SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5kdj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DG5_A_TOPA201_1
(DIHYDROFOLATE
REDUCTASE)		 5kdj F5/8 TYPE C DOMAIN
PROTEIN
(Clostridium
perfringens) 		5 / 11 ILE B 575
ALA B 616
LEU B 566
PRO B 547
ILE B 573
 None
 1.14A 1dg5A-5kdjB:
undetectable		 1dg5A-5kdjB:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_4
(HIV-1 PROTEASE)		 5kdj F5/8 TYPE C DOMAIN
PROTEIN
(Clostridium
perfringens) 		4 / 4 GLY B 961
ASP B 808
GLY B 965
THR B 988
 None
 1.02A 1hxbB-5kdjB:
undetectable		 1hxbB-5kdjB:
9.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_A_CRNA401_1
(CREATININE
AMIDOHYDROLASE)		 5kdj F5/8 TYPE C DOMAIN
PROTEIN
(Clostridium
perfringens) 		4 / 8 GLU B 771
HIS B 756
HIS B 760
GLU B 757
 ZN  B1103 (-2.5A)
ZN  B1103 (-3.3A)
ZN  B1103 (-3.4A)
ZN  B1103 ( 4.3A)
 0.84A 1v7zA-5kdjB:
undetectable		 1v7zA-5kdjB:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_B_CRNB3401_1
(CREATININE
AMIDOHYDROLASE)		 5kdj F5/8 TYPE C DOMAIN
PROTEIN
(Clostridium
perfringens) 		4 / 8 GLU B 771
HIS B 756
HIS B 760
GLU B 757
 ZN  B1103 (-2.5A)
ZN  B1103 (-3.3A)
ZN  B1103 (-3.4A)
ZN  B1103 ( 4.3A)
 0.85A 1v7zB-5kdjB:
undetectable		 1v7zB-5kdjB:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V7Z_C_CRNC4401_1
(CREATININE
AMIDOHYDROLASE)		 5kdj F5/8 TYPE C DOMAIN
PROTEIN
(Clostridium
perfringens) 		4 / 8 GLU B 771
HIS B 756
HIS B 760
GLU B 757
 ZN  B1103 (-2.5A)
ZN  B1103 (-3.3A)
ZN  B1103 (-3.4A)
ZN  B1103 ( 4.3A)
 0.85A 1v7zC-5kdjB:
undetectable		 1v7zC-5kdjB:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_1
(VP39)		 5kdj F5/8 TYPE C DOMAIN
PROTEIN
(Clostridium
perfringens) 		3 / 3 ASP B 871
ARG B 851
ASP B 895
 None
 0.67A 1vptA-5kdjB:
undetectable		 1vptA-5kdjB:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_IMNA301_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 5kdj F5/8 TYPE C DOMAIN
PROTEIN
(Clostridium
perfringens) 		3 / 3 ASP B 837
TYR B 836
LYS B 993
 None
 1.20A 2othA-5kdjB:
undetectable		 2othA-5kdjB:
10.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIV_A_T3A933_1
(ANDROGEN RECEPTOR)		 5kdj F5/8 TYPE C DOMAIN
PROTEIN
(Clostridium
perfringens) 		5 / 9 ILE B 590
GLY B 584
GLU B 581
ASN B 579
GLU B 577
 None
 1.25A 2pivA-5kdjB:
undetectable		 2pivA-5kdjB:
15.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6K_A_ADNA699_1
(CHLORINASE)		 5kdj F5/8 TYPE C DOMAIN
PROTEIN
(Clostridium
perfringens) 		4 / 7 TYR B 908
TYR B 802
PRO B 803
THR B 801
 None
 1.46A 2q6kA-5kdjB:
undetectable		 2q6kA-5kdjB:
16.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WQ5_A_MIYA1120_1
(PHOSPHOLIPASE A2,
ACIDIC)		 5kdj F5/8 TYPE C DOMAIN
PROTEIN
(Clostridium
perfringens) 		4 / 7 GLY B 842
ARG B 846
PHE B 780
PHE B 781
 None
 0.96A 2wq5A-5kdjB:
undetectable		 2wq5A-5kdjB:
8.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_A_CRNA303_1
(CREATININE
AMIDOHYDROLASE)		 5kdj F5/8 TYPE C DOMAIN
PROTEIN
(Clostridium
perfringens) 		4 / 8 GLU B 771
HIS B 756
HIS B 760
GLU B 757
 ZN  B1103 (-2.5A)
ZN  B1103 (-3.3A)
ZN  B1103 (-3.4A)
ZN  B1103 ( 4.3A)
 0.85A 3a6jA-5kdjB:
undetectable		 3a6jA-5kdjB:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_B_CRNB304_1
(CREATININE
AMIDOHYDROLASE)		 5kdj F5/8 TYPE C DOMAIN
PROTEIN
(Clostridium
