SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5keu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4F_B_ADNB602_2
(S-ADENOSYLHOMOCYSTEI
NE HYDROLASE)		 5keu TAURINE DIOXYGENASE
(Paraburkholderia
xenovorans) 		4 / 5 THR A 145
THR A 245
GLU A 243
HIS A 238
 None
 1.43A 1d4fB-5keuA:
undetectable		 1d4fB-5keuA:
21.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OD9_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 5keu TAURINE DIOXYGENASE
(Paraburkholderia
xenovorans) 		3 / 3 PHE A  71
PHE A 257
PHE A  54
 None
 0.83A 2od9A-5keuA:
undetectable		 2od9A-5keuA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QQG_A_NCAA3721_0
(NAD-DEPENDENT
DEACETYLASE HST2)		 5keu TAURINE DIOXYGENASE
(Paraburkholderia
xenovorans) 		3 / 3 PHE A  71
PHE A 257
PHE A  54
 None
 0.83A 2qqgA-5keuA:
undetectable		 2qqgA-5keuA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZU_A_9CRA7223_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5keu TAURINE DIOXYGENASE
(Paraburkholderia
xenovorans) 		5 / 12 ILE A 129
ALA A 127
ILE A  42
PHE A  71
LEU A 285
 None
 0.82A 3dzuA-5keuA:
undetectable		 3dzuA-5keuA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P73_A_ACTA275_0
(MHC RFP-Y CLASS I
ALPHA CHAIN)		 5keu TAURINE DIOXYGENASE
(Paraburkholderia
xenovorans) 		3 / 3 ILE A 301
VAL A 168
ARG A 170
 None
 0.74A 3p73A-5keuA:
undetectable		 3p73A-5keuA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1161_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 5keu TAURINE DIOXYGENASE
(Paraburkholderia
xenovorans) 		5 / 12 PHE A  53
PHE A  54
LEU A  34
GLN A  41
ALA A  45
 None
 1.43A 4a84A-5keuA:
undetectable		 4a84A-5keuA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_2
(NEURAMINIDASE)		 5keu TAURINE DIOXYGENASE
(Paraburkholderia
xenovorans) 		3 / 3 ARG A  48
ARG A  50
TRP A  49
 None
None
FMT  A 407 ( 4.4A)
 1.07A 4cpzC-5keuA:
undetectable		 4cpzC-5keuA:
20.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I41_A_MIXA500_2
(SERINE/THREONINE-PRO
TEIN KINASE PIM-1)		 5keu TAURINE DIOXYGENASE
(Paraburkholderia
xenovorans) 		4 / 4 LEU A  59
LEU A 130
GLN A  70
GLU A  89
 None
 1.11A 4i41A-5keuA:
undetectable		 4i41A-5keuA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K6I_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5keu TAURINE DIOXYGENASE
(Paraburkholderia
xenovorans) 		5 / 12 ILE A 129
ALA A 127
ILE A  42
PHE A  71
LEU A 285
 None
 0.90A 4k6iA-5keuA:
undetectable		 4k6iA-5keuA:
23.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M6T_A_SAMA201_0
(RNA POLYMERASE
II-ASSOCIATED FACTOR
1 HOMOLOG, LINKER,
RNA
POLYMERASE-ASSOCIATE
D PROTEIN LEO1)		 5keu TAURINE DIOXYGENASE
(Paraburkholderia
xenovorans) 		4 / 4 ILE A 129
VAL A  52
VAL A 255
ARG A 131
 None
 1.36A 4m6tA-5keuA:
undetectable		 4m6tA-5keuA:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA310_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5keu TAURINE DIOXYGENASE
(Paraburkholderia
xenovorans) 		3 / 3 GLU A 207
HIS A 202
ARG A 200
 None
 0.89A 5uunA-5keuA:
undetectable		 5uunA-5keuA:
21.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_B_ADNB503_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 5keu TAURINE DIOXYGENASE
(Paraburkholderia
xenovorans) 		4 / 5 LEU A  30
VAL A  28
GLU A  38
LEU A  34
 None
 0.98A 5xooB-5keuA:
undetectable		 5xooB-5keuA:
12.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6D8F_A_ACTA803_0
(UNCHARACTERIZED
PROTEIN)		 5keu TAURINE DIOXYGENASE
(Paraburkholderia
xenovorans) 		3 / 3 GLU A 152
LEU A 149
ARG A  50
 None
 0.82A 6d8fA-5keuA:
undetectable		 6d8fA-5keuA:
18.42