SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5k94'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1E06_A_IPBA600_0 (ODORANT-BINDING PROTEIN)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	4 / 6	VAL A 8 VAL A 50 ILE A 60 ASN A1267	None	0.96A	1e06A-5k94A: undetectable	1e06A-5k94A: 15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WOP_A_FFOA2888_0 (AMINOMETHYLTRANSFERA SE)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	5 / 10	LEU A1192 LEU A1195 ILE A 161 GLU A 153 LEU A 151	None None None B3P A1401 (-4.0A) None	1.15A	1wopA-5k94A: undetectable	1wopA-5k94A: 21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BFP_D_H4BD1290_1 (PTERIDINE REDUCTASE 1)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	4 / 8	PHE A 85 LEU A 89 LEU A1290 LEU A1284	None	1.02A	2bfpD-5k94A: undetectable	2bfpD-5k94A: 20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2H42_A_VIAA901_1 (CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	5 / 11	ALA A1303 ILE A 108 VAL A 97 LEU A 76 ILE A 79	None	1.21A	2h42A-5k94A: undetectable	2h42A-5k94A: 20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2J2P_E_SC2E1289_1 (FICOLIN-2)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	4 / 6	ASP A1197 THR A1193 LYS A1200 ASP A1358	None	1.28A	2j2pE-5k94A: undetectable 2j2pF-5k94A: undetectable	2j2pE-5k94A: 18.39 2j2pF-5k94A: 18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2PYM_A_1UNA1001_3 (PROTEASE RETROPEPSIN)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	3 / 3	ASP A 120 ASN A 118 THR A1245	None	0.71A	2pymB-5k94A: undetectable	2pymB-5k94A: 13.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VE3_A_REAA1445_1 (PUTATIVE CYTOCHROME P450 120)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	5 / 12	ALA A1264 LEU A1280 PHE A1279 VAL A1293 GLY A 16	None	1.11A	2ve3A-5k94A: undetectable	2ve3A-5k94A: 21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VE3_B_REAB1445_1 (PUTATIVE CYTOCHROME P450 120)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	5 / 12	TRP A1230 ALA A1231 THR A1320 GLY A1260 PRO A1257	B3P A1401 (-3.3A) None None None None	1.19A	2ve3B-5k94A: undetectable	2ve3B-5k94A: 21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YGN_A_ACTA1181_0 (WNT INHIBITORY FACTOR 1)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	3 / 3	TYR A 326 VAL A 357 THR A 321	None	0.83A	2ygnA-5k94A: undetectable	2ygnA-5k94A: 15.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A35_A_RBFA191_1 (LUMAZINE PROTEIN)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	5 / 12	LEU A1192 THR A1193 ALA A1346 THR A1345 ILE A1348	None	1.22A	3a35A-5k94A: undetectable	3a35A-5k94A: 16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3A51_C_VDYC6178_1 (VITAMIN D HYDROXYLASE)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	5 / 12	ILE A 108 LEU A1262 ILE A 59 VAL A 23 LEU A 20	None	1.03A	3a51C-5k94A: undetectable	3a51C-5k94A: 21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_E_TRPE1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	4 / 7	GLY A 352 HIS A 308 ASP A1177 ILE A1178	None	0.85A	3fi0E-5k94A: undetectable	3fi0E-5k94A: 22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3FI0_P_TRPP1001_0 (TRYPTOPHANYL-TRNA SYNTHETASE)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	4 / 7	GLY A 352 HIS A 308 ASP A1177 ILE A1178	None	0.82A	3fi0P-5k94A: undetectable	3fi0P-5k94A: 22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GV1_B_BEZB301_0 (DISULFIDE INTERCHANGE PROTEIN)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	4 / 6	LEU A 147 ALA A1223 PRO A 125 PRO A 126	None	1.34A	3gv1A-5k94A: undetectable 3gv1B-5k94A: undetectable	3gv1A-5k94A: 12.40 3gv1B-5k94A: 12.