SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5k7f'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IWH_A_PEMA501_1
(HEMOGLOBIN ALPHA
CHAIN)		 5k7f TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Myxococcus
xanthus) 		5 / 6 ALA A 129
LYS A 132
LYS A 133
ASP A 136
LEU A  77
 None
 0.97A 1iwhA-5k7fA:
undetectable		 1iwhA-5k7fA:
20.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_B_CAMB2422_0
(CYTOCHROME P450-CAM)		 5k7f TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Myxococcus
xanthus) 		5 / 9 PHE A  72
TYR A 134
VAL A 167
GLY A 165
ILE A 110
 None
 1.38A 2a1oB-5k7fA:
undetectable		 2a1oB-5k7fA:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1435_1
(CHITINASE)		 5k7f TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Myxococcus
xanthus) 		3 / 3 TRP A 105
GLU A  20
TYR A  67
 None
 0.88A 2a3aA-5k7fA:
undetectable		 2a3aA-5k7fA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3B_A_FOLA401_0
(DIHYDROFOLATE
REDUCTASE)		 5k7f TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Myxococcus
xanthus) 		5 / 12 ILE A 112
ARG A  16
THR A  34
ILE A  39
LEU A  60
 None
 1.11A 2w3bA-5k7fA:
undetectable		 2w3bA-5k7fA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AQL_A_TXCA1452_1
(GUANINE DEAMINASE)		 5k7f TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Myxococcus
xanthus) 		5 / 12 LEU A  71
LEU A 100
ARG A 103
GLU A  20
ALA A  23
 None
 1.36A 4aqlA-5k7fA:
undetectable		 4aqlA-5k7fA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A601_1
(SERUM ALBUMIN)		 5k7f TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Myxococcus
xanthus) 		4 / 7 VAL A 158
PRO A 156
LYS A 132
TYR A 134
 None
 0.83A 4lb2A-5k7fA:
2.5		 4lb2A-5k7fA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_A_ACTA603_0
(CHOLINE OXIDASE)		 5k7f TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Myxococcus
xanthus) 		3 / 3 ARG A  79
HIS A  96
SER A  78
 None
 0.52A 4mjwA-5k7fA:
undetectable
4mjwB-5k7fA:
undetectable		 4mjwA-5k7fA:
18.94
4mjwB-5k7fA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MJW_B_ACTB603_0
(CHOLINE OXIDASE)		 5k7f TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Myxococcus
xanthus) 		3 / 3 SER A  78
ARG A  79
HIS A  96
 None
 0.51A 4mjwA-5k7fA:
undetectable
4mjwB-5k7fA:
undetectable		 4mjwA-5k7fA:
18.94
4mjwB-5k7fA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_C_IPHC101_0
(INSULIN)		 5k7f TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Myxococcus
xanthus) 		5 / 11 LEU A  90
LEU A 138
ALA A 141
VAL A  76
LEU A  77
 None
 0.88A 4p65C-5k7fA:
undetectable
4p65D-5k7fA:
undetectable
4p65J-5k7fA:
undetectable
4p65L-5k7fA:
undetectable		 4p65C-5k7fA:
14.00
4p65D-5k7fA:
9.38
4p65J-5k7fA:
9.38
4p65L-5k7fA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_G_IPHG101_0
(INSULIN)		 5k7f TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Myxococcus
xanthus) 		5 / 11 VAL A  76
LEU A  77
LEU A  90
LEU A 138
ALA A 141
 None
 0.84A 4p65B-5k7fA:
undetectable
4p65D-5k7fA:
undetectable
4p65G-5k7fA:
undetectable
4p65H-5k7fA:
undetectable		 4p65B-5k7fA:
9.38
4p65D-5k7fA:
9.38
4p65G-5k7fA:
14.00
4p65H-5k7fA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P65_I_IPHI101_0
(INSULIN)		 5k7f TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Myxococcus
xanthus) 		5 / 12 VAL A  76
LEU A  77
LEU A  90
LEU A 138
ALA A 141
 None
 0.91A 4p65B-5k7fA:
undetectable
4p65D-5k7fA:
undetectable
4p65I-5k7fA:
undetectable
4p65J-5k7fA:
undetectable		 4p65B-5k7fA:
9.38
4p65D-5k7fA:
9.38
4p65I-5k7fA:
14.00
4p65J-5k7fA:
9.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_DIFA601_1
(SERUM ALBUMIN)		 5k7f TRANSCRIPTIONAL
REGULATOR, TETR
FAMILY
(Myxococcus
xanthus) 		5 / 11 LEU A 100
ASN A  97
PHE A 163
LEU A 138
LEU A  77
 None
 1.12A 4zbqA-5k7fA:
undetectable		 4zbqA-5k7fA:
16.64