perfringens) 		4 / 7 GLU B 771
HIS B 756
HIS B 760
GLU B 757
 ZN  B1103 (-2.5A)
ZN  B1103 (-3.3A)
ZN  B1103 (-3.4A)
ZN  B1103 ( 4.3A)
 0.83A 3a6jB-5kdjB:
undetectable		 3a6jB-5kdjB:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_C_CRNC305_1
(CREATININE
AMIDOHYDROLASE)		 5kdj F5/8 TYPE C DOMAIN
PROTEIN
(Clostridium
perfringens) 		4 / 8 GLU B 771
HIS B 756
HIS B 760
GLU B 757
 ZN  B1103 (-2.5A)
ZN  B1103 (-3.3A)
ZN  B1103 (-3.4A)
ZN  B1103 ( 4.3A)
 0.82A 3a6jC-5kdjB:
undetectable		 3a6jC-5kdjB:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_E_CRNE306_1
(CREATININE
AMIDOHYDROLASE)		 5kdj F5/8 TYPE C DOMAIN
PROTEIN
(Clostridium
perfringens) 		4 / 8 GLU B 771
HIS B 756
HIS B 760
GLU B 757
 ZN  B1103 (-2.5A)
ZN  B1103 (-3.3A)
ZN  B1103 (-3.4A)
ZN  B1103 ( 4.3A)
 0.86A 3a6jE-5kdjB:
undetectable		 3a6jE-5kdjB:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A6J_F_CRNF307_1
(CREATININE
AMIDOHYDROLASE)		 5kdj F5/8 TYPE C DOMAIN
PROTEIN
(Clostridium
perfringens) 		4 / 8 GLU B 771
HIS B 756
HIS B 760
GLU B 757
 ZN  B1103 (-2.5A)
ZN  B1103 (-3.3A)
ZN  B1103 (-3.4A)
ZN  B1103 ( 4.3A)
 0.82A 3a6jF-5kdjB:
undetectable		 3a6jF-5kdjB:
17.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJ8_C_SPMC500_1
(DIAMINE
ACETYLTRANSFERASE 1)		 5kdj F5/8 TYPE C DOMAIN
PROTEIN
(Clostridium
perfringens) 		4 / 6 ASP B 594
LEU B 550
LEU B 498
TRP B 521
 None
 0.87A 3bj8C-5kdjB:
undetectable
3bj8D-5kdjB:
undetectable		 3bj8C-5kdjB:
15.03
3bj8D-5kdjB:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILT_H_TRUH800_1
(GLUTAMATE RECEPTOR 2)		 5kdj F5/8 TYPE C DOMAIN
PROTEIN
(Clostridium
perfringens) 		3 / 3 ILE B1000
SER B 943
SER B 941
 None
 0.62A 3iltH-5kdjB:
undetectable		 3iltH-5kdjB:
18.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_B_HAEB271_1
(COLLAGENASE 3)		 5kdj F5/8 TYPE C DOMAIN
PROTEIN
(Clostridium
perfringens) 		3 / 3 HIS B 756
GLU B 757
HIS B 760
 ZN  B1103 (-3.3A)
ZN  B1103 ( 4.3A)
ZN  B1103 (-3.4A)
 0.19A 3kecB-5kdjB:
2.4		 3kecB-5kdjB:
13.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_A_ACHA301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5kdj F5/8 TYPE C DOMAIN
PROTEIN
(Clostridium
perfringens) 		4 / 7 TYR B 963
THR B 801
TYR B 908
TYR B 802
 None
 1.46A 3wipA-5kdjB:
undetectable
3wipB-5kdjB:
undetectable		 3wipA-5kdjB:
15.21
3wipB-5kdjB:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WIP_F_ACHF301_0
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 5kdj F5/8 TYPE C DOMAIN
PROTEIN
(Clostridium
perfringens) 		4 / 7 TYR B 963
THR B 801
TYR B 908
TYR B 802
 None
 1.47A 3wipF-5kdjB:
undetectable
3wipG-5kdjB:
undetectable		 3wipF-5kdjB:
15.21
3wipG-5kdjB:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1478_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5kdj F5/8 TYPE C DOMAIN
PROTEIN
(Clostridium
perfringens) 		4 / 7 GLY B 525
THR B 524
ILE B 523
PHE B 664
 None
 0.83A 4acaC-5kdjB:
undetectable		 4acaC-5kdjB:
24.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_1
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 5kdj F5/8 TYPE C DOMAIN
PROTEIN
(Clostridium
perfringens) 		3 / 3 ASP B 871
ARG B 851
ASP B 895
 None
 0.86A 4fzvA-5kdjB:
undetectable		 4fzvA-5kdjB:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R29_D_SAMD301_0
(UNCHARACTERIZED