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3HS6_A_EPAA1_1 (PROSTAGLANDIN G/H SYNTHASE 2)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	5 / 12	VAL A1343 GLY A1187 ALA A1188 LEU A1192 LEU A 160	None	1.02A	3hs6A-5k94A: undetectable	3hs6A-5k94A: 23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JUS_A_ECLA600_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	4 / 8	LEU A 306 GLY A 352 ALA A 356 ILE A 243	None	0.70A	3jusA-5k94A: undetectable	3jusA-5k94A: 21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JUS_A_ECNA602_1 (LANOSTEROL 14-ALPHA DEMETHYLASE)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	4 / 8	LEU A 306 GLY A 352 ALA A 356 ILE A 243	None	0.70A	3jusA-5k94A: undetectable	3jusA-5k94A: 21.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3JYR_A_ACRA371_2 (MALTOSE-BINDING PERIPLASMIC PROTEIN)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	4 / 7	GLU A 153 TYR A 155 MET A1330 TRP A1340	B3P A1401 (-4.0A) B3P A1401 ( 4.1A) None None	0.49A	3jyrA-5k94A: 45.5	3jyrA-5k94A: 66.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3N8Y_B_DIFB585_1 (PROSTAGLANDIN G/H SYNTHASE 1)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	5 / 12	VAL A1196 LEU A 160 GLY A1187 ALA A1188 LEU A1361	None	0.97A	3n8yB-5k94A: undetectable	3n8yB-5k94A: 22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OCT_A_1N1A663_2 (TYROSINE-PROTEIN KINASE BTK)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	4 / 5	ILE A1178 MET A 305 ASN A 303 PHE A 169	None	1.37A	3octA-5k94A: undetectable	3octA-5k94A: 19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UFN_A_ROCA401_1 (HIV-1 PROTEASE)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	5 / 11	GLY A1300 ALA A1301 VAL A1259 GLY A1260 THR A 93	None	0.86A	3ufnA-5k94A: undetectable	3ufnA-5k94A: 12.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3VFJ_A_ACTA410_0 (MALTOSE-BINDING PERIPLASMIC PROTEIN, C-TERMINAL FUSED BY CYS-LYS-D-ALA-D-ALA)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	4 / 4	LYS A 15 ALA A 63 GLU A 111 LEU A1262	None	0.76A	3vfjA-5k94A: 50.0	3vfjA-5k94A: 71.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VYW_D_SAMD401_1 (MNMC2)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	4 / 5	GLU A1308 ASP A1314 ASP A1287 ASN A1294	None	1.40A	3vywD-5k94A: undetectable	3vywD-5k94A: 22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W9T_A_W9TA1001_1 (HEMOLYTIC LECTIN CEL-III)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	4 / 5	VAL A 23 GLY A 24 TYR A1283 ASP A 30	None	1.32A	3w9tA-5k94A: undetectable	3w9tA-5k94A: 22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W9T_B_W9TB503_1 (HEMOLYTIC LECTIN CEL-III)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	4 / 5	VAL A 23 GLY A 24 TYR A1283 ASP A 30	None	1.31A	3w9tB-5k94A: undetectable	3w9tB-5k94A: 22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W9T_C_W9TC1001_1 (HEMOLYTIC LECTIN CEL-III)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	4 / 5	VAL A 23 GLY A 24 TYR A1283 ASP A 30	None	1.32A	3w9tC-5k94A: undetectable	3w9tC-5k94A: 22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W9T_D_W9TD502_1 (HEMOLYTIC LECTIN CEL-III)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	4 / 5	VAL A 23 GLY A 24 TYR A1283 ASP A 30	None	1.31A	3w9tD-5k94A: undetectable	3w9tD-5k94A: 22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W9T_E_W9TE504_1 (HEMOLYTIC LECTIN CEL-III)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	4 / 5	VAL A 23 GLY A 24 TYR A1283 ASP A 30	None	1.32A	3w9tE-5k94A: undetectable	3w9tE-5k94A: 22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W9T_G_W9TG504_1 (HEMOLYTIC LECTIN CEL-III)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	4 / 5	VAL A 23 GLY A 24 TYR A1283 ASP A 30	None	1.31A	3w9tG-5k94A: undetectable	3w9tG-5k94A: 22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4A97_I_ZPCI1318_2 (CYS-LOOP LIGAND-GATED ION CHANNEL)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	