SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5k21'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2D55_C_DVAC2_0
(ACTINOMYCIN D)		 5k21 PYOCYANIN
DEMETHYLASE
(Mycolicibacteriu
m
fortuitum) 		3 / 3 THR A  94
PRO A  98
PRO A  95
 None
 0.89A 2d55C-5k21A:
undetectable		 2d55C-5k21A:
6.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1001_1
(HEMOLYTIC LECTIN
CEL-III)		 5k21 PYOCYANIN
DEMETHYLASE
(Mycolicibacteriu
m
fortuitum) 		4 / 5 ASP A  63
VAL A  64
GLY A  65
ASP A  56
 CA  A 202 (-3.0A)
None
None
CA  A 202 (-3.1A)
 1.26A 3w9tA-5k21A:
undetectable		 3w9tA-5k21A:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB503_1
(HEMOLYTIC LECTIN
CEL-III)		 5k21 PYOCYANIN
DEMETHYLASE
(Mycolicibacteriu
m
fortuitum) 		4 / 5 ASP A  63
VAL A  64
GLY A  65
ASP A  56
 CA  A 202 (-3.0A)
None
None
CA  A 202 (-3.1A)
 1.24A 3w9tB-5k21A:
undetectable		 3w9tB-5k21A:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1001_1
(HEMOLYTIC LECTIN
CEL-III)		 5k21 PYOCYANIN
DEMETHYLASE
(Mycolicibacteriu
m
fortuitum) 		4 / 5 ASP A  63
VAL A  64
GLY A  65
ASP A  56
 CA  A 202 (-3.0A)
None
None
CA  A 202 (-3.1A)
 1.25A 3w9tC-5k21A:
undetectable		 3w9tC-5k21A:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD502_1
(HEMOLYTIC LECTIN
CEL-III)		 5k21 PYOCYANIN
DEMETHYLASE
(Mycolicibacteriu
m
fortuitum) 		4 / 5 ASP A  63
VAL A  64
GLY A  65
ASP A  56
 CA  A 202 (-3.0A)
None
None
CA  A 202 (-3.1A)
 1.25A 3w9tD-5k21A:
undetectable		 3w9tD-5k21A:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE504_1
(HEMOLYTIC LECTIN
CEL-III)		 5k21 PYOCYANIN
DEMETHYLASE
(Mycolicibacteriu
m
fortuitum) 		4 / 5 ASP A  63
VAL A  64
GLY A  65
ASP A  56
 CA  A 202 (-3.0A)
None
None
CA  A 202 (-3.1A)
 1.24A 3w9tE-5k21A:
undetectable		 3w9tE-5k21A:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF504_1
(HEMOLYTIC LECTIN
CEL-III)		 5k21 PYOCYANIN
DEMETHYLASE
(Mycolicibacteriu
m
fortuitum) 		4 / 5 ASP A  63
VAL A  64
GLY A  65
ASP A  56
 CA  A 202 (-3.0A)
None
None
CA  A 202 (-3.1A)
 1.25A 3w9tF-5k21A:
undetectable		 3w9tF-5k21A:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG504_1
(HEMOLYTIC LECTIN
CEL-III)		 5k21 PYOCYANIN
DEMETHYLASE
(Mycolicibacteriu
m
fortuitum) 		4 / 5 ASP A  63
VAL A  64
GLY A  65
ASP A  56
 CA  A 202 (-3.0A)
None
None
CA  A 202 (-3.1A)
 1.25A 3w9tG-5k21A:
undetectable		 3w9tG-5k21A:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JVL_A_ESTA702_1
(ESTROGEN
SULFOTRANSFERASE)		 5k21 PYOCYANIN
DEMETHYLASE
(Mycolicibacteriu
m
fortuitum) 		4 / 9 PHE A 126
HIS A 121
PHE A  70
ILE A 106
 6QF  A 201 (-4.4A)
6QF  A 201 (-3.8A)
6QF  A 201 (-3.6A)
None
 1.24A 4jvlA-5k21A:
undetectable		 4jvlA-5k21A:
19.22