SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5kba'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1S9Q_A_CHDA459_0 (ESTROGEN-RELATED RECEPTOR GAMMA)	5kba	DESIGNED PROTEIN ANK1C2 (synthetic construct)	4 / 6	ASP A 82 LEU A 86 VAL A 84 ILE A 87	None	0.98A	1s9qA-5kbaA: undetectable	1s9qA-5kbaA: 25.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XVA_B_ACTB294_0 (GLYCINE N-METHYLTRANSFERASE)	5kba	DESIGNED PROTEIN ANK1C2 (synthetic construct)	4 / 6	ALA A 10 GLU A 9 ILE A 8 LEU A 22	None	0.99A	1xvaA-5kbaA: undetectable 1xvaB-5kbaA: undetectable	1xvaA-5kbaA: 19.45 1xvaB-5kbaA: 19.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WA2_B_SAMB1267_1 (NON-STRUCTURAL PROTEIN 5)	5kba	DESIGNED PROTEIN ANK1C2 (synthetic construct)	3 / 3	SER A 32 HIS A 74 ASP A 94	None	0.78A	2wa2B-5kbaA: undetectable	2wa2B-5kbaA: 24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WYQ_A_SAMA401_1 (TRNA (GUANINE-N(1)-)-METH YLTRANSFERASE)	5kba	DESIGNED PROTEIN ANK1C2 (synthetic construct)	4 / 4	ASP A 35 SER A 34 ASP A 33 HIS A 42	None	1.14A	5wyqB-5kbaA: undetectable	5wyqB-5kbaA: 24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WYQ_A_SAMA401_1 (TRNA (GUANINE-N(1)-)-METH YLTRANSFERASE)	5kba	DESIGNED PROTEIN ANK1C2 (synthetic construct)	4 / 4	ASP A 68 SER A 67 ASP A 66 HIS A 41	None	1.34A	5wyqB-5kbaA: undetectable	5wyqB-5kbaA: 24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WYQ_A_SAMA401_1 (TRNA (GUANINE-N(1)-)-METH YLTRANSFERASE)	5kba	DESIGNED PROTEIN ANK1C2 (synthetic construct)	4 / 4	ASP A 68 SER A 67 ASP A 66 HIS A 75	None	1.04A	5wyqB-5kbaA: undetectable	5wyqB-5kbaA: 24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WYQ_A_SAMA401_1 (TRNA (GUANINE-N(1)-)-METH YLTRANSFERASE)	5kba	DESIGNED PROTEIN ANK1C2 (synthetic construct)	4 / 4	ASP A 101 SER A 100 ASP A 99 HIS A 74	None	1.37A	5wyqB-5kbaA: undetectable	5wyqB-5kbaA: 24.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5WYQ_A_SAMA401_1 (TRNA (GUANINE-N(1)-)-METH YLTRANSFERASE)	5kba	DESIGNED PROTEIN ANK1C2 (synthetic construct)	4 / 4	ASP A 101 SER A 100 ASP A 99 HIS A 108	None	1.03A	5wyqB-5kbaA: undetectable	5wyqB-5kbaA: 24.19

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1S9Q_A_CHDA459_0","ESTROGEN-RELATED RECEPTOR GAMMA","5kba","DESIGNED PROTEIN ANK1C2","synthetic construct",4,"ASP A  82;LEU A  86;VAL A  84;ILE A  87","None","0.98A","1s9qA-5kbaA:undetectable","1s9qA-5kbaA:25.20"],["1XVA_B_ACTB294_0","GLYCINE N-METHYLTRANSFERASE","5kba","DESIGNED PROTEIN ANK1C2","synthetic construct",4,"ALA A  10;GLU A   9;ILE A   8;LEU A  22","None","0.99A","1xvaA-5kbaA:undetectable;1xvaB-5kbaA:undetectable","1xvaA-5kbaA:19.45;1xvaB-5kbaA:19.45"],["2WA2_B_SAMB1267_1","NON-STRUCTURAL PROTEIN 5","5kba","DESIGNED PROTEIN ANK1C2","synthetic construct",3,"SER A  32;HIS A  74;ASP A  94","None","0.78A","2wa2B-5kbaA:undetectable","2wa2B-5kbaA:24.19"],["5WYQ_A_SAMA401_1","TRNA (GUANINE-N(1)-)-METHYLTRANSFERASE","5kba","DESIGNED PROTEIN ANK1C2","synthetic construct",4,"ASP A  35;SER A  34;ASP A  33;HIS A  42","None","1.14A","5wyqB-5kbaA:undetectable","5wyqB-5kbaA:24.19"],["5WYQ_A_SAMA401_1","TRNA (GUANINE-N(1)-)-METHYLTRANSFERASE","5kba","DESIGNED PROTEIN ANK1C2","synthetic construct",4,"ASP A  68;SER A  67;ASP A  66;HIS A  41","None","1.34A","5wyqB-5kbaA:undetectable","5wyqB-5kbaA:24.19"],["5WYQ_A_SAMA401_1","TRNA (GUANINE-N(1)-)-METHYLTRANSFERASE","5kba","DESIGNED PROTEIN ANK1C2","synthetic construct",4,"ASP A  68;SER A  67;ASP A  66;HIS A  75","None","1.04A","5wyqB-5kbaA:undetectable","5wyqB-5kbaA:24.19"],["5WYQ_A_SAMA401_1","TRNA (GUANINE-N(1)-)-METHYLTRANSFERASE","5kba","DESIGNED PROTEIN ANK1C2","synthetic construct",4,"ASP A 101;SER A 100;ASP A  99;HIS A  74","None","1.37A","5wyqB-5kbaA:undetectable","5wyqB-5kbaA:24.19"],["5WYQ_A_SAMA401_1","TRNA (GUANINE-N(1)-)-METHYLTRANSFERASE","5kba","DESIGNED PROTEIN ANK1C2","synthetic construct",4,"ASP A 101;SER A 100;ASP A  99;HIS A 108","None","1.03A","5wyqB-5kbaA:undetectable","5wyqB-5kbaA:24.19"]]