4 / 6	GLU A 358 ILE A 365 HIS A 308 VAL A 272	None	1.20A	4a97I-5k94A: undetectable	4a97I-5k94A: 21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CX7_D_H4BD600_1 (NITRIC OXIDE SYNTHASE, INDUCIBLE)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	4 / 7	PHE A 320 GLU A 358 ARG A 315 ILE A 335	None	1.34A	4cx7C-5k94A: undetectable 4cx7D-5k94A: undetectable	4cx7C-5k94A: 21.21 4cx7D-5k94A: 21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4F84_A_SAMA501_0 (GERANYL DIPHOSPHATE 2-C-METHYLTRANSFERAS E)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	5 / 12	GLY A 278 GLY A 261 THR A 275 GLN A 249 VAL A 310	None	1.19A	4f84A-5k94A: undetectable	4f84A-5k94A: 23.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4N48_A_SAMA601_1 (CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-M ETHYLTRANSFERASE 1)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	4 / 5	ASN A1267 ALA A 51 GLY A 56 ASP A 14	None	0.97A	4n48A-5k94A: undetectable	4n48A-5k94A: 21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WNW_B_RTZB602_2 (CYTOCHROME P450 2D6)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	3 / 3	GLU A 368 ILE A 335 ALA A 356	None	0.53A	4wnwB-5k94A: undetectable	4wnwB-5k94A: 20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5W4Z_A_RBFA502_1 (RIBOFLAVIN LYASE)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	6 / 12	ALA A1342 ALA A1338 GLY A 166 ALA A1188 PHE A 169 VAL A1181	None	1.39A	5w4zA-5k94A: undetectable	5w4zA-5k94A: 8.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5W4Z_B_RBFB502_1 (RIBOFLAVIN LYASE)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	6 / 12	ALA A1342 ALA A1338 GLY A 166 ALA A1188 PHE A 169 VAL A1181	None	1.41A	5w4zB-5k94A: undetectable	5w4zB-5k94A: 8.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5XDH_B_DAHB60_1 (PUTATIVE CYTOCHROME C)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	4 / 5	MET A 305 ASN A 240 VAL A 310 LEU A 306	None	1.36A	5xdhB-5k94A: undetectable	5xdhB-5k94A: 11.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6B58_A_ACTA603_0 (FUMARATE REDUCTASE FLAVOPROTEIN SUBUNIT)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	3 / 3	TYR A 155 ASN A1227 LEU A 113	B3P A1401 ( 4.1A) None None	0.79A	6b58A-5k94A: undetectable	6b58A-5k94A: 22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6BM5_A_SAMA1301_0 (METHIONINE SYNTHASE)	5k94	MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN (Escherichia coli)	5 / 11	PRO A 133 GLU A 130 PRO A1254 ALA A 163 PRO A 159	None	1.43A	6bm5A-5k94A: undetectable	6bm5A-5k94A: 22.90

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1E06_A_IPBA600_0","ODORANT-BINDING PROTEIN","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",4,"VAL A   8;VAL A  50;ILE A  60;ASN A1267","None","0.96A","1e06A-5k94A:undetectable","1e06A-5k94A:15.94"],["1WOP_A_FFOA2888_0","AMINOMETHYLTRANSFERASE","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",5,"LEU A1192;LEU A1195;ILE A 161;GLU A 153;LEU A 151","None;None;None;B3P A1401 (-4.0A);None","1.15A","1wopA-5k94A:undetectable","1wopA-5k94A:21.52"],["2BFP_D_H4BD1290_1","PTERIDINE REDUCTASE 1","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",4,"PHE A  85;LEU A  89;LEU A1290;LEU A1284","None","1.02A","2bfpD-5k94A:undetectable","2bfpD-5k94A:20.24"],["2H42_A_VIAA901_1","CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",5,"ALA A1303;ILE A 108;VAL A  97;LEU A  76;ILE A  79","None","1.21A","2h42A-5k94A:undetectable","2h42A-5k94A:20.90"],["2J2P_E_SC2E1289_1","FICOLIN-2;FICOLIN-2","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",4,"ASP A1197;THR A1193;LYS A1200;ASP A1358","None","1.28A","2j2pE-5k94A:undetectable;2j2pF-5k94A:undetectable","2j2pE-5k94A:18.39;2j2pF-5k94A:18.39"],["2PYM_A_1UNA1001_3","PROTEASE RETROPEPSIN;PROTEASE