SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5k79'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 5k79 CYANOVIRIN-N DOMAIN
PROTEIN
(Cyanothece
sp.
PCC
7424) 		3 / 3 TRP A  50
GLU A  40
TYR A 107
 None
PEG  A 201 ( 4.5A)
None
 1.26A 2a3aA-5k79A:
undetectable		 2a3aA-5k79A:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRL_A_DXTA1211_1
(TETRACYCLINE
REPRESSOR PROTEIN
CLASS D)		 5k79 CYANOVIRIN-N DOMAIN
PROTEIN
(Cyanothece
sp.
PCC
7424) 		5 / 12 SER A  34
PHE A  21
THR A  17
LEU A  64
ILE A  11
 None
 1.30A 2xrlA-5k79A:
undetectable		 2xrlA-5k79A:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M5M_A_DX4A401_0
(2-AMINO-4-HYDROXY-6-
HYDROXYMETHYLDIHYDRO
PTERIDINE
PYROPHOSPHOKINASE)		 5k79 CYANOVIRIN-N DOMAIN
PROTEIN
(Cyanothece
sp.
PCC
7424) 		4 / 8 GLY A  46
THR A  58
ASN A  43
ARG A  81
 None
 1.19A 4m5mA-5k79A:
undetectable		 4m5mA-5k79A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 5k79 CYANOVIRIN-N DOMAIN
PROTEIN
(Cyanothece
sp.
PCC
7424) 		3 / 3 THR A  17
SER A  34
ASP A  10
 None
 0.78A 5kvaB-5k79A:
undetectable		 5kvaB-5k79A:
15.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 5k79 CYANOVIRIN-N DOMAIN
PROTEIN
(Cyanothece
sp.
PCC
7424) 		3 / 3 HIS A  97
GLU A  96
TRP A  50
 None
 1.14A 5odqD-5k79A:
undetectable		 5odqD-5k79A:
20.44