SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5jzw'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_1
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 5jzw AEROLYSIN
(Aeromonas
hydrophila) 		3 / 3 ARG A 356
ASP A 311
ASP A 180
 None
 0.84A 2ejtA-5jzwA:
undetectable		 2ejtA-5jzwA:
21.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZBZ_A_VDXA501_1
(CYTOCHROME P450-SU1)		 5jzw AEROLYSIN
(Aeromonas
hydrophila) 		5 / 11 LEU A 393
VAL A 392
SER A 354
ILE A 345
ALA A 120
 None
 1.21A 2zbzA-5jzwA:
undetectable		 2zbzA-5jzwA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C6P_A_4YHA601_1
(PROTEIN C)		 5jzw AEROLYSIN
(Aeromonas
hydrophila) 		4 / 6 ALA A 423
GLN A 212
SER A 213
PRO A 419
 None
 1.17A 5c6pA-5jzwA:
undetectable		 5c6pA-5jzwA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G08_A_Z80A1187_1
(FREQUENIN 2)		 5jzw AEROLYSIN
(Aeromonas
hydrophila) 		4 / 6 ILE A 302
PHE A 404
PHE A 410
THR A 223
 None
 1.25A 5g08A-5jzwA:
undetectable		 5g08A-5jzwA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G08_A_Z80A1187_1
(FREQUENIN 2)		 5jzw AEROLYSIN
(Aeromonas
hydrophila) 		4 / 6 ILE A 302
PHE A 404
PHE A 410
THR A 275
 None
 0.89A 5g08A-5jzwA:
undetectable		 5g08A-5jzwA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA602_1
(CHITINASE)		 5jzw AEROLYSIN
(Aeromonas
hydrophila) 		3 / 3 TRP A 359
GLU A  84
ASP A   7
 None
 0.84A 5gqbA-5jzwA:
undetectable		 5gqbA-5jzwA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HI6_A_MTXA201_1
(DIHYDROFOLATE
REDUCTASE)		 5jzw AEROLYSIN
(Aeromonas
hydrophila) 		5 / 12 ILE A 170
LEU A 123
SER A 353
ILE A 355
THR A 168
 None
 1.14A 5hi6A-5jzwA:
undetectable		 5hi6A-5jzwA:
18.56