SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ken'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 5ken EBOLA SURFACE
GLYCOPROTEIN, GP1
EBOLA SURFACE
GLYCOPROTEIN, GP2
(Zaire
ebolavirus;
Zaire
ebolavirus) 		3 / 3 SER A  58
HIS A  39
ASP B 552
 None
 0.72A 2oxtA-5kenA:
undetectable		 2oxtA-5kenA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W3M_B_FOLB1188_0
(DIHYDROFOLATE
REDUCTASE)		 5ken EBOLA SURFACE
GLYCOPROTEIN, GP1
(Zaire
ebolavirus) 		5 / 12 ALA A  82
GLU A 178
PHE A 160
PHE A 176
TYR A 232
 None
 1.28A 2w3mB-5kenA:
undetectable		 2w3mB-5kenA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z0Y_A_SAMA300_0
(PUTATIVE
UNCHARACTERIZED
PROTEIN TTHA0657)		 5ken EBOLA SURFACE
GLYCOPROTEIN, GP1
EBOLA SURFACE
GLYCOPROTEIN, GP2
(Zaire
ebolavirus;
Zaire
ebolavirus) 		5 / 9 GLY A  67
GLY A 102
LEU B 561
ILE B 555
ALA B 562
 None
 0.97A 2z0yA-5kenA:
undetectable		 2z0yA-5kenA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_B_EPAB3_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 5ken EBOLA SURFACE
GLYCOPROTEIN, GP1
EBOLA SURFACE
GLYCOPROTEIN, GP2
(Zaire
ebolavirus) 		5 / 12 LEU A  68
GLN B 551
VAL A  66
LEU A 184
ILE A  38
 None
 1.09A 3gwxB-5kenA:
undetectable		 3gwxB-5kenA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KKZ_B_SAMB302_0
(UNCHARACTERIZED
PROTEIN Q5LES9)		 5ken EBOLA SURFACE
GLYCOPROTEIN, GP1
EBOLA SURFACE
GLYCOPROTEIN, GP2
(Zaire
ebolavirus;
Zaire
ebolavirus) 		5 / 12 ARG B 559
GLY A  72
GLY A 179
PHE A 176
ALA A 105
 None
 1.02A 3kkzB-5kenB:
undetectable		 3kkzB-5kenB:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO201_1
(PROTEIN S100-A4)		 5ken EBOLA SURFACE
GLYCOPROTEIN, GP1
(Zaire
ebolavirus) 		4 / 8 GLY A 157
PHE A 225
GLY A  87
PHE A  88
 NAG  A 401 ( 4.2A)
None
None
None
 0.92A 3ko0O-5kenA:
undetectable
3ko0Q-5kenA:
undetectable		 3ko0O-5kenA:
15.50
3ko0Q-5kenA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ken EBOLA SURFACE
GLYCOPROTEIN, GP2
(Zaire
ebolavirus) 		3 / 3 GLN B 521
THR B 520
LEU B 585
 None
 0.51A 3ondA-5kenB:
undetectable		 3ondA-5kenB:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ken EBOLA SURFACE
GLYCOPROTEIN, GP2
(Zaire
ebolavirus) 		3 / 3 GLN B 521
THR B 520
LEU B 585
 None
 0.50A 3ondB-5kenB:
undetectable		 3ondB-5kenB:
12.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_A_BEZA701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 5ken C4G7 VARIABLE FAB
DOMAIN HEAVY CHAIN
(Homo
sapiens) 		5 / 12 GLU C  12
GLY C   8
THR C 107
SER C  21
GLU C   6
 None
 1.49A 3r75A-5kenC:
undetectable		 3r75A-5kenC:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R75_B_BEZB701_0
(ANTHRANILATE/PARA-AM
INOBENZOATE
SYNTHASES COMPONENT
