SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jzg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU3_A_MRCA993_2
(ISOLEUCYL-TRNA
SYNTHETASE)		 5jzg CAPSID PROTEIN VP0
(Rhinovirus
C) 		4 / 4 TRP C 145
SER C  69
LYS C  94
VAL C  70
 None
 1.47A 1qu3A-5jzgC:
0.0		 1qu3A-5jzgC:
17.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILT_H_TRUH800_1
(GLUTAMATE RECEPTOR 2)		 5jzg CAPSID PROTEIN VP0
(Rhinovirus
C) 		3 / 3 ILE C 270
SER C  67
SER C  69
 None
 0.61A 3iltH-5jzgC:
undetectable		 3iltH-5jzgC:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5jzg CAPSID PROTEIN VP0
(Rhinovirus
C) 		3 / 3 ALA C 316
TYR C 130
PRO C 122
 None
 0.61A 4zdyA-5jzgC:
undetectable		 4zdyA-5jzgC:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPC_A_SAMA401_1
(PAVINE
N-METHYLTRANSFERASE)		 5jzg CAPSID PROTEIN VP0
(Rhinovirus
C) 		4 / 5 PHE C 129
SER C  87
GLN C 177
ASP C 133
 None
 1.46A 5kpcA-5jzgC:
undetectable		 5kpcA-5jzgC:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LJC_A_RTLA201_1
(RETINOL-BINDING
PROTEIN 1)		 5jzg CAPSID PROTEIN VP0
(Rhinovirus
C) 		4 / 7 LEU C 148
ILE C 311
THR C 176
TRP C 144
 None
 1.22A 5ljcA-5jzgC:
undetectable		 5ljcA-5jzgC:
15.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X2S_I_PEMI202_1
(HEMOGLOBIN SUBUNIT
ALPHA
HEMOGLOBIN SUBUNIT
BETA)		 5jzg CAPSID PROTEIN VP0
(Rhinovirus
C) 		4 / 8 PRO C 317
LYS C 319
THR C 124
TYR C 130
 None
 1.33A 5x2sI-5jzgC:
undetectable
5x2sJ-5jzgC:
undetectable
5x2sK-5jzgC:
undetectable		 5x2sI-5jzgC:
16.82
5x2sJ-5jzgC:
18.73
5x2sK-5jzgC:
16.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AWP_A_FVXA701_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5jzg CAPSID PROTEIN VP0
(Rhinovirus
C) 		5 / 9 ILE C 293
SER C 218
SER C 141
GLY C 143
THR C 176
 None
 1.48A 6awpA-5jzgC:
undetectable		 6awpA-5jzgC:
18.99