RETROPEPSIN","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",3,"ASP A 120;ASN A 118;THR A1245","None","0.71A","2pymB-5k94A:undetectable","2pymB-5k94A:13.08"],["2VE3_A_REAA1445_1","PUTATIVE CYTOCHROME P450 120","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",5,"ALA A1264;LEU A1280;PHE A1279;VAL A1293;GLY A  16","None","1.11A","2ve3A-5k94A:undetectable","2ve3A-5k94A:21.83"],["2VE3_B_REAB1445_1","PUTATIVE CYTOCHROME P450 120","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",5,"TRP A1230;ALA A1231;THR A1320;GLY A1260;PRO A1257","B3P A1401 (-3.3A);None;None;None;None","1.19A","2ve3B-5k94A:undetectable","2ve3B-5k94A:21.83"],["2YGN_A_ACTA1181_0","WNT INHIBITORY FACTOR 1","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",3,"TYR A 326;VAL A 357;THR A 321","None","0.83A","2ygnA-5k94A:undetectable","2ygnA-5k94A:15.48"],["3A35_A_RBFA191_1","LUMAZINE PROTEIN","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",5,"LEU A1192;THR A1193;ALA A1346;THR A1345;ILE A1348","None","1.22A","3a35A-5k94A:undetectable","3a35A-5k94A:16.01"],["3A51_C_VDYC6178_1","VITAMIN D HYDROXYLASE","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",5,"ILE A 108;LEU A1262;ILE A  59;VAL A  23;LEU A  20","None","1.03A","3a51C-5k94A:undetectable","3a51C-5k94A:21.02"],["3FI0_E_TRPE1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",4,"GLY A 352;HIS A 308;ASP A1177;ILE A1178","None","0.85A","3fi0E-5k94A:undetectable","3fi0E-5k94A:22.04"],["3FI0_P_TRPP1001_0","TRYPTOPHANYL-TRNA SYNTHETASE","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",4,"GLY A 352;HIS A 308;ASP A1177;ILE A1178","None","0.82A","3fi0P-5k94A:undetectable","3fi0P-5k94A:22.04"],["3GV1_B_BEZB301_0","DISULFIDE INTERCHANGE PROTEIN","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",4,"LEU A 147;ALA A1223;PRO A 125;PRO A 126","None","1.34A","3gv1A-5k94A:undetectable;3gv1B-5k94A:undetectable","3gv1A-5k94A:12.40;3gv1B-5k94A:12.40"],["3HS6_A_EPAA1_1","PROSTAGLANDIN G\/H SYNTHASE 2","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",5,"VAL A1343;GLY A1187;ALA A1188;LEU A1192;LEU A 160","None","1.02A","3hs6A-5k94A:undetectable","3hs6A-5k94A:23.10"],["3JUS_A_ECLA600_1","LANOSTEROL 14-ALPHA DEMETHYLASE","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",4,"LEU A 306;GLY A 352;ALA A 356;ILE A 243","None","0.70A","3jusA-5k94A:undetectable","3jusA-5k94A:21.85"],["3JUS_A_ECNA602_1","LANOSTEROL 14-ALPHA DEMETHYLASE","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",4,"LEU A 306;GLY A 352;ALA A 356;ILE A 243","None","0.70A","3jusA-5k94A:undetectable","3jusA-5k94A:21.85"],["3JYR_A_ACRA371_2","MALTOSE-BINDING PERIPLASMIC PROTEIN","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",4,"GLU A 153;TYR A 155;MET A1330;TRP A1340","B3P A1401 (-4.0A);B3P A1401 ( 4.1A);None;None","0.49A","3jyrA-5k94A:45.5","3jyrA-5k94A:66.60"],["3N8Y_B_DIFB585_1","PROSTAGLANDIN G\/H SYNTHASE 1","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",5,"VAL A1196;LEU A 160;GLY A1187;ALA A1188;LEU A1361","None","0.97A","3n8yB-5k94A:undetectable","3n8yB-5k94A:22.54"],["3OCT_A_1N1A663_2","TYROSINE-PROTEIN KINASE BTK","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",4,"ILE A1178;MET A 305;ASN A 303;PHE A 169","None","1.37A","3octA-5k94A:undetectable","3octA-5k94A:19.53"],["3UFN_A_ROCA401_1","HIV-1 PROTEASE","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",5,"GLY A1300;ALA A1301;VAL A1259;GLY A1260;THR A  93","None","0.86A","3ufnA-5k94A:undetectable","3ufnA-5k94A:12.42"],["3VFJ_A_ACTA410_0","MALTOSE-BINDING PERIPLASMIC PROTEIN, C-TERMINAL FUSED BY CYS-LYS-D-ALA-D-ALA","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",4,"LYS A  15;ALA A  63;GLU A 111;LEU A1262","None","0.76A","3vfjA-5k94A:50.0","3vfjA-5k94A:71.35"],["3VYW_D_SAMD401_1","MNMC2","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",4,"GLU