I)		 5ken C4G7 VARIABLE FAB
DOMAIN HEAVY CHAIN
(Homo
sapiens) 		5 / 12 GLU C  12
GLY C   8
THR C 107
SER C  21
GLU C   6
 None
 1.48A 3r75B-5kenC:
undetectable		 3r75B-5kenC:
12.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SNF_A_ACTA110_0
(PROTEIN P-30)		 5ken EBOLA SURFACE
GLYCOPROTEIN, GP1
EBOLA SURFACE
GLYCOPROTEIN, GP2
(Zaire
ebolavirus;
Zaire
ebolavirus) 		4 / 5 ILE A  33
THR B 565
THR B 566
PHE A 183
 None
None
NAG  A 401 ( 4.7A)
None
 1.20A 3snfA-5kenA:
undetectable		 3snfA-5kenA:
15.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZDY_A_1YNA602_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5ken EBOLA SURFACE
GLYCOPROTEIN, GP1
(Zaire
ebolavirus) 		3 / 3 ALA A 166
TYR A 162
PRO A  94
 None
 0.65A 4zdyA-5kenA:
undetectable		 4zdyA-5kenA:
17.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_D_6K9D502_0
(TUBULIN BETA-2B
CHAIN)		 5ken EBOLA SURFACE
GLYCOPROTEIN, GP1
(Zaire
ebolavirus) 		5 / 11 GLN A 251
ASN A 107
ASP A  78
THR A  77
LEU A 256
 None
 1.39A 5jh7D-5kenA:
undetectable		 5jh7D-5kenA:
22.32
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 5ken EBOLA SURFACE
GLYCOPROTEIN, GP2
(Zaire
ebolavirus) 		4 / 7 LEU B 515
TYR B 517
THR B 520
LEU B 558
 None
 0.80A 5jq7B-5kenB:
8.7		 5jq7B-5kenB:
99.12
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5JQ7_B_T0RB705_2
(ENVELOPE
GLYCOPROTEIN 2)		 5ken EBOLA SURFACE
GLYCOPROTEIN, GP2
(Zaire
ebolavirus) 		4 / 7 TYR B 517
THR B 519
THR B 520
LEU B 558
 None
 0.80A 5jq7B-5kenB:
8.7		 5jq7B-5kenB:
99.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ken C13C6 VARIABLE FAB
DOMAIN LIGHT CHAIN
(Homo
sapiens) 		4 / 6 GLN I  89
PHE I  87
LEU I  73
PHE I  62
 None
 0.94A 5z84P-5kenI:
undetectable
5z84W-5kenI:
undetectable		 5z84P-5kenI:
17.44
5z84W-5kenI:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ken C13C6 VARIABLE FAB
DOMAIN LIGHT CHAIN
(Homo
sapiens) 		4 / 7 GLN I  89
PHE I  87
LEU I  73
PHE I  62
 None
 0.95A 5z85C-5kenI:
undetectable
5z85J-5kenI:
undetectable		 5z85C-5kenI:
17.44
5z85J-5kenI:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ken C13C6 VARIABLE FAB
DOMAIN LIGHT CHAIN
(Homo
sapiens) 		4 / 6 GLN I  89
PHE I  87
LEU I  73
PHE I  62
 None
 0.94A 5z85P-5kenI:
undetectable
5z85W-5kenI:
undetectable		 5z85P-5kenI:
17.44
5z85W-5kenI:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ken C13C6 VARIABLE FAB
DOMAIN LIGHT CHAIN
(Homo
sapiens) 		4 / 6 GLN I  89
PHE I  87
LEU I  73
PHE I  62
 None
 1.01A 5z86C-5kenI:
undetectable
5z86J-5kenI:
undetectable		 5z86C-5kenI:
17.44
5z86J-5kenI:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ken C13C6 VARIABLE FAB
DOMAIN LIGHT CHAIN
(Homo
sapiens) 		4 / 6 GLN I  89
PHE I  87
LEU I  73
PHE I  62
