SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5k9h'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 5k9h 0940_GH29
(unidentified) 		4 / 6 ASN A 175
ALA A 174
GLY A 172
TYR A 171
 None
 0.91A 1c8lA-5k9hA:
undetectable		 1c8lA-5k9hA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 5k9h 0940_GH29
(unidentified) 		4 / 6 ASN A 175
ALA A 174
GLY A 172
TYR A 171
 None
 0.89A 1gfzA-5k9hA:
undetectable		 1gfzA-5k9hA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_D_DVAD8_0
(GRAMICIDIN A)		 5k9h 0940_GH29
(unidentified) 		3 / 3 TRP A  17
VAL A 159
TRP A 205
 None
 1.27A 1gmkC-5k9hA:
undetectable
1gmkD-5k9hA:
undetectable		 1gmkC-5k9hA:
1.79
1gmkD-5k9hA:
1.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5k9h 0940_GH29
(unidentified) 		4 / 6 ASN A 175
ALA A 174
GLY A 172
TYR A 171
 None
 0.89A 1l5qA-5k9hA:
undetectable		 1l5qA-5k9hA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L5Q_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5k9h 0940_GH29
(unidentified) 		4 / 6 ASN A 175
ALA A 174
GLY A 172
TYR A 171
 None
 0.90A 1l5qB-5k9hA:
undetectable		 1l5qB-5k9hA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_A_CFFA863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5k9h 0940_GH29
(unidentified) 		4 / 6 ASN A 175
ALA A 174
GLY A 172
TYR A 171
 None
 0.93A 1l7xA-5k9hA:
undetectable		 1l7xA-5k9hA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1L7X_B_CFFB1863_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5k9h 0940_GH29
(unidentified) 		4 / 6 ASN A 175
ALA A 174
GLY A 172
TYR A 171
 None
 0.91A 1l7xB-5k9hA:
undetectable		 1l7xB-5k9hA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_B_DMEB996_1
(ACETYLCHOLINESTERASE)		 5k9h 0940_GH29
(unidentified) 		4 / 6 TRP A 205
GLU A 220
TYR A  23
GLY A  69
 None
GOL  A 602 ( 3.1A)
None
None
 1.13A 1maaB-5k9hA:
undetectable
1maaD-5k9hA:
undetectable		 1maaB-5k9hA:
22.51
1maaD-5k9hA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG1_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 5k9h 0940_GH29
(unidentified) 		3 / 3 TRP A 253
VAL A 254
PRO A 255
 None
SCN  A 621 ( 4.9A)
None
 0.27A 1rg1A-5k9hA:
undetectable		 1rg1A-5k9hA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RH0_A_SPMA999_1
(TYROSYL-DNA
PHOSPHODIESTERASE 1)		 5k9h 0940_GH29
(unidentified) 		3 / 3 TRP A 253
VAL A 254
PRO A 255
 None
SCN  A 621 ( 4.9A)
None
 0.28A 1rh0A-5k9hA:
undetectable		 1rh0A-5k9hA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UHO_A_VDNA1000_1
(CGMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE)		 5k9h 0940_GH29
(unidentified) 		5 / 10 TYR A 287
ALA A 446
LEU A 439
MET A 322
PHE A 319
 None
 1.24A 1uhoA-5k9hA:
undetectable		 1uhoA-5k9hA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_A_SHHA2452_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5k9h 0940_GH29
(unidentified) 		5 / 11 LEU A 146
PHE A 161
ASP A 213
GLY A 212
TYR A 192
 None
None
NA  A 629 ( 4.9A)
NA  A 629 (-4.5A)
None
 1.07A 1zz1A-5k9hA:
undetectable		 1zz1A-5k9hA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZ1_B_SHHB2552_1
(HISTONE
DEACETYLASE-LIKE
AMIDOHYDROLASE)		 5k9h 0940_GH29
(unidentified) 		5 / 12 LEU A 146
PHE A 161
ASP A 213
GLY A 212
TYR A 192
 None
None
NA  A 629 ( 4.9A)
NA  A 629 (-4.5A)
None
 1.07A 1zz1B-5k9hA:
undetectable
1zz1C-5k9hA:
undetectable		 1zz1B-5k9hA:
19.97
1zz1C-5k9hA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BCR_A_AZZA940_1
(GLYCOGEN
PHOSPHORYLASE,
MUSCLE FORM)		 5k9h 0940_GH29
(unidentified) 		4 / 5 ASN A 175
ALA A 174
GLY A 172
TYR A 171
 None
 0.90A 3bcrA-5k9hA:
undetectable		 3bcrA-5k9hA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_1
(N,N-DIMETHYLTRANSFER
ASE)		 5k9h 0940_GH29
(unidentified) 		3 / 3 TYR A 286
GLU A 360
ASP A 362
 SCN  A 624 ( 4.7A)
None
None
 0.87A 3bxoB-5k9hA:
undetectable		 3bxoB-5k9hA:
14.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5k9h 0940_GH29
(unidentified) 		4 / 6 ASN A 175
ALA A 174
GLY A 172
TYR A 171
 None
 0.89A 3dd1A-5k9hA:
undetectable		 3dd1A-5k9hA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DD1_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5k9h 0940_GH29
(unidentified) 		4 / 6 ASN A 175
ALA A 174
GLY A 172
TYR A 171
 None
 0.90A 3dd1B-5k9hA:
undetectable		 3dd1B-5k9hA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_A_CFFA904_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5k9h 0940_GH29
(unidentified) 		4 / 6 ASN A 175
ALA A 174
GLY A 172
TYR A 171
 None
