SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5kay'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1291_1
(FICOLIN-2)		 5kay SPELTER
(unidentified) 		4 / 6 LEU A 162
SER A  60
ASP A  57
ASP A  56
 None
 1.12A 2j2pE-5kayA:
undetectable
2j2pF-5kayA:
undetectable		 2j2pE-5kayA:
19.05
2j2pF-5kayA:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILT_H_TRUH800_1
(GLUTAMATE RECEPTOR 2)		 5kay SPELTER
(unidentified) 		3 / 3 ILE A  86
SER A  29
SER A  25
 None
 0.61A 3iltH-5kayA:
undetectable		 3iltH-5kayA:
21.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_A_4CHA191_0
(DEHALOPEROXIDASE A)		 5kay SPELTER
(unidentified) 		4 / 6 PHE A 131
PHE A  87
HIS A 125
VAL A 194
 None
None
ZN  A 301 (-3.1A)
None
 1.26A 3lb3A-5kayA:
undetectable		 3lb3A-5kayA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LB3_B_4CHB192_0
(DEHALOPEROXIDASE A)		 5kay SPELTER
(unidentified) 		4 / 6 PHE A 131
PHE A  87
HIS A 125
VAL A 194
 None
None
ZN  A 301 (-3.1A)
None
 1.20A 3lb3B-5kayA:
undetectable		 3lb3B-5kayA:
22.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_A_GCSA303_1
(CHITOSANASE)		 5kay SPELTER
(unidentified) 		4 / 6 ILE A 159
ASP A 156
ARG A  69
GLY A  67
 None
 1.00A 4oltA-5kayA:
undetectable		 4oltA-5kayA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB303_1
(CHITOSANASE)		 5kay SPELTER
(unidentified) 		4 / 6 ILE A 159
ASP A 156
ARG A  69
GLY A  67
 None
 1.03A 4oltB-5kayA:
undetectable		 4oltB-5kayA:
23.35