBOSOMAL
PROTEIN L4)		 5jym ANTIBODY SCFV TSP11
(Mus
musculus) 		4 / 6 ASN B  77
ALA B  24
PRO B  53
TYR B  27
 None
 1.08A 5umd2-5jymB:
undetectable
5umdF-5jymB:
undetectable		 5umd2-5jymB:
13.62
5umdF-5jymB:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDH_C_DAHC60_1
(PUTATIVE CYTOCHROME
C)		 5jym ANTIBODY SCFV TSP11
(Mus
musculus) 		4 / 6 MET B  81
ASN B  77
VAL B  72
LEU B  70
 None
 0.97A 5xdhA-5jymB:
undetectable
5xdhC-5jymB:
undetectable		 5xdhA-5jymB:
14.92
5xdhC-5jymB:
14.92