PROTEIN)		 5kdj F5/8 TYPE C DOMAIN
PROTEIN
(Clostridium
perfringens) 		5 / 12 ILE B 692
ALA B 693
MET B 696
GLY B 697
PHE B 701
 None
 1.02A 4r29D-5kdjB:
undetectable		 4r29D-5kdjB:
15.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_C_377C401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5kdj F5/8 TYPE C DOMAIN
PROTEIN
(Clostridium
perfringens) 		4 / 6 TYR B 907
GLU B 956
TYR B 990
LEU B 953
 None
 1.26A 4twdB-5kdjB:
undetectable
4twdC-5kdjB:
undetectable		 4twdB-5kdjB:
17.31
4twdC-5kdjB:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_E_377E401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5kdj F5/8 TYPE C DOMAIN
PROTEIN
(Clostridium
perfringens) 		4 / 6 TYR B 907
GLU B 956
TYR B 990
LEU B 953
 None
 1.29A 4twdD-5kdjB:
undetectable
4twdE-5kdjB:
undetectable		 4twdD-5kdjB:
17.31
4twdE-5kdjB:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_G_377G401_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5kdj F5/8 TYPE C DOMAIN
PROTEIN
(Clostridium
perfringens) 		4 / 6 TYR B 907
GLU B 956
TYR B 990
LEU B 953
 None
 1.30A 4twdF-5kdjB:
undetectable
4twdG-5kdjB:
undetectable		 4twdF-5kdjB:
17.31
4twdG-5kdjB:
17.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNW_B_RTZB602_2
(CYTOCHROME P450 2D6)		 5kdj F5/8 TYPE C DOMAIN
PROTEIN
(Clostridium
perfringens) 		3 / 3 GLU B 845
ILE B 861
ALA B 869
 None
 0.59A 4wnwB-5kdjB:
undetectable		 4wnwB-5kdjB:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJQ_D_ERYD1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 5kdj F5/8 TYPE C DOMAIN
PROTEIN
(Clostridium
perfringens) 		5 / 12 THR B 598
SER B 506
MET B 696
ILE B 692
PHE B 762
 None
 1.24A 4zjqD-5kdjB:
0.5		 4zjqD-5kdjB:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_A_SAMA301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 5kdj F5/8 TYPE C DOMAIN
PROTEIN
(Clostridium
perfringens) 		5 / 12 ASP B 871
ALA B 868
LYS B 514
PHE B 848
GLU B 850
 None
 1.27A 5hfjA-5kdjB:
undetectable		 5hfjA-5kdjB:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5kdj F5/8 TYPE C DOMAIN
PROTEIN
(Clostridium
perfringens) 		3 / 3 TYR B 691
TYR B 834
SER B 783
 None
 0.89A 5iktB-5kdjB:
undetectable		 5iktB-5kdjB:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J2T_C_VLBC503_1
(TUBULIN BETA-2B
CHAIN
TUBULIN ALPHA-1B
CHAIN)		 5kdj F5/8 TYPE C DOMAIN
PROTEIN
(Clostridium
perfringens) 		5 / 9 VAL B 964
PHE B 966
THR B 988
TYR B 985
LEU B 940
 None
 1.44A 5j2tB-5kdjB:
undetectable		 5j2tB-5kdjB:
20.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TIX_B_OQRB302_0
(SULFOTRANSFERASE)		 5kdj F5/8 TYPE C DOMAIN
PROTEIN
(Clostridium
perfringens) 		5 / 10 MET B 696
ILE B 692
VAL B 515
PHE B 713
GLU B 509
 None
 1.46A 5tixB-5kdjB:
undetectable		 5tixB-5kdjB:
15.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W7P_A_SAMA501_0
(OXAC)		 5kdj F5/8 TYPE C DOMAIN
PROTEIN
(Clostridium
perfringens) 		5 / 12 PHE B 596
ALA B 561
GLY B 560
LEU B 549
ASP B 594
 None
 0.95A 5w7pA-5kdjB:
undetectable		 5w7pA-5kdjB:
23.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C2M_D_SUED1202_0
(NS3 PROTEASE)		 5kdj F5/8 TYPE C DOMAIN
PROTEIN
(Clostridium
perfringens) 		6 / 12 VAL B 589
ILE B 613
GLY B 525
ARG B 529
ALA B 528
ALA B 616
 None
 1.36A 6c2mD-5kdjB:
undetectable		 6c2mD-5kdjB:
7.28