SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5k6w'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3003_1
(SERUM ALBUMIN)		 5k6w PROTEIN SIDEKICK-1
(Mus
musculus) 		3 / 4 LYS A 174
ALA A 165
MET A  92
 None
 0.69A 1hk3A-5k6wA:
undetectable		 1hk3A-5k6wA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RLF_A_RIMA199_1
(MATRIX PROTEIN 2)		 5k6w PROTEIN SIDEKICK-1
(Mus
musculus) 		4 / 6 LEU A 440
LEU A 435
ILE A 442
ARG A 441
 None
 1.00A 2rlfA-5k6wA:
undetectable
2rlfB-5k6wA:
undetectable		 2rlfA-5k6wA:
7.57
2rlfB-5k6wA:
7.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_C_SAMC300_1
(SAM-DEPENDENT
METHYLTRANSFERASE)		 5k6w PROTEIN SIDEKICK-1
(Mus
musculus) 		3 / 3 TYR A 374
GLY A  78
ASP A 325
 None
 0.72A 3ou6C-5k6wA:
undetectable		 3ou6C-5k6wA:
19.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_1
(ADENOSINE KINASE,
PUTATIVE)		 5k6w PROTEIN SIDEKICK-1
(Mus
musculus) 		5 / 12 ILE A 284
GLY A 367
GLY A 366
ASN A 364
GLY A 314
 None
 1.04A 3uq6A-5k6wA:
undetectable		 3uq6A-5k6wA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 5k6w PROTEIN SIDEKICK-1
(Mus
musculus) 		5 / 12 ILE A 284
GLY A 367
GLY A 366
ASN A 364
GLY A 314
 None
 1.05A 3vaqA-5k6wA:
undetectable		 3vaqA-5k6wA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 5k6w PROTEIN SIDEKICK-1
(Mus
musculus) 		5 / 12 ILE A 284
GLY A 367
GLY A 366
ASN A 364
GLY A 314
 None
 1.03A 3vasA-5k6wA:
undetectable		 3vasA-5k6wA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 5k6w PROTEIN SIDEKICK-1
(Mus
musculus) 		5 / 12 ILE A 284
GLY A 367
GLY A 366
ASN A 364
GLY A 314
 None
 0.94A 3vasB-5k6wA:
undetectable		 3vasB-5k6wA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1476_0
(MJ0495-LIKE PROTEIN)		 5k6w PROTEIN SIDEKICK-1
(Mus
musculus) 		4 / 5 ILE A 308
HIS A 346
MET A 306
ARG A 336
 None
 1.29A 4ac9B-5k6wA:
undetectable
4ac9C-5k6wA:
undetectable		 4ac9B-5k6wA:
23.33
4ac9C-5k6wA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1476_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5k6w PROTEIN SIDEKICK-1
(Mus
musculus) 		4 / 5 ILE A 308
HIS A 346
MET A 306
ARG A 336
 None
 1.31A 4acaB-5k6wA:
undetectable
4acaC-5k6wA:
undetectable		 4acaB-5k6wA:
23.33
4acaC-5k6wA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1476_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5k6w PROTEIN SIDEKICK-1
(Mus
musculus) 		4 / 4 ILE A 308
HIS A 346
MET A 306
ARG A 336
 None
 1.25A 4acbB-5k6wA:
0.0
4acbC-5k6wA:
0.0		 4acbB-5k6wA:
23.33
4acbC-5k6wA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX7_C_H4BC600_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5k6w PROTEIN SIDEKICK-1
(Mus
musculus) 		4 / 8 ILE A 413
TRP A 415
PHE A 384
GLU A 404
 None
 1.18A 4cx7C-5k6wA:
undetectable
4cx7D-5k6wA:
undetectable		 4cx7C-5k6wA:
21.89
4cx7D-5k6wA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_A_BQ1A1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 5k6w PROTEIN SIDEKICK-1
(Mus
musculus) 		3 / 3 GLU A 368
ALA A 362
PHE A 361
 SO4  A 509 (-3.4A)
None
SO4  A 509 ( 4.1A)
 0.62A 4v1fA-5k6wA:
undetectable		 4v1fA-5k6wA:
10.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_C_BQ1C1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)		 5k6w PROTEIN SIDEKICK-1
(Mus
musculus) 		3 / 3 GLU A 368
ALA A 362
PHE A 361
 SO4  A 509 (-3.4A)
None
SO4  A 509 ( 4.1A)
 0.62A 4v1fC-5k6wA:
undetectable		 4v1fC-5k6wA:
10.92