SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5k70'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK3_A_T44A3003_1
(SERUM ALBUMIN)
5k70 PROTEIN SIDEKICK-2
(Mus
musculus)
3 / 4 LYS A 174
ALA A 165
MET A  92
None
0.84A 1hk3A-5k70A:
undetectable
1hk3A-5k70A:
23.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNI_A_MTKA501_1
(CYTOCHROME P450 2C8)
5k70 PROTEIN SIDEKICK-2
(Mus
musculus)
5 / 12 ASN A 246
ALA A 221
THR A 196
VAL A 273
VAL A 276
None
1.10A 2nniA-5k70A:
undetectable
2nniA-5k70A:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_A_RBFA190_1
(RIBOFLAVIN UPTAKE
PROTEIN)
5k70 PROTEIN SIDEKICK-2
(Mus
musculus)
5 / 12 LEU A 148
THR A 147
ALA A 110
LEU A 181
LEU A 151
None
0.91A 3p5nA-5k70A:
undetectable
3p5nA-5k70A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P5N_B_RBFB190_1
(RIBOFLAVIN UPTAKE
PROTEIN)
5k70 PROTEIN SIDEKICK-2
(Mus
musculus)
5 / 12 LEU A 148
THR A 147
ALA A 110
LEU A 181
LEU A 151
None
0.91A 3p5nB-5k70A:
undetectable
3p5nB-5k70A:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_A_BQ1A1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)
5k70 PROTEIN SIDEKICK-2
(Mus
musculus)
3 / 3 GLU A 368
ALA A 362
PHE A 361
None
0.54A 4v1fA-5k70A:
undetectable
4v1fA-5k70A:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V1F_C_BQ1C1087_0
(F0F1 ATP SYNTHASE
SUBUNIT C)
5k70 PROTEIN SIDEKICK-2
(Mus
musculus)
3 / 3 GLU A 368
ALA A 362
PHE A 361
None
0.56A 4v1fC-5k70A:
undetectable
4v1fC-5k70A:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)
5k70 PROTEIN SIDEKICK-2
(Mus
musculus)
4 / 5 VAL A 111
THR A 147
VAL A 276
LEU A 227
None
0.95A 6bqgA-5k70A:
undetectable
6bqgA-5k70A:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)
5k70 PROTEIN SIDEKICK-2
(Mus
musculus)
3 / 3 ASN A 364
PRO A 288
GLN A 289
None
0.90A 6jnhA-5k70A:
undetectable
6jnhA-5k70A:
17.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA202_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)
5k70 PROTEIN SIDEKICK-2
(Mus
musculus)
3 / 3 ASN A 364
PRO A 288
GLN A 289
None
0.92A 6jogA-5k70A:
undetectable
6jogA-5k70A:
17.49