 0.89A 3ddsA-5k9hA:
undetectable		 3ddsA-5k9hA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDS_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5k9h 0940_GH29
(unidentified) 		4 / 6 ASN A 175
ALA A 174
GLY A 172
TYR A 171
 None
 0.90A 3ddsB-5k9hA:
undetectable		 3ddsB-5k9hA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_A_CFFA903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5k9h 0940_GH29
(unidentified) 		4 / 6 ASN A 175
ALA A 174
GLY A 172
TYR A 171
 None
 0.90A 3ddwA-5k9hA:
undetectable		 3ddwA-5k9hA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDW_B_CFFB903_1
(GLYCOGEN
PHOSPHORYLASE, LIVER
FORM)		 5k9h 0940_GH29
(unidentified) 		4 / 6 ASN A 175
ALA A 174
GLY A 172
TYR A 171
 None
 0.91A 3ddwB-5k9hA:
undetectable		 3ddwB-5k9hA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU9_B_SPMB700_1
(POLYAMINE OXIDASE)		 5k9h 0940_GH29
(unidentified) 		4 / 7 GLU A 257
GLU A 158
PHE A  25
TYR A  23
 None
 1.26A 3ku9B-5k9hA:
undetectable		 3ku9B-5k9hA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5J_A_08HA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5k9h 0940_GH29
(unidentified) 		4 / 7 TRP A 188
LEU A 146
LEU A 150
ILE A 204
 None
 0.85A 3u5jA-5k9hA:
undetectable		 3u5jA-5k9hA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_A_08JA1_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5k9h 0940_GH29
(unidentified) 		4 / 8 TRP A 188
LEU A 146
LEU A 150
ILE A 204
 None
 0.87A 3u5kA-5k9hA:
undetectable		 3u5kA-5k9hA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U5K_C_08JC3_1
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5k9h 0940_GH29
(unidentified) 		4 / 8 TRP A 188
LEU A 146
LEU A 150
ILE A 204
 None
 0.92A 3u5kC-5k9hA:
undetectable		 3u5kC-5k9hA:
9.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_A_ADNA2414_1
(RNA-DIRECTED RNA
POLYMERASE L)		 5k9h 0940_GH29
(unidentified) 		4 / 6 GLU A  37
ARG A 263
TYR A 268
HIS A 269
 None
 1.37A 4uciA-5k9hA:
undetectable		 4uciA-5k9hA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCI_B_ADNB2415_1
(RNA-DIRECTED RNA
POLYMERASE L)		 5k9h 0940_GH29
(unidentified) 		4 / 7 GLU A  37
ARG A 263
TYR A 268
HIS A 269
 None
 1.34A 4uciB-5k9hA:
undetectable		 4uciB-5k9hA:
21.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WH5_A_3QBA204_1
(LINCOSAMIDE
RESISTANCE PROTEIN)		 5k9h 0940_GH29
(unidentified) 		5 / 12 GLY A 395
ASP A 394
PHE A 417
PHE A 357
ILE A 405
 None
 1.38A 4wh5A-5k9hA:
undetectable		 4wh5A-5k9hA:
14.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPW_B_3CJB609_1
(LACTOPEROXIDASE)		 5k9h 0940_GH29
(unidentified) 		4 / 4 GLN A  18
HIS A 401
ARG A 402
ARG A  68
 None
None
GOL  A 606 (-3.3A)
SCN  A 624 ( 3.6A)
 1.26A 5hpwB-5k9hA:
0.0		 5hpwB-5k9hA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_A_Z80A401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 5k9h 0940_GH29
(unidentified) 		5 / 11 ILE A 302
ILE A 308
PHE A 300
ILE A  70
ALA A  24
 None
 0.94A 5lg3A-5k9hA:
undetectable		 5lg3A-5k9hA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LG3_E_Z80E401_1
(GAMMA-AMINOBUTYRIC-A
CID RECEPTOR SUBUNIT
BETA-1)		 5k9h 0940_GH29
(unidentified) 		5 / 12 ILE A 302
ILE A 308
PHE A 300
ILE A  70
ALA A  24
 None
 0.93A 5lg3E-5k9hA:
undetectable		 5lg3E-5k9hA:
19.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_2
(TUBULIN BETA CHAIN)		 5k9h 0940_GH29
(unidentified) 		4 / 5 LEU A 373
THR A 344
ARG A 403
ARG A 356
 None
None
None
SCN  A 626 (-3.2A)
 1.20A 6ew0B-5k9hA:
undetectable		 6ew0B-5k9hA:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_2
(TUBULIN BETA CHAIN)		 5k9h 0940_GH29
(unidentified) 		4 / 5 LEU A 373
THR A 344
ARG A 403
ARG A 356
 None
None
None
SCN  A 626 (-3.2A)
 1.20A 6ew0D-5k9hA:
undetectable		 6ew0D-5k9hA:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_2
(TUBULIN BETA CHAIN)		 5k9h 0940_GH29
(unidentified) 		4 / 5 LEU A 373
THR A 344
ARG A 403
ARG A 356
 None
None
None
SCN  A 626 (-3.2A)
 1.20A 6ew0H-5k9hA:
undetectable		 6ew0H-5k9hA:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_2
(TUBULIN BETA CHAIN)		 5k9h 0940_GH29
(unidentified) 		4 / 5 LEU A 373
THR A 344
ARG A 403
ARG A 356
 None
None
None
SCN  A 626 (-3.2A)
 1.20A 6ew0I-5k9hA:
undetectable		 6ew0I-5k9hA:
9.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HD6_A_STIA603_1
(TYROSINE-PROTEIN
KINASE ABL1)		 5k9h 0940_GH29
(unidentified) 		4 / 5 LEU A 149
TYR A 153
ILE A 308
MET A  82
 None
 0.95A 6hd6A-5k9hA:
undetectable		 6hd6A-5k9hA:
10.04