SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5k1z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_A_ADNA1260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		5 / 10 VAL A 172
GLU A 173
MET A 174
GLU A 175
ASP A 198
 4CT  A 301 ( 4.5A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
4CT  A 301 (-2.2A)
 0.39A 1jdvA-5k1zA:
24.1
1jdvD-5k1zA:
24.1		 1jdvA-5k1zA:
23.27
1jdvD-5k1zA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_B_ADNB2260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		5 / 10 VAL A 172
GLU A 173
MET A 174
GLU A 175
ASP A 198
 4CT  A 301 ( 4.5A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
4CT  A 301 (-2.2A)
 0.36A 1jdvB-5k1zA:
23.8
1jdvC-5k1zA:
23.3		 1jdvB-5k1zA:
23.27
1jdvC-5k1zA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_D_ADND3260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		5 / 10 VAL A 172
GLU A 173
MET A 174
GLU A 175
ASP A 198
 4CT  A 301 ( 4.5A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
4CT  A 301 (-2.2A)
 0.38A 1jdvA-5k1zA:
24.1
1jdvD-5k1zA:
24.1		 1jdvA-5k1zA:
23.27
1jdvD-5k1zA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JDV_E_ADNE4260_1
(5'-METHYLTHIOADENOSI
NE PHOSPHORYLASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		7 / 12 GLY A  80
VAL A 172
GLU A 173
MET A 174
GLU A 175
SER A 197
ASP A 198
 4CT  A 301 (-3.4A)
4CT  A 301 ( 4.5A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
4CT  A 301 ( 2.8A)
4CT  A 301 (-2.2A)
 0.44A 1jdvE-5k1zA:
23.9
1jdvF-5k1zA:
23.4		 1jdvE-5k1zA:
23.27
1jdvF-5k1zA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KNY_B_KANB559_1
(KANAMYCIN
NUCLEOTIDYLTRANSFERA
SE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		4 / 8 SER A 197
ASP A 198
GLU A  13
GLU A  12
 4CT  A 301 ( 2.8A)
4CT  A 301 (-2.2A)
4CT  A 301 ( 4.5A)
None
 0.87A 1knyA-5k1zA:
undetectable
1knyB-5k1zA:
undetectable		 1knyA-5k1zA:
23.31
1knyB-5k1zA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_A_ADNA1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		5 / 11 GLY A  80
GLU A 173
MET A 174
GLU A 175
SER A 197
 4CT  A 301 (-3.4A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
4CT  A 301 ( 2.8A)
 0.35A 1odiA-5k1zA:
17.2		 1odiA-5k1zA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_B_ADNB1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		5 / 11 GLY A  80
GLU A 173
MET A 174
GLU A 175
SER A 197
 4CT  A 301 (-3.4A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
4CT  A 301 ( 2.8A)
 0.45A 1odiB-5k1zA:
25.5		 1odiB-5k1zA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_C_ADNC1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		5 / 11 GLY A  80
GLU A 173
MET A 174
GLU A 175
SER A 197
 4CT  A 301 (-3.4A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
4CT  A 301 ( 2.8A)
 0.41A 1odiC-5k1zA:
25.3		 1odiC-5k1zA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_D_ADND1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		5 / 11 GLY A  80
GLU A 173
MET A 174
GLU A 175
SER A 197
 4CT  A 301 (-3.4A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
4CT  A 301 ( 2.8A)
 0.44A 1odiD-5k1zA:
25.5		 1odiD-5k1zA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_E_ADNE1237_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		5 / 11 GLY A  80
GLU A 173
MET A 174
GLU A 175
SER A 197
 4CT  A 301 (-3.4A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
4CT  A 301 ( 2.8A)
 0.44A 1odiE-5k1zA:
25.5		 1odiE-5k1zA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ODI_F_ADNF1238_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		5 / 11 GLY A  80
GLU A 173
MET A 174
GLU A 175
SER A 197
 4CT  A 301 (-3.4A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
4CT  A 301 ( 2.8A)
 0.44A 1odiF-5k1zA:
25.3		 1odiF-5k1zA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_A_ADNA1245_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		6 / 9 GLY A  80
GLU A 173
MET A 174
GLU A 175
SER A 197
ASP A 198
