SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5k3j'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_A_FFOA1293_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		3 / 3 SER A  35
GLU A  36
GLU A  37
 None
 0.52A 1eqbD-5k3jA:
undetectable		 1eqbD-5k3jA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EQB_C_FFOC3293_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		3 / 3 SER A  35
GLU A  36
GLU A  37
 None
 0.52A 1eqbB-5k3jA:
undetectable		 1eqbB-5k3jA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3002_1
(SERUM ALBUMIN)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		4 / 8 ASN A 600
LEU A 558
TYR A 350
SER A 607
 None
 1.10A 1hk3A-5k3jA:
undetectable		 1hk3A-5k3jA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHU_A_ESTA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		5 / 12 GLY A 274
MET A 265
LEU A 263
ILE A 206
LEU A 204
 None
 1.24A 1lhuA-5k3jA:
undetectable		 1lhuA-5k3jA:
14.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PW7_B_RABB646_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		5 / 9 ARG A 532
GLY A 397
GLU A 395
GLU A 566
ILE A 400
 None
 1.36A 1pw7B-5k3jA:
undetectable		 1pw7B-5k3jA:
16.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPO_H_TESH1010_1
(ANTI-TESTOSTERONE
(HEAVY CHAIN)
ANTI-TESTOSTERONE
(LIGHT CHAIN))		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		5 / 12 ALA A 305
TYR A 350
GLY A 301
LEU A 302
VAL A  31
 None
 1.12A 1vpoH-5k3jA:
undetectable
1vpoL-5k3jA:
undetectable		 1vpoH-5k3jA:
16.82
1vpoL-5k3jA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XVA_B_ACTB294_0
(GLYCINE
N-METHYLTRANSFERASE)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		4 / 6 ALA A 415
TYR A 314
ILE A 310
LEU A 630
 None
 1.05A 1xvaA-5k3jA:
undetectable
1xvaB-5k3jA:
undetectable		 1xvaA-5k3jA:
18.17
1xvaB-5k3jA:
18.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		5 / 12 ILE A 536
ILE A 535
ALA A 538
ARG A 541
PHE A 352
 None
 1.24A 1xzxX-5k3jA:
undetectable		 1xzxX-5k3jA:
17.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOU_A_CQAA403_0
(HISTAMINE
N-METHYLTRANSFERASE)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		4 / 8 ASP A 557
PHE A 608
ASP A 606
THR A 309
 None
 1.04A 2aouA-5k3jA:
undetectable		 2aouA-5k3jA:
18.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_2
(PROTEASE)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		3 / 3 ARG A 598
VAL A 554
THR A  22
 None
 0.83A 2nmzA-5k3jA:
undetectable		 2nmzA-5k3jA:
10.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA2_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		5 / 12 PHE A 174
LEU A 199
HIS A 214
LEU A 204
TYR A 276
 None
 1.45A 3adsA-5k3jA:
undetectable		 3adsA-5k3jA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		5 / 12 VAL A 420
ILE A 424
ILE A 426
ALA A 307
LEU A 304
 None
 0.96A 3fpjA-5k3jA:
undetectable		 3fpjA-5k3jA:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		3 / 3 ARG A  90
ASP A 115
ASP A  91
 None
 0.88A 3jb2A-5k3jA:
undetectable		 3jb2A-5k3jA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB3_A_SAMA1102_1
(STRUCTURAL PROTEIN
VP3)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		3 / 3 ARG A  90
ASP A 115
ASP A  91
 None
 0.90A 3jb3A-5k3jA:
undetectable		 3jb3A-5k3jA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDI_A_SAMA601_0
(METHYLTRANSFERASE)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		5 / 12 TYR A 350
PHE A 303
ALA A 311
THR A 309
ILE A 610
 None
 1.30A 3ndiA-5k3jA:
undetectable		 3ndiA-5k3jA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_2
(PROTEASE)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		3 / 3 ARG A 598
VAL A 554
THR A  22
 None
 0.82A 3ndtA-5k3jA:
undetectable		 3ndtA-5k3jA:
10.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U52_A_CUA515_0
(PHENOL HYDROXYLASE
COMPONENT PHL
PHENOL HYDROXYLASE
COMPONENT PHN)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		3 / 3 HIS A 100
HIS A 109
ILE A  77
 None
 0.82A 3u52A-5k3jA:
undetectable
3u52C-5k3jA:
undetectable		 3u52A-5k3jA:
20.88
3u52C-5k3jA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZQT_A_30ZA1920_1
(ANDROGEN RECEPTOR)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		4 / 6 PRO A 213
GLY A 212
ASN A 210
ASN A 160
 None
 1.02A 3zqtA-5k3jA:
undetectable		 3zqtA-5k3jA:
17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQF_A_QPSA951_1
(ALPHA-GLUCAN
PHOSPHORYLASE 2,
CYTOSOLIC)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		4 / 6 MET A 298
GLY A 356
ARG A 101
GLU A  94
 None
 1.47A 4bqfA-5k3jA:
