SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5k5h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MIH_A_CUA358_0
(PEPTIDYL-GLYCINE
ALPHA-AMIDATING
MONOOXYGENASE)		 5k5h TRANSCRIPTIONAL
REPRESSOR CTCF
(Homo
sapiens) 		3 / 3 HIS A 397
HIS A 401
MET A 398
 ZN  A 502 (-3.0A)
ZN  A 502 (-3.1A)
ZN  A 502 ( 4.8A)
 1.01A 3mihA-5k5hA:
undetectable		 3mihA-5k5hA:
16.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_A_CHDA1507_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5k5h TRANSCRIPTIONAL
REPRESSOR CTCF
(Homo
sapiens) 		3 / 3 ARG A 389
LYS A 393
ARG A 368
 None
 1.40A 3w1wA-5k5hA:
undetectable
3w1wB-5k5hA:
undetectable		 3w1wA-5k5hA:
16.51
3w1wB-5k5hA:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB506_0
(FERROCHELATASE,
MITOCHONDRIAL)		 5k5h TRANSCRIPTIONAL
REPRESSOR CTCF
(Homo
sapiens) 		3 / 3 ARG A 368
ARG A 389
LYS A 393
 None
 1.42A 3w1wA-5k5hA:
undetectable
3w1wB-5k5hA:
undetectable		 3w1wA-5k5hA:
16.51
3w1wB-5k5hA:
16.51