SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5k9o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_I_FUAI707_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5k9o HEMAGGLUTININ
(Influenza
A
virus) 		3 / 3 VAL F  56
ALA F  57
HIS F  60
 None
 0.57A 1q23G-5k9oF:
undetectable		 1q23G-5k9oF:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_L_FUAL710_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5k9o HEMAGGLUTININ
(Influenza
A
virus) 		3 / 3 VAL F  56
ALA F  57
HIS F  60
 None
 0.62A 1q23J-5k9oF:
undetectable		 1q23J-5k9oF:
16.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_D_SAMD300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 5k9o HEMAGGLUTININ
(Influenza
A
virus) 		4 / 4 SER F 125
TRP F 127
ASP F 241
ILE F 243
 None
 1.27A 2oxtD-5k9oF:
undetectable		 2oxtD-5k9oF:
17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 5k9o HEMAGGLUTININ
(Influenza
A
virus) 		5 / 11 ASN F 322
GLY F 341
ILE F 335
THR F  37
LEU F 320
 None
 1.42A 3bexC-5k9oF:
undetectable
3bexD-5k9oF:
undetectable		 3bexC-5k9oF:
20.00
3bexD-5k9oF:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD507_1
(HEMOLYTIC LECTIN
CEL-III)		 5k9o HEMAGGLUTININ
(Influenza
A
virus) 		4 / 5 GLU F 340
GLY F 337
TYR F  17
ASP F 441
 None
 1.38A 3w9tD-5k9oF:
undetectable		 3w9tD-5k9oF:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVG_A_SAMA503_0
(D-MYCAROSE
3-C-METHYLTRANSFERAS
E)		 5k9o HEMAGGLUTININ
(Influenza
A
virus) 		5 / 12 THR F 272
ILE F 267
PRO F  58
ALA F  57
ILE F  66
 None
 1.15A 4rvgA-5k9oF:
undetectable		 4rvgA-5k9oF:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AJQ_A_DB8A800_2
(SERINE/THREONINE-PRO
TEIN KINASE 10)		 5k9o HEMAGGLUTININ
(Influenza
A
virus) 		4 / 4 VAL F 384
ILE F 377
ASN F 433
VAL F  40
 None
 1.16A 5ajqA-5k9oF:
undetectable		 5ajqA-5k9oF:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5k9o HEMAGGLUTININ
(Influenza
A
virus) 		4 / 4 LEU F 177
TYR F 148
PRO F 254
ILE F 120
 None
 1.32A 5esgA-5k9oF:
undetectable		 5esgA-5k9oF:
21.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND3_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 5k9o HEMAGGLUTININ
(Influenza
A
virus) 		5 / 12 GLU F  89
LEU F  71
ALA F  67
ARG F 229
ARG F 109
 None
 1.24A 5nd3B-5k9oF:
undetectable		 5nd3B-5k9oF:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ND7_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 5k9o HEMAGGLUTININ
(Influenza
A
virus) 		5 / 12 GLU F  89
LEU F  71
ALA F  67
ARG F 229
ARG F 109
 None
 1.22A 5nd7B-5k9oF:
undetectable		 5nd7B-5k9oF:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_A_EY4A502_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5k9o HEMAGGLUTININ
(Influenza
A
virus) 		4 / 7 ALA F 425
THR F 422
TYR F 423
VAL F 429
 None
 0.86A 6cduA-5k9oF:
2.4
6cduE-5k9oF:
undetectable		 6cduA-5k9oF:
19.38
6cduE-5k9oF:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_H_EY4H500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 5k9o HEMAGGLUTININ
(Influenza
A
virus) 		4 / 7 VAL F 429
ALA F 425
THR F 422
TYR F 423
 None
 0.84A 6cduH-5k9oF:
2.4
6cduI-5k9oF:
2.4		 6cduH-5k9oF:
19.38
6cduI-5k9oF:
19.38