 4CT  A 301 (-3.4A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
4CT  A 301 ( 2.8A)
4CT  A 301 (-2.2A)
 0.51A 1pk7A-5k1zA:
23.9		 1pk7A-5k1zA:
25.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK7_C_ADNC1247_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		7 / 10 GLY A  80
VAL A 172
GLU A 173
MET A 174
GLU A 175
SER A 197
ASP A 198
 4CT  A 301 (-3.4A)
4CT  A 301 ( 4.5A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
4CT  A 301 ( 2.8A)
4CT  A 301 (-2.2A)
 0.47A 1pk7C-5k1zA:
24.7		 1pk7C-5k1zA:
25.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_A_2FAA306_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		7 / 10 GLY A  80
VAL A 172
GLU A 173
MET A 174
GLU A 175
SER A 197
ASP A 198
 4CT  A 301 (-3.4A)
4CT  A 301 ( 4.5A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
4CT  A 301 ( 2.8A)
4CT  A 301 (-2.2A)
 0.43A 1pk9A-5k1zA:
23.8		 1pk9A-5k1zA:
25.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_B_2FAB307_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		6 / 9 GLY A  80
GLU A 173
MET A 174
GLU A 175
SER A 197
ASP A 198
 4CT  A 301 (-3.4A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
4CT  A 301 ( 2.8A)
4CT  A 301 (-2.2A)
 0.43A 1pk9B-5k1zA:
24.0		 1pk9B-5k1zA:
25.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		7 / 11 GLY A  80
VAL A 172
GLU A 173
MET A 174
GLU A 175
SER A 197
ASP A 198
 4CT  A 301 (-3.4A)
4CT  A 301 ( 4.5A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
4CT  A 301 ( 2.8A)
4CT  A 301 (-2.2A)
 0.39A 1pk9C-5k1zA:
24.8		 1pk9C-5k1zA:
25.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PK9_C_2FAC308_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		5 / 11 MET A  10
GLY A  80
GLU A 173
SER A 197
ASP A 198
 4CT  A 301 ( 2.9A)
4CT  A 301 (-3.4A)
None
4CT  A 301 ( 2.8A)
4CT  A 301 (-2.2A)
 1.16A 1pk9C-5k1zA:
24.8		 1pk9C-5k1zA:
25.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_A_RABA645_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		6 / 10 GLY A  80
GLU A 173
MET A 174
GLU A 175
SER A 197
ASP A 198
 4CT  A 301 (-3.4A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
4CT  A 301 ( 2.8A)
4CT  A 301 (-2.2A)
 0.48A 1pw7A-5k1zA:
23.9		 1pw7A-5k1zA:
25.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_B_RABB646_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		5 / 9 GLY A  80
VAL A 172
GLU A 173
MET A 174
GLU A 175
 4CT  A 301 (-3.4A)
4CT  A 301 ( 4.5A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
 0.47A 1pw7B-5k1zA:
24.2		 1pw7B-5k1zA:
25.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_C_RABC647_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		6 / 9 VAL A 172
GLU A 173
MET A 174
GLU A 175
SER A 197
ASP A 198
 4CT  A 301 ( 4.5A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
4CT  A 301 ( 2.8A)
4CT  A 301 (-2.2A)
 0.48A 1pw7C-5k1zA:
24.6		 1pw7C-5k1zA:
25.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_A_ADNA252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		5 / 11 GLY A  80
VAL A 172
GLU A 173
MET A 174
GLU A 175
 4CT  A 301 (-3.4A)
4CT  A 301 ( 4.5A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
 0.39A 1vhwA-5k1zA:
24.2
1vhwD-5k1zA:
24.1		 1vhwA-5k1zA:
22.61
1vhwD-5k1zA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_C_ADNC252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		5 / 11 GLY A  80
VAL A 172
GLU A 173
MET A 174
GLU A 175
 4CT  A 301 (-3.4A)
4CT  A 301 ( 4.5A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
 0.39A 1vhwC-5k1zA:
24.2
1vhwE-5k1zA:
24.3		 1vhwC-5k1zA:
22.61
1vhwE-5k1zA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_D_ADND252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		5 / 11 GLY A  80
VAL A 172
GLU A 173
MET A 174
GLU A 175
 4CT  A 301 (-3.4A)
4CT  A 301 ( 4.5A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
 0.39A 1vhwA-5k1zA:
24.2
1vhwD-5k1zA:
24.1		 1vhwA-5k1zA:
22.61
1vhwD-5k1zA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_E_ADNE252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		5 / 11 GLY A  80
