SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5kc7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX9_B_SALB1340_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5kc7 CEREBELLIN-1
(Homo
sapiens) 		4 / 8 LEU A 133
ARG A 166
THR A 103
ALA A 106
 None
 0.97A 3ax9B-5kc7A:
undetectable		 3ax9B-5kc7A:
8.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_C_SAMC300_1
(PUTATIVE RRNA
METHYLASE)		 5kc7 CEREBELLIN-1
(Homo
sapiens) 		3 / 3 ASN A  71
ASP A  87
GLN A  88
 None
 0.81A 3eeyC-5kc7A:
undetectable		 3eeyC-5kc7A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_D_SAMD300_1
(PUTATIVE RRNA
METHYLASE)		 5kc7 CEREBELLIN-1
(Homo
sapiens) 		3 / 3 ASN A  71
ASP A  87
GLN A  88
 None
 0.82A 3eeyD-5kc7A:
undetectable		 3eeyD-5kc7A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEY_E_SAME300_1
(PUTATIVE RRNA
METHYLASE)		 5kc7 CEREBELLIN-1
(Homo
sapiens) 		3 / 3 ASN A  71
ASP A  87
GLN A  88
 None
 0.81A 3eeyE-5kc7A:
undetectable		 3eeyE-5kc7A:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AWU_A_4CHA502_0
(OXIDOREDUCTASE,
FMN-BINDING)		 5kc7 CEREBELLIN-1
(Homo
sapiens) 		4 / 7 THR A 103
ASN A 134
LEU A 133
PHE A 185
 None
 1.38A 4awuA-5kc7A:
undetectable		 4awuA-5kc7A:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRJ_A_RAPA201_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4
SERINE/THREONINE-PRO
TEIN KINASE MTOR)		 5kc7 CEREBELLIN-1
(Homo
sapiens) 		4 / 8 SER A 186
PHE A 185
THR A 103
PHE A 188
 None
 1.03A 4drjB-5kc7A:
undetectable		 4drjB-5kc7A:
19.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_B_LDPB501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 5kc7 CEREBELLIN-1
(Homo
sapiens) 		4 / 6 PHE A 114
ALA A 167
ALA A 106
PRO A 107
 None
 1.02A 4dtzB-5kc7A:
undetectable		 4dtzB-5kc7A:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWX_A_SAMA301_1
(GLYCINE SARCOSINE
N-METHYLTRANSFERASE)		 5kc7 CEREBELLIN-1
(Homo
sapiens) 		3 / 3 ARG A 150
ASN A  71
ASP A  87
 None
 0.88A 5gwxA-5kc7A:
undetectable		 5gwxA-5kc7A:
18.73