 None
 0.96A 5z86P-5kenI:
undetectable
5z86W-5kenI:
undetectable		 5z86P-5kenI:
17.44
5z86W-5kenI:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP305_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ken C13C6 VARIABLE FAB
DOMAIN LIGHT CHAIN
(Homo
sapiens) 		4 / 6 GLN I  89
PHE I  87
LEU I  73
PHE I  62
 None
 0.93A 5zcoP-5kenI:
undetectable
5zcoW-5kenI:
undetectable		 5zcoP-5kenI:
17.44
5zcoW-5kenI:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ken C13C6 VARIABLE FAB
DOMAIN LIGHT CHAIN
(Homo
sapiens) 		4 / 6 GLN I  89
PHE I  87
LEU I  73
PHE I  62
 None
 0.95A 5zcpC-5kenI:
undetectable
5zcpJ-5kenI:
undetectable		 5zcpC-5kenI:
17.44
5zcpJ-5kenI:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ken C13C6 VARIABLE FAB
DOMAIN LIGHT CHAIN
(Homo
sapiens) 		4 / 6 GLN I  89
PHE I  87
LEU I  73
PHE I  62
 None
 0.89A 5zcpP-5kenI:
undetectable
5zcpW-5kenI:
undetectable		 5zcpP-5kenI:
17.44
5zcpW-5kenI:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ken C13C6 VARIABLE FAB
DOMAIN LIGHT CHAIN
(Homo
sapiens) 		4 / 7 GLN I  89
PHE I  87
LEU I  73
PHE I  62
 None
 0.98A 5zcqC-5kenI:
undetectable
5zcqJ-5kenI:
undetectable		 5zcqC-5kenI:
17.44
5zcqJ-5kenI:
19.44
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 5ken EBOLA SURFACE
GLYCOPROTEIN, GP1
EBOLA SURFACE
GLYCOPROTEIN, GP2
(Zaire
ebolavirus) 		7 / 10 ARG A  64
VAL A  66
LEU A 184
LEU A 186
THR B 519
MET B 548
LEU B 558
 None
 1.24A 6f5uA-5kenA:
23.7
6f5uB-5kenA:
undetectable		 6f5uA-5kenA:
98.67
6f5uB-5kenA:
15.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 5ken EBOLA SURFACE
GLYCOPROTEIN, GP1
EBOLA SURFACE
GLYCOPROTEIN, GP2
(Zaire
ebolavirus) 		7 / 10 ARG A  64
VAL A  66
LEU A 184
LEU A 186
TYR B 517
THR B 519
LEU B 558
 None
 1.01A 6f5uA-5kenA:
23.7
6f5uB-5kenA:
undetectable		 6f5uA-5kenA:
98.67
6f5uB-5kenA:
15.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 5ken EBOLA SURFACE
GLYCOPROTEIN, GP1
EBOLA SURFACE
GLYCOPROTEIN, GP2
(Zaire
ebolavirus) 		6 / 10 VAL A  66
LEU A 184
LEU A 186
LEU B 515
MET B 548
LEU B 558
 None
 1.15A 6f5uA-5kenA:
23.7
6f5uB-5kenA:
undetectable		 6f5uA-5kenA:
98.67
6f5uB-5kenA:
15.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 5ken EBOLA SURFACE
GLYCOPROTEIN, GP1
EBOLA SURFACE
GLYCOPROTEIN, GP2
(Zaire
ebolavirus) 		6 / 10 VAL A  66
LEU A 184
LEU A 186
LEU B 515
TYR B 517
LEU B 558
 None
 0.96A 6f5uA-5kenA:
23.7
6f5uB-5kenA:
undetectable		 6f5uA-5kenA:
98.67
6f5uB-5kenA:
15.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F6I_A_8PRA509_1
(ENVELOPE
GLYCOPROTEIN,GP,GP1
ENVELOPE
GLYCOPROTEIN)		 5ken EBOLA SURFACE
GLYCOPROTEIN, GP1
EBOLA SURFACE
GLYCOPROTEIN, GP2
(Zaire
ebolavirus) 		5 / 12 ARG A  64
LEU A 186
