SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5kbc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM9_A_9CRA201_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5kbc DSBA
(Chlamydia
trachomatis) 		3 / 3 GLN A 149
ILE A 137
HIS A  88
 None
 0.71A 1fm9A-5kbcA:
undetectable		 1fm9A-5kbcA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K74_A_9CRA463_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5kbc DSBA
(Chlamydia
trachomatis) 		3 / 3 GLN A 149
ILE A 137
HIS A  88
 None
 0.73A 1k74A-5kbcA:
undetectable		 1k74A-5kbcA:
22.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXF_B_DZPB2001_1
(SERUM ALBUMIN)		 5kbc DSBA
(Chlamydia
trachomatis) 		5 / 12 LEU A 155
ASN A 158
TYR A  98
LEU A  66
GLU A  35
 None
 1.10A 2bxfB-5kbcA:
undetectable		 2bxfB-5kbcA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_DXCC576_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 5kbc DSBA
(Chlamydia
trachomatis) 		4 / 8 PRO A 119
ALA A 123
ALA A 126
ILE A 143
 None
 0.84A 3dtuC-5kbcA:
undetectable
3dtuD-5kbcA:
undetectable		 3dtuC-5kbcA:
14.64
3dtuD-5kbcA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAH_A_ACTA1002_0
(ACTIN, ALPHA
SKELETAL MUSCLE
FORMIN-LIKE PROTEIN
3)		 5kbc DSBA
(Chlamydia
trachomatis) 		4 / 5 THR A 174
GLN A 169
GLU A 183
THR A 172
 None
 1.46A 4eahA-5kbcA:
undetectable
4eahE-5kbcA:
undetectable
4eahG-5kbcA:
undetectable		 4eahA-5kbcA:
19.85
4eahE-5kbcA:
19.85
4eahG-5kbcA:
17.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z12_B_9CRB501_2
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5kbc DSBA
(Chlamydia
trachomatis) 		3 / 3 GLN A 149
ILE A 137
HIS A  88
 None
 0.71A 5z12B-5kbcA:
undetectable		 5z12B-5kbcA:
19.19