VAL A 172
GLU A 173
MET A 174
GLU A 175
 4CT  A 301 (-3.4A)
4CT  A 301 ( 4.5A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
 0.39A 1vhwC-5k1zA:
24.2
1vhwE-5k1zA:
24.3		 1vhwC-5k1zA:
22.61
1vhwE-5k1zA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VHW_F_ADNF252_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		5 / 10 GLY A  80
VAL A 172
GLU A 173
MET A 174
GLU A 175
 4CT  A 301 (-3.4A)
4CT  A 301 ( 4.5A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
 0.40A 1vhwB-5k1zA:
24.5
1vhwF-5k1zA:
24.2		 1vhwB-5k1zA:
22.61
1vhwF-5k1zA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z35_A_2FAA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		6 / 10 GLY A  80
VAL A 172
GLU A 173
MET A 174
GLU A 175
SER A 197
 4CT  A 301 (-3.4A)
4CT  A 301 ( 4.5A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
4CT  A 301 ( 2.8A)
 0.52A 1z35A-5k1zA:
23.7		 1z35A-5k1zA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z37_A_ADNA300_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		6 / 9 GLY A  80
VAL A 172
GLU A 173
MET A 174
GLU A 175
SER A 197
 4CT  A 301 (-3.4A)
4CT  A 301 ( 4.5A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
4CT  A 301 ( 2.8A)
 0.35A 1z37A-5k1zA:
23.7		 1z37A-5k1zA:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AC7_A_ADNA1216_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		6 / 11 GLY A  80
VAL A 172
GLU A 173
MET A 174
GLU A 175
ASP A 198
 4CT  A 301 (-3.4A)
4CT  A 301 ( 4.5A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
4CT  A 301 (-2.2A)
 0.43A 2ac7A-5k1zA:
23.9
2ac7B-5k1zA:
23.9		 2ac7A-5k1zA:
21.95
2ac7B-5k1zA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AC7_B_ADNB1215_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		6 / 11 GLY A  80
VAL A 172
GLU A 173
MET A 174
GLU A 175
ASP A 198
 4CT  A 301 (-3.4A)
4CT  A 301 ( 4.5A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
4CT  A 301 (-2.2A)
 0.42A 2ac7A-5k1zA:
23.9
2ac7B-5k1zA:
23.9		 2ac7A-5k1zA:
21.95
2ac7B-5k1zA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_A_H4BA600_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		4 / 7 MET A  10
ARG A 194
ILE A  14
GLU A  12
 4CT  A 301 ( 2.9A)
4CT  A 301 ( 4.2A)
None
None
 1.47A 2nsiA-5k1zA:
undetectable
2nsiB-5k1zA:
undetectable		 2nsiA-5k1zA:
22.03
2nsiB-5k1zA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_B_H4BB601_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		4 / 7 GLU A  12
MET A  10
ARG A 194
ILE A  14
 None
4CT  A 301 ( 2.9A)
4CT  A 301 ( 4.2A)
None
 1.44A 2nsiA-5k1zA:
undetectable
2nsiB-5k1zA:
undetectable		 2nsiA-5k1zA:
22.03
2nsiB-5k1zA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_C_H4BC602_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		4 / 7 MET A  10
ARG A 194
ILE A  14
GLU A  12
 4CT  A 301 ( 2.9A)
4CT  A 301 ( 4.2A)
None
None
 1.44A 2nsiC-5k1zA:
undetectable
2nsiD-5k1zA:
undetectable		 2nsiC-5k1zA:
22.03
2nsiD-5k1zA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NSI_D_H4BD603_1
(PROTEIN (NITRIC
OXIDE SYNTHASE))		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		4 / 7 GLU A  12
MET A  10
ARG A 194
ILE A  14
 None
4CT  A 301 ( 2.9A)
4CT  A 301 ( 4.2A)
None
 1.45A 2nsiC-5k1zA:
undetectable
2nsiD-5k1zA:
undetectable		 2nsiC-5k1zA:
22.03
2nsiD-5k1zA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZT7_A_GLYA1300_0
(GLYCYL-TRNA
SYNTHETASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		4 / 7 GLU A 175
ARG A 194
GLU A 173
SER A 149
 4CT  A 301 (-2.2A)
4CT  A 301 ( 4.2A)
None
None
 1.23A 2zt7A-5k1zA:
undetectable		 2zt7A-5k1zA:
16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_A_H4BA902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		4 / 7 MET A  10
ARG A 194
ILE A  14
GLU A  12
 4CT  A 301 ( 2.9A)
4CT  A 301 ( 4.2A)
None
None
 1.47A 3e7gA-5k1zA:
undetectable
3e7gB-5k1zA:
undetectable		 3e7gA-5k1zA:
21.98
