SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5kdm'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QCA_A_FUAA221_1
(TYPE III
CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5kdm MAJOR TEGUMENT
PROTEIN
(Human
gammaherpesvirus
4) 		4 / 7 CYH D 505
SER D 506
PHE D 400
LEU D 551
 None
 1.13A 1qcaA-5kdmD:
undetectable		 1qcaA-5kdmD:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA11_1
(CES1 PROTEIN)		 5kdm MAJOR TEGUMENT
PROTEIN
(Human
gammaherpesvirus
4) 		4 / 8 LEU D 551
GLY D 550
LEU D 466
PRO D 572
 None
 0.95A 1ya4A-5kdmD:
undetectable		 1ya4A-5kdmD:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOI_C_FRDC305_2
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 5kdm MAJOR TEGUMENT
PROTEIN
(Human
gammaherpesvirus
4) 		4 / 5 LEU D 455
PRO D 503
VAL D 451
ILE D 452
 None
 0.94A 2aoiB-5kdmD:
undetectable		 2aoiB-5kdmD:
23.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_B_CHDB928_0
(FERROCHELATASE)		 5kdm MAJOR TEGUMENT
PROTEIN
(Human
gammaherpesvirus
4) 		5 / 12 LEU D 468
LEU D 471
LEU D 455
VAL D 451
VAL D 576
 None
 1.32A 2qd4B-5kdmD:
undetectable		 2qd4B-5kdmD:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_C_CHDC1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5kdm MAJOR TEGUMENT
PROTEIN
(Human
gammaherpesvirus
4) 		4 / 5 PHE D 500
PHE D 553
LEU D 551
PHE D 578
 None
 1.16A 2y69C-5kdmD:
undetectable
2y69J-5kdmD:
undetectable		 2y69C-5kdmD:
21.64
2y69J-5kdmD:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_P_CHDP1265_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5kdm MAJOR TEGUMENT
PROTEIN
(Human
gammaherpesvirus
4) 		4 / 5 PHE D 500
PHE D 553
LEU D 551
PHE D 578
 None
 1.18A 2y69P-5kdmD:
undetectable
2y69W-5kdmD:
undetectable		 2y69P-5kdmD:
21.64
2y69W-5kdmD:
15.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_P_CHDP1271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5kdm MAJOR TEGUMENT
PROTEIN
(Human
gammaherpesvirus
4) 		4 / 6 PHE D 500
PHE D 553
LEU D 551
PHE D 578
 None
 1.17A 3ablP-5kdmD:
undetectable
3ablW-5kdmD:
undetectable		 3ablP-5kdmD:
21.64
3ablW-5kdmD:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5kdm MAJOR TEGUMENT
PROTEIN
(Human
gammaherpesvirus
4) 		4 / 5 PHE D 500
PHE D 553
LEU D 551
PHE D 578
 None
 1.19A 3abmC-5kdmD:
undetectable
3abmJ-5kdmD:
undetectable		 3abmC-5kdmD:
21.64
3abmJ-5kdmD:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_C_CHDC271_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5kdm MAJOR TEGUMENT
PROTEIN
(Human
gammaherpesvirus
4) 		4 / 5 PHE D 500
PHE D 553
LEU D 551
PHE D 578
 None
 1.12A 3ag3C-5kdmD:
undetectable
3ag3J-5kdmD:
undetectable		 3ag3C-5kdmD:
21.64
3ag3J-5kdmD:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AI8_B_HNQB255_1
(CATHEPSIN B)		 5kdm MAJOR TEGUMENT
PROTEIN
(Human
gammaherpesvirus
4) 		4 / 6 GLN D 514
GLY D 516
HIS D 392
CYH D 438
 None
 1.22A 3ai8B-5kdmD:
undetectable		 3ai8B-5kdmD:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGG_A_CHDA211_0
(CMER)		 5kdm MAJOR TEGUMENT
PROTEIN
(Human
gammaherpesvirus
4) 		4 / 7 PHE D 467
PHE D 570
SER D 544
TYR D 393
 None
 1.46A 3hggA-5kdmD:
2.5		 3hggA-5kdmD:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNY_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 5kdm MAJOR TEGUMENT
PROTEIN
(Human
gammaherpesvirus
4) 		5 / 12 VAL D 475
ASP D 474
LEU D 394
LEU D 466
LEU D 455
 None
 1.19A 5hnyB-5kdmD:
undetectable		 5hnyB-5kdmD:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JO9_A_SORA302_0
(RIBITOL
2-DEHYDROGENASE)		 5kdm MAJOR TEGUMENT
PROTEIN
(Human
gammaherpesvirus
4) 		5 / 12 TYR D 388
LEU D 455
GLY D 456
PHE D 578
LEU D 551
 None
 1.29A 5jo9A-5kdmD:
undetectable		 5jo9A-5kdmD:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFP_A_8W5A804_2
(GLUCOCORTICOID
RECEPTOR)		 5kdm MAJOR TEGUMENT
PROTEIN
(Human
gammaherpesvirus
4) 		4 / 4 LEU D 394
MET D 566
ILE D 439
LEU D 525
 None
 1.20A 5nfpA-5kdmD:
undetectable		 5nfpA-5kdmD:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OG9_A_TESA504_1
(-)		 5kdm MAJOR TEGUMENT
PROTEIN
(Human
gammaherpesvirus
4) 		5 / 8 ILE D 510
VAL D 541
ALA D 527
LEU D 525
THR D 523
 None
 1.18A 5og9A-5kdmD:
undetectable		 5og9A-5kdmD:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5kdm MAJOR TEGUMENT
PROTEIN
(Human
gammaherpesvirus
4) 		4 / 5 PHE D 500
PHE D 553
LEU D 551
PHE D 578
 None
 1.14A 5wauC-5kdmD:
undetectable
5wauJ-5kdmD:
undetectable		 5wauC-5kdmD:
21.64
5wauJ-5kdmD:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5kdm MAJOR TEGUMENT
PROTEIN
(Human
gammaherpesvirus
4) 		4 / 5 PHE D 500
PHE D 553
LEU D 551
PHE D 578
 None
 1.12A 5wauc-5kdmD:
undetectable
5wauj-5kdmD:
undetectable		 5wauc-5kdmD:
21.64
5wauj-5kdmD:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC308_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5kdm MAJOR TEGUMENT
PROTEIN
(Human
gammaherpesvirus
4) 		4 / 5 PHE D 500
PHE D 553
LEU D 551
PHE D 578
 None
 1.12A 5xdqC-5kdmD:
undetectable
5xdqJ-5kdmD:
undetectable		 5xdqC-5kdmD:
21.64
5xdqJ-5kdmD:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5kdm MAJOR TEGUMENT
PROTEIN
(Human
gammaherpesvirus
4) 		4 / 5 PHE D 500
PHE D 553
LEU D 551
PHE D 578
 None
 1.11A 5xdqP-5kdmD:
undetectable
5xdqW-5kdmD:
undetectable		 5xdqP-5kdmD:
21.64
5xdqW-5kdmD:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5kdm MAJOR TEGUMENT
PROTEIN
(Human
gammaherpesvirus
4) 		4 / 6 PHE D 500
PHE D 553
LEU D 551
PHE D 578
 None
 1.09A 5z84P-5kdmD:
undetectable
5z84W-5kdmD:
undetectable		 5z84P-5kdmD:
21.64
5z84W-5kdmD:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5kdm MAJOR TEGUMENT
PROTEIN
(Human
gammaherpesvirus
4) 		4 / 6 PHE D 500
PHE D 553
LEU D 551
PHE D 578
 None
 1.11A 5z85P-5kdmD:
undetectable
5z85W-5kdmD:
undetectable		 5z85P-5kdmD:
21.64
5z85W-5kdmD:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5kdm MAJOR TEGUMENT
PROTEIN
(Human
gammaherpesvirus
4) 		4 / 6 PHE D 500
PHE D 553
LEU D 551
PHE D 578
 None
 1.10A 5z86C-5kdmD:
undetectable
5z86J-5kdmD:
undetectable		 5z86C-5kdmD:
21.64
5z86J-5kdmD:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5kdm MAJOR TEGUMENT
PROTEIN
(Human
gammaherpesvirus
4) 		4 / 6 PHE D 500
PHE D 553
LEU D 551
PHE D 578
 None
 1.07A 5z86P-5kdmD:
undetectable
5z86W-5kdmD:
undetectable		 5z86P-5kdmD:
21.64
5z86W-5kdmD:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5kdm MAJOR TEGUMENT
PROTEIN
(Human
gammaherpesvirus
4) 		4 / 6 PHE D 500
PHE D 553
LEU D 551
PHE D 578
 None
 1.12A 5zcoP-5kdmD:
undetectable
5zcoW-5kdmD:
undetectable		 5zcoP-5kdmD:
21.64
5zcoW-5kdmD:
13.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5kdm MAJOR TEGUMENT
PROTEIN
(Human
gammaherpesvirus
4) 		4 / 6 PHE D 500
PHE D 553
LEU D 551
PHE D 578
 None
 1.10A 5zcpP-5kdmD:
undetectable
5zcpW-5kdmD:
undetectable		 5zcpP-5kdmD:
21.64
5zcpW-5kdmD:
13.70