SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jys'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_A_DVAA6_0
(GRAMICIDIN A)		 5jys PROTEIN PRY1
(Saccharomyces
cerevisiae) 		3 / 3 ALA A 225
VAL A 227
TRP A 230
 None
 0.91A 1nt5A-5jysA:
undetectable		 1nt5A-5jysA:
5.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_B_DVAB6_0
(GRAMICIDIN A)		 5jys PROTEIN PRY1
(Saccharomyces
cerevisiae) 		3 / 3 ALA A 225
VAL A 227
TRP A 230
 None
 0.91A 1nt5B-5jysA:
undetectable		 1nt5B-5jysA:
5.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAX_A_CAMA422_0
(CYTOCHROME P450-CAM)		 5jys PROTEIN PRY1
(Saccharomyces
cerevisiae) 		4 / 7 PHE A 239
TYR A 237
VAL A 255
THR A 180
 None
 1.06A 2zaxA-5jysA:
undetectable		 2zaxA-5jysA:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EBZ_B_017B201_2
(PROTEASE)		 5jys PROTEIN PRY1
(Saccharomyces
cerevisiae) 		5 / 11 LEU A 217
ALA A 226
ASP A 222
ILE A 266
ILE A 278
 MG  A 301 (-3.9A)
None
None
None
None
 1.15A 3ebzB-5jysA:
undetectable		 3ebzB-5jysA:
14.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QA2_B_SHHB404_1
(HISTONE DEACETYLASE
8)		 5jys PROTEIN PRY1
(Saccharomyces
cerevisiae) 		5 / 12 TYR A 237
HIS A 208
GLY A 249
PHE A 244
GLY A 214
 None
MG  A 301 (-3.8A)
None
None
None
 1.13A 4qa2B-5jysA:
undetectable		 4qa2B-5jysA:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_A_DCFA401_1
(ADENOSINE DEAMINASE)		 5jys PROTEIN PRY1
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 170
LEU A 217
TYR A 276
GLY A 265
 None
MG  A 301 (-3.9A)
None
None
 1.40A 6n91A-5jysA:
undetectable		 6n91A-5jysA:
12.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6N91_B_DCFB401_1
(ADENOSINE DEAMINASE)		 5jys PROTEIN PRY1
(Saccharomyces
cerevisiae) 		4 / 4 HIS A 170
LEU A 217
TYR A 276
GLY A 265
 None
MG  A 301 (-3.9A)
None
None
 1.37A 6n91B-5jysA:
undetectable		 6n91B-5jysA:
12.08