3e7gB-5k1zA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_B_H4BB1902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		4 / 7 GLU A  12
MET A  10
ARG A 194
ILE A  14
 None
4CT  A 301 ( 2.9A)
4CT  A 301 ( 4.2A)
None
 1.49A 3e7gA-5k1zA:
undetectable
3e7gB-5k1zA:
undetectable		 3e7gA-5k1zA:
21.98
3e7gB-5k1zA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_C_H4BC2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		4 / 7 MET A  10
ARG A 194
ILE A  14
GLU A  12
 4CT  A 301 ( 2.9A)
4CT  A 301 ( 4.2A)
None
None
 1.41A 3e7gC-5k1zA:
undetectable
3e7gD-5k1zA:
undetectable		 3e7gC-5k1zA:
21.98
3e7gD-5k1zA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3O7W_A_SAMA801_0
(LEUCINE CARBOXYL
METHYLTRANSFERASE 1)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		5 / 12 GLY A   8
ILE A  14
LEU A 212
GLU A 173
VAL A  78
 None
None
None
None
4CT  A 301 (-4.1A)
 1.06A 3o7wA-5k1zA:
undetectable		 3o7wA-5k1zA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PMZ_E_TUBE220_1
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		4 / 6 GLN A   2
ILE A   4
SER A 126
SER A 124
 None
 1.13A 3pmzD-5k1zA:
undetectable		 3pmzD-5k1zA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXH_A_HSMA7_1
(CATIONIC TRYPSIN)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		4 / 5 ASP A 198
SER A 197
VAL A  78
GLY A  80
 4CT  A 301 (-2.2A)
4CT  A 301 ( 2.8A)
4CT  A 301 (-4.1A)
4CT  A 301 (-3.4A)
 0.95A 3rxhA-5k1zA:
undetectable		 3rxhA-5k1zA:
19.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SMT_A_ACTA1001_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD3)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		4 / 5 LEU A 111
GLY A 112
PHE A 167
PHE A 162
 None
 1.15A 3smtA-5k1zA:
undetectable		 3smtA-5k1zA:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_C_ADNC251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		6 / 12 GLY A  80
VAL A 172
GLU A 173
MET A 174
GLU A 175
ASP A 198
 4CT  A 301 (-3.4A)
4CT  A 301 ( 4.5A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
4CT  A 301 (-2.2A)
 0.30A 3u40B-5k1zA:
24.0
3u40C-5k1zA:
23.8		 3u40B-5k1zA:
27.44
3u40C-5k1zA:
27.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_D_ADND251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		6 / 11 GLY A  80
VAL A 172
GLU A 173
MET A 174
GLU A 175
ASP A 198
 4CT  A 301 (-3.4A)
4CT  A 301 ( 4.5A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
4CT  A 301 (-2.2A)
 0.33A 3u40D-5k1zA:
24.2
3u40E-5k1zA:
23.8		 3u40D-5k1zA:
27.44
3u40E-5k1zA:
27.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_E_ADNE251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		6 / 12 GLY A  80
VAL A 172
GLU A 173
MET A 174
GLU A 175
ASP A 198
 4CT  A 301 (-3.4A)
4CT  A 301 ( 4.5A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
4CT  A 301 (-2.2A)
 0.31A 3u40D-5k1zA:
24.2
3u40E-5k1zA:
23.8		 3u40D-5k1zA:
27.44
3u40E-5k1zA:
27.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U40_F_ADNF251_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		5 / 10 VAL A 172
GLU A 173
MET A 174
GLU A 175
ASP A 198
 4CT  A 301 ( 4.5A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
4CT  A 301 (-2.2A)
 0.60A 3u40A-5k1zA:
23.9
3u40F-5k1zA:
23.5		 3u40A-5k1zA:
27.44
3u40F-5k1zA:
27.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAW_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		7 / 11 GLY A  80
VAL A 172
GLU A 173
MET A 174
GLU A 175
SER A 197
ASP A 198
 4CT  A 301 (-3.4A)
4CT  A 301 ( 4.5A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
4CT  A 301 ( 2.8A)
4CT  A 301 (-2.2A)
 0.38A 3uawA-5k1zA:
24.6		 3uawA-5k1zA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UAY_A_ADNA236_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		5 / 10 GLY A  80
VAL A 172
GLU A 173
MET A 174
GLU A 175
 4CT  A 301 (-3.4A)
4CT  A 301 ( 4.5A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
 0.42A 3uayA-5k1zA:
24.5		 3uayA-5k1zA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6D_A_SAMA1350_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		5 / 12 LEU A 212
