SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5k5f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PWY_E_AC2E290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5k5f HELICASE-LIKE
TRANSCRIPTION FACTOR
(Homo
sapiens) 		5 / 10 VAL A  83
GLY A 132
MET A 148
ASN A 139
HIS A  66
 None
 1.16A 1pwyE-5k5fA:
undetectable		 1pwyE-5k5fA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V3Q_E_2DIE290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5k5f HELICASE-LIKE
TRANSCRIPTION FACTOR
(Homo
sapiens) 		5 / 10 VAL A  83
GLY A 132
MET A 148
ASN A 139
HIS A  66
 None
 1.22A 1v3qE-5k5fA:
undetectable		 1v3qE-5k5fA:
18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V3Q_E_2DIE290_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5k5f HELICASE-LIKE
TRANSCRIPTION FACTOR
(Homo
sapiens) 		5 / 10 VAL A  83
GLY A 132
MET A 148
VAL A 108
HIS A  66
 None
 1.28A 1v3qE-5k5fA:
undetectable		 1v3qE-5k5fA:
18.22