SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5k24'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OI8_A_ADNA2_1 (UNCHARACTERIZED PROTEIN)	5k24	METAL TRANSPORTER CNNM3 (Mus musculus)	4 / 6	HIS C 352 PRO C 356 LEU C 440 ASP C 445	None	0.93A	3oi8A-5k24C: 10.0	3oi8A-5k24C: 29.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OI8_B_ADNB1_1 (UNCHARACTERIZED PROTEIN)	5k24	METAL TRANSPORTER CNNM3 (Mus musculus)	5 / 9	HIS C 352 PRO C 356 LEU C 440 GLU C 444 ASP C 445	None	1.04A	3oi8A-5k24C: 10.0 3oi8B-5k24C: 10.1	3oi8A-5k24C: 29.78 3oi8B-5k24C: 29.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OI8_B_ADNB1_1 (UNCHARACTERIZED PROTEIN)	5k24	METAL TRANSPORTER CNNM3 (Mus musculus)	5 / 9	HIS C 352 PRO C 356 THR C 442 GLU C 444 ASP C 445	None	0.85A	3oi8A-5k24C: 10.0 3oi8B-5k24C: 10.1	3oi8A-5k24C: 29.78 3oi8B-5k24C: 29.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FU8_A_ACTA304_0 (UROKINASE-TYPE PLASMINOGEN ACTIVATOR)	5k24	METAL TRANSPORTER CNNM3 (Mus musculus)	3 / 3	ARG C 354 HIS C 418 TYR C 370	None	1.11A	4fu8A-5k24C: undetectable	4fu8A-5k24C: 20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FU9_A_ACTA312_0 (UROKINASE-TYPE PLASMINOGEN ACTIVATOR)	5k24	METAL TRANSPORTER CNNM3 (Mus musculus)	3 / 3	ARG C 354 HIS C 418 TYR C 370	None	1.13A	4fu9A-5k24C: undetectable	4fu9A-5k24C: 20.95

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3OI8_A_ADNA2_1","UNCHARACTERIZED PROTEIN","5k24","METAL TRANSPORTER CNNM3","Mus musculus",4,"HIS C 352;PRO C 356;LEU C 440;ASP C 445","None","0.93A","3oi8A-5k24C:10.0","3oi8A-5k24C:29.78"],["3OI8_B_ADNB1_1","UNCHARACTERIZED PROTEIN;UNCHARACTERIZED PROTEIN","5k24","METAL TRANSPORTER CNNM3","Mus musculus",5,"HIS C 352;PRO C 356;LEU C 440;GLU C 444;ASP C 445","None","1.04A","3oi8A-5k24C:10.0;3oi8B-5k24C:10.1","3oi8A-5k24C:29.78;3oi8B-5k24C:29.78"],["3OI8_B_ADNB1_1","UNCHARACTERIZED PROTEIN;UNCHARACTERIZED PROTEIN","5k24","METAL TRANSPORTER CNNM3","Mus musculus",5,"HIS C 352;PRO C 356;THR C 442;GLU C 444;ASP C 445","None","0.85A","3oi8A-5k24C:10.0;3oi8B-5k24C:10.1","3oi8A-5k24C:29.78;3oi8B-5k24C:29.78"],["4FU8_A_ACTA304_0","UROKINASE-TYPE PLASMINOGEN ACTIVATOR","5k24","METAL TRANSPORTER CNNM3","Mus musculus",3,"ARG C 354;HIS C 418;TYR C 370","None","1.11A","4fu8A-5k24C:undetectable","4fu8A-5k24C:20.95"],["4FU9_A_ACTA312_0","UROKINASE-TYPE PLASMINOGEN ACTIVATOR","5k24","METAL TRANSPORTER CNNM3","Mus musculus",3,"ARG C 354;HIS C 418;TYR C 370","None","1.13A","4fu9A-5k24C:undetectable","4fu9A-5k24C:20.95"]]