LEU B 515
TYR B 517
LEU B 558
 None
 0.91A 6f6iA-5kenA:
23.7
6f6iB-5kenA:
undetectable		 6f6iA-5kenA:
98.67
6f6iB-5kenA:
15.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F6I_A_8PRA509_1
(ENVELOPE
GLYCOPROTEIN,GP,GP1
ENVELOPE
GLYCOPROTEIN)		 5ken EBOLA SURFACE
GLYCOPROTEIN, GP1
EBOLA SURFACE
GLYCOPROTEIN, GP2
(Zaire
ebolavirus) 		5 / 12 ARG A  64
LEU A 186
LEU B 515
TYR B 517
MET B 548
 None
 0.90A 6f6iA-5kenA:
23.7
6f6iB-5kenA:
undetectable		 6f6iA-5kenA:
98.67
6f6iB-5kenA:
15.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F6I_A_8PRA509_1
(ENVELOPE
GLYCOPROTEIN,GP,GP1
ENVELOPE
GLYCOPROTEIN)		 5ken EBOLA SURFACE
GLYCOPROTEIN, GP1
EBOLA SURFACE
GLYCOPROTEIN, GP2
(Zaire
ebolavirus) 		5 / 12 ARG A  64
LEU A 186
TYR B 517
THR B 519
LEU B 558
 None
 0.92A 6f6iA-5kenA:
23.7
6f6iB-5kenA:
undetectable		 6f6iA-5kenA:
98.67
6f6iB-5kenA:
15.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F6I_A_8PRA509_1
(ENVELOPE
GLYCOPROTEIN,GP,GP1
ENVELOPE
GLYCOPROTEIN)		 5ken EBOLA SURFACE
GLYCOPROTEIN, GP1
EBOLA SURFACE
GLYCOPROTEIN, GP2
(Zaire
ebolavirus) 		5 / 12 ARG A  64
LEU A 186
TYR B 517
THR B 519
MET B 548
 None
 0.99A 6f6iA-5kenA:
23.7
6f6iB-5kenA:
undetectable		 6f6iA-5kenA:
98.67
6f6iB-5kenA:
15.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F6I_A_8PRA509_1
(ENVELOPE
GLYCOPROTEIN,GP,GP1
ENVELOPE
GLYCOPROTEIN)		 5ken EBOLA SURFACE
GLYCOPROTEIN, GP1
EBOLA SURFACE
GLYCOPROTEIN, GP2
(Zaire
ebolavirus) 		6 / 12 VAL A  66
GLY A 102
LEU A 186
TYR B 517
THR B 519
LEU B 558
 None
 0.68A 6f6iA-5kenA:
23.7
6f6iB-5kenA:
undetectable		 6f6iA-5kenA:
98.67
6f6iB-5kenA:
15.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F6I_A_8PRA509_1
(ENVELOPE
GLYCOPROTEIN,GP,GP1
ENVELOPE
GLYCOPROTEIN)		 5ken EBOLA SURFACE
GLYCOPROTEIN, GP1
EBOLA SURFACE
GLYCOPROTEIN, GP2
(Zaire
ebolavirus) 		6 / 12 VAL A  66
LEU A  68
GLY A 102
LEU A 186
TYR B 517
LEU B 558
 None
 0.70A 6f6iA-5kenA:
23.7
6f6iB-5kenA:
undetectable		 6f6iA-5kenA:
98.67
6f6iB-5kenA:
15.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F6I_A_8PRA509_1
(ENVELOPE
GLYCOPROTEIN,GP,GP1
ENVELOPE
GLYCOPROTEIN)		 5ken EBOLA SURFACE
GLYCOPROTEIN, GP1
EBOLA SURFACE
GLYCOPROTEIN, GP2
(Zaire
ebolavirus) 		6 / 12 VAL A  66
LEU A  68
LEU A 186
LEU B 515
TYR B 517
LEU B 558
 None
 0.79A 6f6iA-5kenA:
23.7
6f6iB-5kenA:
undetectable		 6f6iA-5kenA:
98.67
6f6iB-5kenA:
15.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F6I_A_8PRA509_1
(ENVELOPE
GLYCOPROTEIN,GP,GP1
ENVELOPE
GLYCOPROTEIN)		 5ken EBOLA SURFACE
GLYCOPROTEIN, GP1
EBOLA SURFACE
GLYCOPROTEIN, GP2
(Zaire
ebolavirus) 		6 / 12 VAL A  66
LEU A  68
LEU A 186
LEU B 515
TYR B 517
MET B 548
 None
 0.86A 6f6iA-5kenA:
23.7
6f6iB-5kenA:
