SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5k35'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2503_0
(FERROCHELATASE)		 5k35 ANKYRIN-REPEAT
PROTEIN B
(Legionella
pneumophila) 		4 / 4 LEU A  98
PRO A  97
LEU A 113
ARG A 115
 None
 1.43A 1hrkB-5k35A:
undetectable		 1hrkB-5k35A:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA3_B_STRB2001_2
(MINERALOCORTICOID
RECEPTOR)		 5k35 ANKYRIN-REPEAT
PROTEIN B
(Legionella
pneumophila) 		3 / 3 LEU A  99
LEU A 113
MET A 159
 None
 0.74A 1ya3B-5k35A:
undetectable		 1ya3B-5k35A:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1604_0
(FERROCHELATASE)		 5k35 ANKYRIN-REPEAT
PROTEIN B
(Legionella
pneumophila) 		4 / 4 LEU A  98
PRO A  97
LEU A 113
ARG A 115
 None
 1.42A 2hrcB-5k35A:
undetectable		 2hrcB-5k35A:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNJ_B_CHDB503_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5k35 ANKYRIN-REPEAT
PROTEIN B
(Legionella
pneumophila) 		4 / 4 LEU A  98
PRO A  97
LEU A 113
ARG A 115
 None
 1.42A 2pnjB-5k35A:
undetectable		 2pnjB-5k35A:
17.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WEO_A_ACRA1001_2
(ALPHA-GLUCOSIDASE)		 5k35 ANKYRIN-REPEAT
PROTEIN B
(Legionella
pneumophila) 		4 / 6 ILE A 102
ILE A  78
TRP A  60
MET A  64
 None
 1.43A 3weoA-5k35A:
undetectable		 3weoA-5k35A:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNU_A_BEZA319_0
(SHKAI2IB)		 5k35 ANKYRIN-REPEAT
PROTEIN B
(Legionella
pneumophila) 		4 / 5 GLN A 138
ILE A 152
ILE A 156
TYR A 107
 None
 1.21A 5dnuA-5k35A:
undetectable		 5dnuA-5k35A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DNV_A_BEZA304_0
(SHKAI2IB)		 5k35 ANKYRIN-REPEAT
PROTEIN B
(Legionella
pneumophila) 		4 / 5 GLN A 138
ILE A 152
ILE A 156
TYR A 107
 None
 1.16A 5dnvA-5k35A:
undetectable		 5dnvA-5k35A:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA503_1
(ADENOSYLHOMOCYSTEINA
SE)		 5k35 ANKYRIN-REPEAT
PROTEIN B
(Legionella
pneumophila) 		3 / 3 LEU A  72
GLN A 108
LYS A  80
 None
 0.99A 6exiB-5k35A:
undetectable		 6exiB-5k35A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB503_0
(ADENOSYLHOMOCYSTEINA
SE)		 5k35 ANKYRIN-REPEAT
PROTEIN B
(Legionella
pneumophila) 		3 / 3 LEU A  72
GLN A 108
LYS A  80
 None
 0.92A 6exiA-5k35A:
undetectable		 6exiA-5k35A:
19.67