SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5k6z'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3003_1
(SERUM ALBUMIN)		 5k6z PROTEIN
SIDEKICK-2,PROTEIN
SIDEKICK-1 CHIMERA
(Mus
musculus) 		3 / 4 LYS A 174
ALA A 165
MET A  92
 None
 0.67A 1hk3A-5k6zA:
undetectable		 1hk3A-5k6zA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KQW_A_RTLA135_0
(CELLULAR
RETINOL-BINDING
PROTEIN)		 5k6z PROTEIN
SIDEKICK-2,PROTEIN
SIDEKICK-1 CHIMERA
(Mus
musculus) 		5 / 12 THR A  85
ARG A  45
LEU A  47
LEU A  24
ILE A  58
 None
 1.23A 1kqwA-5k6zA:
undetectable		 1kqwA-5k6zA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y7I_A_SALA502_1
(SALICYLIC
ACID-BINDING PROTEIN
2)		 5k6z PROTEIN
SIDEKICK-2,PROTEIN
SIDEKICK-1 CHIMERA
(Mus
musculus) 		3 / 3 LEU A 340
HIS A 346
LYS A 338
 None
 1.01A 1y7iA-5k6zA:
undetectable		 1y7iA-5k6zA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5k6z PROTEIN
SIDEKICK-2,PROTEIN
SIDEKICK-1 CHIMERA
(Mus
musculus) 		4 / 7 LEU A 299
MET A 306
THR A 305
LEU A 350
 None
 1.11A 2eikA-5k6zA:
undetectable
2eikJ-5k6zA:
undetectable		 2eikA-5k6zA:
21.36
2eikJ-5k6zA:
9.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HJH_B_NCAB901_0
(NAD-DEPENDENT
HISTONE DEACETYLASE
SIR2)		 5k6z PROTEIN
SIDEKICK-2,PROTEIN
SIDEKICK-1 CHIMERA
(Mus
musculus) 		4 / 5 ILE A 179
PRO A 178
PHE A  95
VAL A 163
 None
 1.47A 2hjhB-5k6zA:
undetectable		 2hjhB-5k6zA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_2
(PHOSPHOLIPASE A2)		 5k6z PROTEIN
SIDEKICK-2,PROTEIN
SIDEKICK-1 CHIMERA
(Mus
musculus) 		4 / 5 ILE A 117
SER A 119
PHE A 120
PRO A 121
 None
 1.38A 3bjwC-5k6zA:
undetectable		 3bjwC-5k6zA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_A_RBFA190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 5k6z PROTEIN
SIDEKICK-2,PROTEIN
SIDEKICK-1 CHIMERA
(Mus
musculus) 		5 / 12 LEU A 148
THR A 147
ALA A 110
LEU A 181
LEU A 151
 None
 0.94A 3p5nA-5k6zA:
undetectable		 3p5nA-5k6zA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_B_RBFB190_1
(RIBOFLAVIN UPTAKE
PROTEIN)		 5k6z PROTEIN
SIDEKICK-2,PROTEIN
SIDEKICK-1 CHIMERA
(Mus
musculus) 		5 / 12 LEU A 148
THR A 147
ALA A 110
LEU A 181
LEU A 151
 None
 0.94A 3p5nB-5k6zA:
undetectable		 3p5nB-5k6zA:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 5k6z PROTEIN
SIDEKICK-2,PROTEIN
SIDEKICK-1 CHIMERA
(Mus
musculus) 		5 / 12 ILE A 284
GLY A 367
GLY A 366
ASN A 364
GLY A 314
 None
 0.98A 3vasB-5k6zA:
undetectable		 3vasB-5k6zA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_C_DXCC1476_0
(MJ0495-LIKE PROTEIN)		 5k6z PROTEIN
SIDEKICK-2,PROTEIN
SIDEKICK-1 CHIMERA
(Mus
musculus) 		4 / 5 ILE A 308
HIS A 346
MET A 306
ARG A 336
 None
 1.27A 4ac9B-5k6zA:
undetectable
4ac9C-5k6zA:
undetectable		 4ac9B-5k6zA:
23.33
4ac9C-5k6zA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1476_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5k6z PROTEIN
SIDEKICK-2,PROTEIN
SIDEKICK-1 CHIMERA
(Mus
musculus) 		4 / 5 ILE A 308
HIS A 346
MET A 306
ARG A 336
 None
 1.28A 4acaB-5k6zA:
undetectable
4acaC-5k6zA:
undetectable		 4acaB-5k6zA:
23.33
4acaC-5k6zA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1476_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5k6z PROTEIN
SIDEKICK-2,PROTEIN
SIDEKICK-1 CHIMERA
(Mus
musculus) 		4 / 4 ILE A 308
HIS A 346
MET A 306
ARG A 336
 None
 1.23A 4acbB-5k6zA:
undetectable
4acbC-5k6zA:
undetectable		 4acbB-5k6zA:
23.33
4acbC-5k6zA:
23.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMA_D_ADND604_1
(PYRUVATE KINASE)		 5k6z PROTEIN
SIDEKICK-2,PROTEIN
SIDEKICK-1 CHIMERA
(Mus
musculus) 		3 / 3 ARG A 336
GLU A 353
ASN A 334
 None
 0.82A 4imaD-5k6zA:
undetectable		 4imaD-5k6zA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IP7_D_ADND604_1
(PYRUVATE KINASE
ISOZYMES L)		 5k6z PROTEIN
SIDEKICK-2,PROTEIN
SIDEKICK-1 CHIMERA
(Mus
musculus) 		3 / 3 ARG A 336
GLU A 353
ASN A 334
 None
 0.84A 4ip7D-5k6zA:
undetectable		 4ip7D-5k6zA:
23.78