SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5k6u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GM7_B_PNNB1577_0
(PENICILLIN G ACYLASE
ALPHA SUBUNIT
PENICILLIN G ACYLASE
BETA SUBUNIT)		 5k6u PROTEIN SIDEKICK-1
(Mus
musculus) 		4 / 8 SER A 244
SER A 137
ALA A 141
ILE A 140
 None
 1.14A 1gm7A-5k6uA:
undetectable
1gm7B-5k6uA:
undetectable		 1gm7A-5k6uA:
18.49
1gm7B-5k6uA:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3003_1
(SERUM ALBUMIN)		 5k6u PROTEIN SIDEKICK-1
(Mus
musculus) 		3 / 4 LYS A 174
ALA A 165
MET A  92
 None
 0.60A 1hk3A-5k6uA:
undetectable		 1hk3A-5k6uA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_B_NCAB901_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 5k6u PROTEIN SIDEKICK-1
(Mus
musculus) 		4 / 5 ILE A 357
PRO A   6
PHE A   8
VAL A  72
 None
 1.48A 2hjhB-5k6uA:
undetectable		 2hjhB-5k6uA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5k6u PROTEIN SIDEKICK-1
(Mus
musculus) 		3 / 3 TYR A 374
GLY A  78
ASP A 325
 None
 0.68A 3ou6C-5k6uA:
undetectable		 3ou6C-5k6uA:
20.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 5k6u PROTEIN SIDEKICK-1
(Mus
musculus) 		5 / 12 ILE A 284
GLY A 367
GLY A 366
ASN A 364
GLY A 314
 None
 1.03A 3vasB-5k6uA:
undetectable		 3vasB-5k6uA:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1476_0
(MJ0495-LIKE PROTEIN)		 5k6u PROTEIN SIDEKICK-1
(Mus
musculus) 		4 / 5 ILE A 308
HIS A 346
MET A 306
ARG A 336
 None
 1.25A 4ac9B-5k6uA:
undetectable
4ac9C-5k6uA:
undetectable		 4ac9B-5k6uA:
23.01
4ac9C-5k6uA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1476_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5k6u PROTEIN SIDEKICK-1
(Mus
musculus) 		4 / 5 ILE A 308
HIS A 346
MET A 306
ARG A 336
 None
 1.25A 4acaB-5k6uA:
undetectable
4acaC-5k6uA:
undetectable		 4acaB-5k6uA:
23.01
4acaC-5k6uA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1476_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5k6u PROTEIN SIDEKICK-1
(Mus
musculus) 		4 / 4 ILE A 308
HIS A 346
MET A 306
ARG A 336
 None
 1.22A 4acbB-5k6uA:
0.0
4acbC-5k6uA:
0.1		 4acbB-5k6uA:
23.01
4acbC-5k6uA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMA_D_ADND604_1
(PYRUVATE KINASE)		 5k6u PROTEIN SIDEKICK-1
(Mus
musculus) 		3 / 3 ARG A 336
GLU A 353
ASN A 334
 None
 0.88A 4imaD-5k6uA:
undetectable		 4imaD-5k6uA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IP7_D_ADND604_1
(PYRUVATE KINASE
ISOZYMES L)		 5k6u PROTEIN SIDEKICK-1
(Mus
musculus) 		3 / 3 ARG A 336
GLU A 353
ASN A 334
 None
 0.88A 4ip7D-5k6uA:
undetectable		 4ip7D-5k6uA:
22.88