GLY A  77
ILE A  14
PHE A  75
ALA A  79
 None
None
None
None
4CT  A 301 (-4.5A)
 1.15A 4a6dA-5k1zA:
undetectable		 4a6dA-5k1zA:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_A_T1CA392_1
(TETX2 PROTEIN)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		5 / 11 PHE A 208
ASN A 199
GLY A 205
ALA A 216
MET A  10
 4CT  A 301 (-3.5A)
None
None
None
4CT  A 301 ( 2.9A)
 1.34A 4a6nA-5k1zA:
undetectable		 4a6nA-5k1zA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		6 / 11 GLY A  80
VAL A 172
GLU A 173
MET A 174
GLU A 175
SER A 197
 4CT  A 301 (-3.4A)
4CT  A 301 ( 4.5A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
4CT  A 301 ( 2.8A)
 0.36A 4d9hA-5k1zA:
25.0		 4d9hA-5k1zA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		5 / 11 GLY A  80
VAL A 172
MET A 174
SER A 197
ASP A 198
 4CT  A 301 (-3.4A)
4CT  A 301 ( 4.5A)
4CT  A 301 (-3.0A)
4CT  A 301 ( 2.8A)
4CT  A 301 (-2.2A)
 0.75A 4d9hA-5k1zA:
25.0		 4d9hA-5k1zA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA6_A_GA2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		5 / 9 GLY A  80
VAL A 172
MET A 174
GLU A 175
SER A 197
 4CT  A 301 (-3.4A)
4CT  A 301 ( 4.5A)
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
4CT  A 301 ( 2.8A)
 0.61A 4da6A-5k1zA:
24.6		 4da6A-5k1zA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA6_A_GA2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		5 / 9 GLY A  80
VAL A 172
MET A 174
SER A 197
ASP A 198
 4CT  A 301 (-3.4A)
4CT  A 301 ( 4.5A)
4CT  A 301 (-3.0A)
4CT  A 301 ( 2.8A)
4CT  A 301 (-2.2A)
 0.90A 4da6A-5k1zA:
24.6		 4da6A-5k1zA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DA7_A_AC2A301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		6 / 10 GLY A  80
VAL A 172
GLU A 173
MET A 174
GLU A 175
SER A 197
 4CT  A 301 (-3.4A)
4CT  A 301 ( 4.5A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
4CT  A 301 ( 2.8A)
 0.43A 4da7A-5k1zA:
25.0		 4da7A-5k1zA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_A_2FAA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		7 / 11 GLY A  80
VAL A 172
GLU A 173
MET A 174
GLU A 175
SER A 197
ASP A 198
 4CT  A 301 (-3.4A)
4CT  A 301 ( 4.5A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
4CT  A 301 ( 2.8A)
4CT  A 301 (-2.2A)
 0.67A 4danA-5k1zA:
24.6		 4danA-5k1zA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DAN_B_2FAB301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		7 / 12 GLY A  80
VAL A 172
GLU A 173
MET A 174
GLU A 175
SER A 197
ASP A 198
 4CT  A 301 (-3.4A)
4CT  A 301 ( 4.5A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
4CT  A 301 ( 2.8A)
4CT  A 301 (-2.2A)
 0.67A 4danA-5k1zA:
24.6
4danB-5k1zA:
24.7		 4danA-5k1zA:
20.99
4danB-5k1zA:
20.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR3_A_GLYA701_0
(GLYCINE--TRNA LIGASE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		4 / 6 GLU A 175
ARG A 194
GLU A 173
SER A 149
 4CT  A 301 (-2.2A)
4CT  A 301 ( 4.2A)
None
None
 1.13A 4kr3A-5k1zA:
undetectable		 4kr3A-5k1zA:
17.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NED_A_PFNA709_1
(LACTOTRANSFERRIN)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		4 / 6 ASP A  90
VAL A  83
ASP A  85
ALA A 141
 None
 1.10A 4nedA-5k1zA:
undetectable		 4nedA-5k1zA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_B_AC2B301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		5 / 10 GLY A  80
VAL A 172
GLU A 173
MET A 174
GLU A 175
 4CT  A 301 (-3.4A)
4CT  A 301 ( 4.5A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
 0.44A 5i3cB-5k1zA:
24.4		 5i3cB-5k1zA:
25.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I3C_C_AC2C301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 5k1z AMINODEOXYFUTALOSINE
NUCLEOSIDASE
(Helicobacter
pylori) 		6 / 11 GLY A  80
VAL A 172
GLU A 173
MET A 174
GLU A 175
SER A 197
 4CT  A 301 (-3.4A)
4CT  A 301 ( 4.5A)
None
4CT  A 301 (-3.0A)
4CT  A 301 (-2.2A)
4CT  A 301 ( 2.8A)
 0.45A 5i3cC-5k1zA:
24.0		 5i3cC-5k1zA:
25.50