SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5kbe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3APW_A_DP0A190_1 (ALPHA-1-ACID GLYCOPROTEIN 2)	5kbe	MOPR (Acinetobacter calcoaceticus)	5 / 12	TYR A 176 PHE A 99 ILE A 191 ALA A 83 SER A 166	IPH A 602 (-4.8A) IPH A 602 ( 4.8A) None None IPH A 602 (-3.6A)	1.07A	3apwA-5kbeA: undetectable	3apwA-5kbeA: 22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KL3_A_DHIA403_0 (GLUCURONOXYLANASE XYNC)	5kbe	MOPR (Acinetobacter calcoaceticus)	4 / 4	GLY A 75 TYR A 161 GLY A 79 ASP A 82	None IPH A 602 ( 4.8A) None None	1.22A	3kl3A-5kbeA: undetectable	3kl3A-5kbeA: 21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M5C_B_TA1B502_1 (TUBULIN BETA-2B CHAIN)	5kbe	MOPR (Acinetobacter calcoaceticus)	5 / 12	ASP A 82 LEU A 159 ALA A 162 SER A 166 GLY A 107	None None IPH A 602 ( 3.9A) IPH A 602 (-3.6A) None	1.14A	5m5cB-5kbeA: undetectable	5m5cB-5kbeA: 18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5M5C_E_TA1E502_1 (TUBULIN BETA-2B CHAIN)	5kbe	MOPR (Acinetobacter calcoaceticus)	5 / 10	ASP A 82 LEU A 159 ALA A 162 SER A 166 GLY A 107	None None IPH A 602 ( 3.9A) IPH A 602 (-3.6A) None	1.14A	5m5cE-5kbeA: undetectable	5m5cE-5kbeA: 18.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6G1P_A_ACTA403_0 (ADP-RIBOSYLHYDROLASE LIKE 2)	5kbe	MOPR (Acinetobacter calcoaceticus)	3 / 3	TYR A 59 ASP A 57 GLN A 60	None	0.86A	6g1pA-5kbeA: undetectable	6g1pA-5kbeA: 20.75

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3APW_A_DP0A190_1","ALPHA-1-ACID GLYCOPROTEIN 2","5kbe","MOPR","Acinetobacter calcoaceticus",5,"TYR A 176;PHE A  99;ILE A 191;ALA A  83;SER A 166","IPH A 602 (-4.8A);IPH A 602 ( 4.8A);None;None;IPH A 602 (-3.6A)","1.07A","3apwA-5kbeA:undetectable","3apwA-5kbeA:22.13"],["3KL3_A_DHIA403_0","GLUCURONOXYLANASE XYNC","5kbe","MOPR","Acinetobacter calcoaceticus",4,"GLY A  75;TYR A 161;GLY A  79;ASP A  82","None;IPH A 602 ( 4.8A);None;None","1.22A","3kl3A-5kbeA:undetectable","3kl3A-5kbeA:21.41"],["5M5C_B_TA1B502_1","TUBULIN BETA-2B CHAIN","5kbe","MOPR","Acinetobacter calcoaceticus",5,"ASP A  82;LEU A 159;ALA A 162;SER A 166;GLY A 107","None;None;IPH A 602 ( 3.9A);IPH A 602 (-3.6A);None","1.14A","5m5cB-5kbeA:undetectable","5m5cB-5kbeA:18.22"],["5M5C_E_TA1E502_1","TUBULIN BETA-2B CHAIN","5kbe","MOPR","Acinetobacter calcoaceticus",5,"ASP A  82;LEU A 159;ALA A 162;SER A 166;GLY A 107","None;None;IPH A 602 ( 3.9A);IPH A 602 (-3.6A);None","1.14A","5m5cE-5kbeA:undetectable","5m5cE-5kbeA:18.22"],["6G1P_A_ACTA403_0","ADP-RIBOSYLHYDROLASE LIKE 2","5kbe","MOPR","Acinetobacter calcoaceticus",3,"TYR A  59;ASP A  57;GLN A  60","None","0.86A","6g1pA-5kbeA:undetectable","6g1pA-5kbeA:20.75"]]