undetectable		 6f6iA-5kenA:
98.67
6f6iB-5kenA:
15.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F6I_A_8PRA509_1
(ENVELOPE
GLYCOPROTEIN,GP,GP1
ENVELOPE
GLYCOPROTEIN)		 5ken EBOLA SURFACE
GLYCOPROTEIN, GP1
EBOLA SURFACE
GLYCOPROTEIN, GP2
(Zaire
ebolavirus) 		5 / 12 VAL A  66
LEU A 186
TYR B 517
THR B 519
MET B 548
 None
 0.72A 6f6iA-5kenA:
23.7
6f6iB-5kenA:
undetectable		 6f6iA-5kenA:
98.67
6f6iB-5kenA:
15.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F6N_A_SREA508_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 5ken EBOLA SURFACE
GLYCOPROTEIN, GP1
EBOLA SURFACE
GLYCOPROTEIN, GP2
(Zaire
ebolavirus) 		5 / 10 ARG A  64
LEU A 186
TYR B 517
LEU B 554
LEU B 558
 None
 0.74A 6f6nA-5kenA:
23.3
6f6nB-5kenA:
undetectable		 6f6nA-5kenA:
98.67
6f6nB-5kenA:
15.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F6N_A_SREA508_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 5ken EBOLA SURFACE
GLYCOPROTEIN, GP1
EBOLA SURFACE
GLYCOPROTEIN, GP2
(Zaire
ebolavirus) 		5 / 10 VAL A  66
LEU A 184
LEU A 186
MET B 548
LEU B 558
 None
 1.01A 6f6nA-5kenA:
23.3
6f6nB-5kenA:
undetectable		 6f6nA-5kenA:
98.67
6f6nB-5kenA:
15.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F6N_A_SREA508_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 5ken EBOLA SURFACE
GLYCOPROTEIN, GP1
EBOLA SURFACE
GLYCOPROTEIN, GP2
(Zaire
ebolavirus) 		6 / 10 VAL A  66
LEU A 184
LEU A 186
TYR B 517
LEU B 554
LEU B 558
 None
 0.78A 6f6nA-5kenA:
23.3
6f6nB-5kenA:
undetectable		 6f6nA-5kenA:
98.67
6f6nB-5kenA:
15.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F6S_B_CXQB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 5ken EBOLA SURFACE
GLYCOPROTEIN, GP1
EBOLA SURFACE
GLYCOPROTEIN, GP2
(Zaire
ebolavirus) 		4 / 6 VAL A  66
LEU A 184
LEU A 186
MET B 548
 None
 1.02A 6f6sA-5kenA:
23.6
6f6sB-5kenA:
undetectable		 6f6sA-5kenA:
98.67
6f6sB-5kenA:
15.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
6F6S_B_CXQB705_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 5ken EBOLA SURFACE
GLYCOPROTEIN, GP1
EBOLA SURFACE
GLYCOPROTEIN, GP2
(Zaire
ebolavirus) 		5 / 6 VAL A  66
LEU A 184
LEU A 186
TYR B 517
LEU B 554
 None
 0.86A 6f6sA-5kenA:
23.6
6f6sB-5kenA:
undetectable		 6f6sA-5kenA:
98.67
6f6sB-5kenA:
15.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGC_A_ACTA811_0
(GEPHYRIN)		 5ken EBOLA SURFACE
GLYCOPROTEIN, GP1
(Zaire
ebolavirus) 		3 / 3 LEU A 184
LEU A 186
ARG A  64
 None
 0.68A 6fgcA-5kenA:
undetectable		 6fgcA-5kenA:
21.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA810_0
(GEPHYRIN)		 5ken EBOLA SURFACE
GLYCOPROTEIN, GP1
(Zaire
ebolavirus) 		3 / 3 LEU A 184
LEU A 186
ARG A  64
 None
 0.67A 6fgdA-5kenA:
undetectable		 6fgdA-5kenA:
21.72