A1308;ASP A1314;ASP A1287;ASN A1294","None","1.40A","3vywD-5k94A:undetectable","3vywD-5k94A:22.24"],["3W9T_A_W9TA1001_1","HEMOLYTIC LECTIN CEL-III","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",4,"VAL A  23;GLY A  24;TYR A1283;ASP A  30","None","1.32A","3w9tA-5k94A:undetectable","3w9tA-5k94A:22.56"],["3W9T_B_W9TB503_1","HEMOLYTIC LECTIN CEL-III","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",4,"VAL A  23;GLY A  24;TYR A1283;ASP A  30","None","1.31A","3w9tB-5k94A:undetectable","3w9tB-5k94A:22.56"],["3W9T_C_W9TC1001_1","HEMOLYTIC LECTIN CEL-III","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",4,"VAL A  23;GLY A  24;TYR A1283;ASP A  30","None","1.32A","3w9tC-5k94A:undetectable","3w9tC-5k94A:22.56"],["3W9T_D_W9TD502_1","HEMOLYTIC LECTIN CEL-III","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",4,"VAL A  23;GLY A  24;TYR A1283;ASP A  30","None","1.31A","3w9tD-5k94A:undetectable","3w9tD-5k94A:22.56"],["3W9T_E_W9TE504_1","HEMOLYTIC LECTIN CEL-III","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",4,"VAL A  23;GLY A  24;TYR A1283;ASP A  30","None","1.32A","3w9tE-5k94A:undetectable","3w9tE-5k94A:22.56"],["3W9T_G_W9TG504_1","HEMOLYTIC LECTIN CEL-III","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",4,"VAL A  23;GLY A  24;TYR A1283;ASP A  30","None","1.31A","3w9tG-5k94A:undetectable","3w9tG-5k94A:22.56"],["4A97_I_ZPCI1318_2","CYS-LOOP LIGAND-GATED ION CHANNEL","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",4,"GLU A 358;ILE A 365;HIS A 308;VAL A 272","None","1.20A","4a97I-5k94A:undetectable","4a97I-5k94A:21.25"],["4CX7_D_H4BD600_1","NITRIC OXIDE SYNTHASE, INDUCIBLE;NITRIC OXIDE SYNTHASE, INDUCIBLE","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",4,"PHE A 320;GLU A 358;ARG A 315;ILE A 335","None","1.34A","4cx7C-5k94A:undetectable;4cx7D-5k94A:undetectable","4cx7C-5k94A:21.21;4cx7D-5k94A:21.21"],["4F84_A_SAMA501_0","GERANYL DIPHOSPHATE 2-C-METHYLTRANSFERASE","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",5,"GLY A 278;GLY A 261;THR A 275;GLN A 249;VAL A 310","None","1.19A","4f84A-5k94A:undetectable","4f84A-5k94A:23.45"],["4N48_A_SAMA601_1","CAP-SPECIFIC MRNA (NUCLEOSIDE-2'-O-)-METHYLTRANSFERASE 1","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",4,"ASN A1267;ALA A  51;GLY A  56;ASP A  14","None","0.97A","4n48A-5k94A:undetectable","4n48A-5k94A:21.22"],["4WNW_B_RTZB602_2","CYTOCHROME P450 2D6","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",3,"GLU A 368;ILE A 335;ALA A 356","None","0.53A","4wnwB-5k94A:undetectable","4wnwB-5k94A:20.97"],["5W4Z_A_RBFA502_1","RIBOFLAVIN LYASE","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",6,"ALA A1342;ALA A1338;GLY A 166;ALA A1188;PHE A 169;VAL A1181","None","1.39A","5w4zA-5k94A:undetectable","5w4zA-5k94A:8.87"],["5W4Z_B_RBFB502_1","RIBOFLAVIN LYASE","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",6,"ALA A1342;ALA A1338;GLY A 166;ALA A1188;PHE A 169;VAL A1181","None","1.41A","5w4zB-5k94A:undetectable","5w4zB-5k94A:8.87"],["5XDH_B_DAHB60_1","PUTATIVE CYTOCHROME C","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",4,"MET A 305;ASN A 240;VAL A 310;LEU A 306","None","1.36A","5xdhB-5k94A:undetectable","5xdhB-5k94A:11.31"],["6B58_A_ACTA603_0","FUMARATE REDUCTASE FLAVOPROTEIN SUBUNIT","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",3,"TYR A 155;ASN A1227;LEU A 113","B3P A1401 ( 4.1A);None;None","0.79A","6b58A-5k94A:undetectable","6b58A-5k94A:22.40"],["6BM5_A_SAMA1301_0","METHIONINE SYNTHASE","5k94","MALTOSE-BINDING PERIPLASMIC PROTEIN,PROTEIN TRANSLOCASE SUBUNIT SECA,MALTOSE-BINDING PERIPLASMIC PROTEIN","Escherichia coli",5,"PRO A 133;GLU A 130;PRO A1254;ALA A 163;PRO A 159","None","1.43A","6bm5A-5k94A:undetectable","6bm5A-5k94A:22.90"]]