undetectable		 4bqfA-5k3jA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU8_A_ACTA304_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		3 / 3 ARG A  42
HIS A  98
TYR A  33
 None
 1.24A 4fu8A-5k3jA:
undetectable		 4fu8A-5k3jA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FU9_A_ACTA312_0
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		3 / 3 ARG A  42
HIS A  98
TYR A  33
 None
 1.30A 4fu9A-5k3jA:
undetectable		 4fu9A-5k3jA:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_B_SFYB806_0
(SEPIAPTERIN
REDUCTASE)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		5 / 11 LEU A  14
SER A 603
LEU A 604
PRO A 599
ALA A 316
 None
 1.42A 4hwkB-5k3jA:
undetectable		 4hwkB-5k3jA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_C_SFYC804_0
(SEPIAPTERIN
REDUCTASE)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		5 / 12 LEU A  14
SER A 603
LEU A 604
PRO A 599
ALA A 316
 None
 1.43A 4hwkC-5k3jA:
undetectable		 4hwkC-5k3jA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HWK_D_SFYD803_0
(SEPIAPTERIN
REDUCTASE)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		5 / 11 LEU A  14
SER A 603
LEU A 604
PRO A 599
ALA A 316
 None
 1.44A 4hwkD-5k3jA:
undetectable		 4hwkD-5k3jA:
17.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KR3_A_GLYA701_0
(GLYCINE--TRNA LIGASE)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		4 / 6 ARG A 598
GLU A  16
ARG A 319
GLU A  13
 None
 1.35A 4kr3A-5k3jA:
undetectable		 4kr3A-5k3jA:
23.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M11_C_MXMC606_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		3 / 3 LEU A  97
ARG A  42
MET A  28
 None
 0.98A 4m11C-5k3jA:
undetectable		 4m11C-5k3jA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAE_A_CLMA207_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		5 / 12 PRO A 120
ALA A 148
ALA A 190
GLY A 189
LEU A 191
 None
None
None
FAD  A 701 (-4.1A)
None
 1.10A 4oaeA-5k3jA:
undetectable		 4oaeA-5k3jA:
15.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OT2_A_NPSA602_1
(SERUM ALBUMIN)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		5 / 6 ARG A 598
ALA A 316
ASP A 334
LEU A  14
SER A 603
 None
 1.19A 4ot2A-5k3jA:
2.6		 4ot2A-5k3jA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QTU_D_SAMD301_1
(PUTATIVE
METHYLTRANSFERASE
BUD23)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		4 / 5 GLN A 614
LEU A 615
SER A 611
ASP A  57
 None
 1.35A 4qtuD-5k3jA:
undetectable		 4qtuD-5k3jA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBS_A_DIFA502_1
(PENTALENIC ACID
SYNTHASE)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		5 / 9 LEU A 304
LEU A 615
THR A 309
LEU A 308
ILE A 310
 None
 1.34A 4ubsA-5k3jA:
0.3		 4ubsA-5k3jA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWJ_D_QELD503_1
(NMDA GLUTAMATE
RECEPTOR SUBUNIT
GLUTAMATE RECEPTOR
IONOTROPIC, NMDA 2B)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		5 / 12 THR A 430
ALA A 393
GLN A 300
ILE A 426
THR A 359
 FAD  A 701 (-4.3A)
None
None
None
None
 1.30A 5ewjC-5k3jA:
undetectable
5ewjD-5k3jA:
undetectable		 5ewjC-5k3jA:
20.51
5ewjD-5k3jA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FA8_A_SAMA301_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE,
PUTATIVE)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		5 / 12 GLY A 108
GLY A 105
ILE A 424
ILE A  77
LEU A  64
 None
 1.17A 5fa8A-5k3jA:
undetectable		 5fa8A-5k3jA:
12.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JSD_B_1GNB603_1
(PHIAB6 TAILSPIKE)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		3 / 3 VAL A 328
GLU A  17
GLU A  16
 None
 0.84A 5jsdB-5k3jA:
undetectable
5jsdC-5k3jA:
undetectable		 5jsdB-5k3jA:
21.58
5jsdC-5k3jA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5K7U_A_SAMA601_1
(N6-ADENOSINE-METHYLT
RANSFERASE 70 KDA
SUBUNIT)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		3 / 3 ASP A 557
ASN A 564
GLN A 589
 None
 0.76A 5k7uA-5k3jA:
undetectable		 5k7uA-5k3jA:
15.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_2
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		4 / 6 PHE A 343
ARG A 348
LEU A 346
ALA A 601
 None
 1.08A 6b89B-5k3jA:
undetectable		 6b89B-5k3jA:
8.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA826_0
(GEPHYRIN)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		3 / 3 HIS A 109
ARG A 141
ILE A  77
 None
 0.81A 6fgdA-5k3jA:
undetectable		 6fgdA-5k3jA:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6R2E_C_FFOC404_0
(THYMIDYLATE SYNTHASE)		 5k3j ACYL-COENZYME A
OXIDASE
(Caenorhabditis
elegans) 		5 / 10 ILE A 536
ASN A 481
LEU A 559
ASN A 564
MET A 540
 None
 1.42A 6r2eC-5k3jA:
undetectable		 6r2eC-5k3jA:
17.92