SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5k97'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_D_IMND476_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 5k97 FLAP ENDONUCLEASE 1
(Homo
sapiens) 		5 / 12 THR A  71
ILE A  79
VAL A  31
TYR A  83
ILE A 150
 None
 1.00A 1z9hD-5k97A:
undetectable		 1z9hD-5k97A:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2KCE_A_D16A566_1
(THYMIDYLATE SYNTHASE)		 5k97 FLAP ENDONUCLEASE 1
(Homo
sapiens) 		5 / 12 SER A 331
GLY A  28
TYR A 173
VAL A  31
ALA A 174
 None
 1.32A 2kceA-5k97A:
undetectable		 2kceA-5k97A:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA804_1
(CATALASE-PEROXIDASE)		 5k97 FLAP ENDONUCLEASE 1
(Homo
sapiens) 		3 / 3 ASN A  21
GLU A 206
ARG A  19
 None
 0.82A 3wxoA-5k97A:
0.3		 3wxoA-5k97A:
18.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 5k97 FLAP ENDONUCLEASE 1
(Homo
sapiens) 		5 / 10 LEU A 226
LEU A 209
ILE A 212
LEU A 213
LEU A   9
 None
 0.92A 4odoA-5k97A:
undetectable		 4odoA-5k97A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_B_FK5B203_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 5k97 FLAP ENDONUCLEASE 1
(Homo
sapiens) 		5 / 10 LEU A 226
LEU A 209
ILE A 212
LEU A 213
LEU A   9
 None
 0.95A 4odoB-5k97A:
undetectable		 4odoB-5k97A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_C_FK5C204_1
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 5k97 FLAP ENDONUCLEASE 1
(Homo
sapiens) 		5 / 10 LEU A 226
LEU A 209
ILE A 212
LEU A 213
LEU A   9
 None
 0.95A 4odoC-5k97A:
undetectable		 4odoC-5k97A:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR1_B_017B101_1
(PROTEASE PR5-DRV)		 5k97 FLAP ENDONUCLEASE 1
(Homo
sapiens) 		5 / 10 ALA A 246
ASP A 248
GLY A 240
VAL A 260
ILE A 259
 None
 1.04A 5kr1A-5k97A:
undetectable		 5kr1A-5k97A:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5PHH_A_LDPA414_1
(LYSINE-SPECIFIC
DEMETHYLASE 4D)		 5k97 FLAP ENDONUCLEASE 1
(Homo
sapiens) 		4 / 6 GLU A  96
ARG A 103
ALA A  98
LEU A  97
 None
 1.03A 5phhA-5k97A:
undetectable		 5phhA-5k97A:
21.61